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NCT ID: NCT01374412 Recruiting - Clinical trial for Multiple Myeloma

Investigation of Bone Defects and Microcirculation With Computed Tomography and Magnetic Resonance Imaging

Start date: July 2010
Phase: N/A
Study type: Observational

Subject of the proposed study is the non-invasive in vivo imaging of bone, bone marrow and localized microcirculation in test animals with osteoporosis, fractures and after placement of bone substitute material with volume computed tomography (VCT) (animals only) and functional magnetic resonance imaging (MRI). Furthermore patients with multiple myeloma (MM) will be examined before and after placement of a commercially available bone substitute material. Osseous structures before intervention and structural changes of the bone especially at the junction of substitute material and residual bone will be documented. At this, the proposed techniques allow imaging of the dynamic healing processes in the living organism.

As next step patients with asymptomatic MM will be investigated with functional Imaging longitudinally to predict the occurence of osteolyses at time of Progression.

Hypothesis: Affection of microcirculation at the junction of bone and bone substitute material can be displayed by VCT and functional MRI

NCT ID: NCT01368588 Recruiting - Clinical trial for Prostate Cancer

Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

Start date: July 2011
Phase: Phase 3
Study type: Interventional

RATIONALE: Androgens can cause the growth of prostate cancer cells. Androgen deprivation therapy may stop the adrenal glands from making androgens. Radiation therapy uses high-energy x-rays to kill tumor cells.

PURPOSE: This randomized phase III trial studies androgen-deprivation therapy and radiation therapy in treating patients with prostate cancer.

NCT ID: NCT01366404 Recruiting - Clinical trial for Coronary Artery Disease

Study of the Natural History of FFR Guided Percutaneous Coronary Intervention

IRIS FFR
Start date: June 2011
Phase:
Study type: Observational

About 15,000 patients with FFR (Fractional Flow Reserve) will be enrolled and evaluated for the natural history of coronary lesions at 2 years clinical and imaging follow-up.