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NCT ID: NCT01389024 Recruiting - Clinical trial for Stroke

Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease

Start date: October 2011
Phase: Phase 2
Study type: Interventional

This is a pilot study of hydroxyurea versus placebo to reduce central nervous system complications (abnormally fast blood flow to the brain, silent cerebral infarct or stroke) in young children with sickle cell disease. The investigators plan to identify children 12 to 48 months old without central nervous system complications and randomly assign 20 to treatment with hydroxyurea and 20 to treatment with placebo for 36 months. Neither the study doctors nor the participants will know which treatment they are receiving.

NCT ID: NCT01384721 Recruiting - Clinical trial for Coronary Artery Disease

Computed Tomography Coronary Angiography (CTCA) Prognostic Registry for Coronary Artery Disease

Start date: September 2010
Study type: Observational

The study aims at pooling a large population of patients with suspected coronary artery disease (CAD) who underwent Computed Tomography Coronary Angiography (CTCA) and who were adequately stratified in the first place. Then the investigators will be able to assess the incremental value of CTCA in the stratification of prevalence of disease (non obstructive/obstructive) and prognosis of patients with suspected CAD). The added information to current evidence is how reliable and to what extent CTCA can define the actual burden of disease and cardiovascular risk.

NCT ID: NCT01376661 Recruiting - Clinical trial for Prostate Cancer

Outcome Assessment of an Active Surveillance Program for Low Risk Prostate Cancer: An Observational Study

Start date: May 2009
Phase: N/A
Study type: Observational

The purpose of this research study is to monitor the feasibility and outcome of the Active Surveillance Program for men with low risk prostate cancer.