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NCT ID: NCT01422421 Recruiting - Clinical trial for Hypertension

Intensive Blood Pressure and LDL Lowering in Diabetic Patients With Coronary Artery Disease

Start date: August 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether intensive blood pressure and low density lipoprotein (LDL) cholesterol lowering could improve survival and cardiovascular outcome in Japanese diabetic patients with coronary artery disease and history of acute coronary syndrome.

NCT ID: NCT01421810 Recruiting - Clinical trial for Obesity

Ovarian Contribution to Androgen Production in Adolescent Girls

CBS001
Start date: December 2010
Phase: N/A
Study type: Interventional

Women with polycystic ovary syndrome (PCOS) can have unwanted facial or male-patterned body hair, irregular menstrual periods, or no menstrual periods excess body weight, and infertility. It also results in elevated androgen levels such as testosterone. In women with PCOS, the majority of excess androgens are produced by the ovaries. However, it is unknown whether the ovaries are fully active during early puberty. The purpose of this study is to determine how the ovaries contribute to the production of male hormones in the body during different stages of puberty, so that it can be better understood why some females have excess androgens.

NCT ID: NCT01421797 Recruiting - Clinical trial for Obesity

Evaluation of Adrenal Androgens in Normal and Obese Girls After Suppression and Stimulation

Start date: October 10, 2006
Phase: N/A
Study type: Interventional

Women with polycystic ovary syndrome (PCOS) often have irregular menstrual periods, too much facial and body hair, and weight gain. Women with PCOS also have a hard time becoming pregnant. Girls with high levels of the male hormone testosterone often develop PCOS as adults. Some girls with high levels of male hormone will develop normal hormone levels as they grow up, but most girls continue to have high levels of male hormone as adults. The purpose of this study is to understand where the male and female hormones come from in girls as they get older. The investigators think the adrenal gland, makes most of the hormones in young girls and that the ovary and the adrenal gland make these hormones in older girls. The investigators would like to find out whether an overactive adrenal gland makes these hormones higher in girls who are overweight, compared to those who are not overweight.