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Stroke clinical trials

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NCT ID: NCT04995705 Terminated - Stroke Clinical Trials

Evaluation of an Adapted ACT Group for Stroke & Brain Injury Survivors

Start date: April 8, 2019
Phase: N/A
Study type: Interventional

Stroke and Acquired Brain Injury (ABI) represent a major cause of long-term disability among survivors. Many psychological difficulties can also occur including: depression, anxiety, fatigue, and post-traumatic stress disorder. This has a marked impact on health service usage. Despite certain interventions being offered to support stroke survivors and individuals with brain injury, there is still an outstanding need to increase and improve psychological resources for this population. This research proposes to evaluate the effectiveness of a group therapy intervention, using a model called Acceptance and Commitment Therapy (ACT), for stroke survivors and adults with ABI. This ACT group aims to promote positive adjustment and improve wellbeing, whilst also aiming to reduce levels of distress. The research will comprise of two parts (one quantitative and the other qualitative).

NCT ID: NCT04733339 Terminated - Stroke, Ischemic Clinical Trials

Investigating Adherence to Cereneo Tele-service Support After Clinical Disharge in Stroke Patients

Start date: July 11, 2019
Study type: Observational [Patient Registry]

This observational, prospective cohort, pilot study aims at investigating usability, operational, and economical factors around 'traditional' and 'technology-supported' approaches to promote a healthy life-style in stroke survivors, after discharge from an in-patient clinic. The investigators primary objective is to evaluate the adherence to prescribed behavioral changes in dieting and exercising up to one year after clinical discharge. This pilot study will follow and document the observations of two groups of patients, one offered a 'traditional' and another one a 'technology-supported' approach by the healthcare provider. The investigators secondary objective is to gain insights on how to efficiently (and securely) facilitate remote counselling once patients get discharged from the clinic.

NCT ID: NCT04698369 Terminated - Stroke Clinical Trials

Evaluation of Vibration-based Wearable Upper Limb Rehabilitation Device

Start date: August 30, 2021
Phase: N/A
Study type: Interventional

The investigators will perform a pilot 4-week at home study with 48 individuals with stroke and 10 therapists working with stroke patients to examine the feasibility and effect of a wearable focal muscle vibration device on upper limb strength and function.

NCT ID: NCT04576013 Terminated - Stroke Clinical Trials

Peripheral Nerve Stimulation to Improve Upper Extremity Function After Severe Stroke

Start date: February 23, 2016
Phase: N/A
Study type: Interventional

Subjects will receive non-invasive stimulation of nerves on their arm and intensive motor training of their arm. The timing of the stimulation in relation to the training will vary by group.

NCT ID: NCT04574973 Terminated - Stroke Clinical Trials

Optimizing Transcranial Direct Current Stimulation for Motor Recovery From Severe Post-stroke Hemiparesis

Start date: November 28, 2018
Phase: N/A
Study type: Interventional

Individuals who experienced a stroke over one year ago will be randomly assigned to receive 1 of 4 different conditions of brain stimulation. All individuals will receive therapy of the hand and arm following the stimulation. This study will try to determine which brain stimulation condition leads to the greatest improvement in hand and arm function.

NCT ID: NCT04502927 Terminated - Stroke Clinical Trials

Measurements of Displacement Amplitude and Angular Velocities During Passive Extension of the Wrist and Hand Complex in Stroke Patients

Start date: March 10, 2020
Phase: N/A
Study type: Interventional

The main objective of this monocentric prospective study is to evaluate the amplitudes and angular velocities of extension of the hand and wrist joints during passive mobilization by a physiotherapist in healthy subjects and stroke patients with spastic hands. Secondary objectives: - To compare amplitude and angular velocity values between the group of stroke patients and the group of healthy volunteers, - To compare amplitude and angular velocity values according to the two types of mobilization (i,e, thumb or fifth finger), - To assess pain due to mobilization in stroke patients.

NCT ID: NCT04282564 Terminated - Clinical trials for Cerebrovascular Accident

Improvement of Executive Functions With the CO-OP Method in the Adult Subject After Stroke

Start date: February 24, 2020
Phase: N/A
Study type: Interventional

The research focuses on top-down intervention approaches and more specifically on the Cognitive Orientation to daily Occupational Performance (CO-OP) method in the rehabilitation of executive function disorders in adult post-stroke subjects in chronic phase. The main objective of this study is therefore to improve performance in significant activities of daily living for people with chronic post-stroke dysexecutive disorders.

NCT ID: NCT04266158 Terminated - Stroke Clinical Trials

FAME: Functional Assessment of a Myoelectric Orthosis Hand Orthoses

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

The primary study objective is to compare post-stroke upper extremity (UE) movement while wearing a brace called the MyoPro 2 Motion G versus UE movement while wearing a resting splint and no device in stroke survivors with moderate UE dysfunction. During the study, subjects will undergo general training in the operation of the EMG-controlled orthosis and the comparison orthosis, and then guided through a series of standard clinical outcome measures. These outcome measures will allow the researchers to directly compare the relative benefit of the MyoPro 2 Motion G with a resting hand splint and no device in reducing UE impairment and increasing UE dexterity and functional task performance.

NCT ID: NCT04199793 Terminated - Stroke Clinical Trials

Lavare Cycle in Patients Receiving HeartWare Left Ventricular Assist Device

Start date: August 10, 2020
Phase: N/A
Study type: Interventional

Left ventricular assist device (LVAD) patients remain at risk for pump thrombus and thromboembolic events through multiple mechanisms. The HeartWare® Ventricular Assist System (HVAD®, HeartWare Inc., Framingham, MA, USA) includes a novel speed modulation feature called Lavare™ cycle. The Lavare™ Cycle is aimed to promote washing of left ventricle to decrease blood stasis and subsequent risk of thrombus formation, ingestion and/or expulsion. No prior study has prospectively evaluated the impact of Lavare™ cycle on patient outcomes in a randomized fashion. We intend to assess effects of Lavare™ Cycle among patients receiving HVAD LVAD in this randomized controlled pilot project.

NCT ID: NCT04180826 Terminated - Ischemic Stroke Clinical Trials

STAND: iSchemic sTroke evAluated at Bed Side With ultrasouND

Start date: January 15, 2019
Study type: Observational

Ischemic strokes account for more than 80% of strokes. Ischemic strokes are caused by the occlusion of an intracranial artery by a thrombus, responsible for tissue ischemia related to a decrease in local cerebral blood flow (CBS). Thus, the management of patients with Ischemic strokes is based on the preservation of an area that maintains sufficient intracranial hemodynamics (IH) and achieves the fastest possible recanalization. The impact of the patient's position (supine or seated position) on the IH in the event of narrowing or occlusion of an artery is poorly assessed but may be of particular importance. In practice, variations in blood flow according to the positioning of the patient's body can be measured using a transcranial Doppler. It is a simple, non-invasive and painless examination that provides the patient's bed with data on the intracerebral hemodynamic profile of patients. This study was implemented because there are no studies known to us that evaluate the effect of verticalization on intracerebral hemodynamics based on the presence of upstream arterial stenosis or occlusion and other multimodal evaluation data in transcranial Doppler.