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Stroke clinical trials

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NCT ID: NCT06152328 Enrolling by invitation - Stroke Clinical Trials

Virtual Reality Based Mirror Therapy

Start date: November 15, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to examine the effectiveness of 3D virtual reality assisted mirror therapy based rehabilitation applications compared to classical methods used in stroke rehabilitation.

NCT ID: NCT06126523 Enrolling by invitation - Stroke Clinical Trials

Effect of ESWT Applied After Botulinum Toxin Injection on Ankle Spasticity in Stroke Patients.

Start date: November 8, 2023
Phase: N/A
Study type: Interventional

Stroke is the second most common cause of death and the third most important cause of disability worldwide, with an annual death rate of 5.5 million. Spasticity is a common condition in stroke patients and has a negative impact on daily living activities. BTX-A has been successfully used in the treatment of spasticity in patients with stroke. ESWT is a physical therapy method applying high intensity pressure waves. ESWT has been increasingly used in the management of spasticity as a safe and effective method, but the literature about ESWT in spasticity is heterogeneous and the treatment protocols are not very clear about the number of applications. The aim of this study is to determine the effects of rESWT treatment on ankle plantar flexors spasticity applied after BTX-A injection.

NCT ID: NCT06108102 Enrolling by invitation - Stroke Clinical Trials

International Post-Stroke Epilepsy Research Repository

IPSERR
Start date: December 2023
Phase:
Study type: Observational [Patient Registry]

The International Post-Stroke Epilepsy Research Repository (IPSERR): The study aims to collate and categorize data reported by post-stroke epilepsy (PSE) researchers and lodge it within the IPSERR. Using the IPSERR database, we will conduct two individual patient data (IPD) analyses: (1) determine epilepsy, functional, and cognitive outcomes in stroke patients who develop post-stroke seizure and (2) build and validate post-stroke epilepsy prediction model and compare performance against existing models.

NCT ID: NCT06074081 Enrolling by invitation - Acute Stroke Clinical Trials

Comparison of 4-weeks of Motor Relearning Program and Mirror Therapy in Improving Upper Limb Motor Function in Stroke Patients.

Start date: September 4, 2023
Phase: N/A
Study type: Interventional

Cerebrovascular accident(CVA) or stroke is one of common condition affecting people in developed and underdeveloped countries. MRP is a therapy to regain particular motor function and neglecting accessory movements by engaging cognitive behavior. Mirror therapy enhance functional activities in patient with hemiplegic stroke. For betterment of result high quality methodological studies and larger sample size is required.

NCT ID: NCT06003790 Enrolling by invitation - Chronic Stroke Clinical Trials

Facilitators and Barriers to the Clinical Implementation of MR-001

RhaPSody
Start date: August 29, 2023
Phase: N/A
Study type: Interventional

This is a single arm, multi-site, prospective hybrid implementation and feasibility trial. The primary purpose of this trial is to gather data on the facilitators and barriers to clinical implementation of MR-001 for patients with chronic stroke who experience walking impairments. Secondarily, the trial will evaluate the feasibility of MR-001 clinically impacting walking capacity, quality of life, mood, and cognition. The goal of this single arm, multi-site, prospective hybrid implementation and feasibility trial is to gather data on the facilitators and barriers to clinical implementation of MR-001 for patient with chronic stroke who experience walking impairments. The main questions it aims to answer are: 1. Enhance understanding of the potential clinical and operational needs and opportunities that may be associated with implementation of MR-001 in various treatment settings. 2. Assess the impact of MR-001 on walking capacity. 3. Assess the impact of MR-001 on quality of life and mood. 4. Assess the impact of MR-001 on cognition. All participants will be prescribed MR-001 and will be asked to walk with it for 30 minutes, 3 times weekly, for 8 weeks.

NCT ID: NCT05989945 Enrolling by invitation - Stroke Clinical Trials

HIDRAdenitis Suppurativa and HEART Disease

Start date: August 1, 2023
Phase:
Study type: Observational

In a prospective observational cohort study (n = 250) the investigators aim to assess the correlation between cardiac biomarkers, advanced echocardiography and HS severity and determine whether these are prognostic markers of heart disease in patients suffering from hidradenitis suppurativa (HS).

NCT ID: NCT05970406 Enrolling by invitation - Clinical trials for Dysphagia Following Cerebrovascular Accident

High Intensity Dysphagia Rehab for Acute Ischemic Stroke Patients

Start date: November 30, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine a standardized protocol for swallowing therapy and this protocol's effects on recovery after a stroke

NCT ID: NCT05947773 Enrolling by invitation - Stroke Clinical Trials

Effect of Robotic Treatments on Motor Functions in Subacute Stroke Patients

Start date: July 9, 2023
Phase: N/A
Study type: Interventional

We are conducting a three-group comparative study on stroke patients. The treatment is started in a subacute state and completed in the hospital. The essence of robot-assisted treatments is faster recovery and better learning to walk. The group will do a special walking exercise with a robot. The walking group does the same training, only without robotic assistance. The control group will receive physiotherapy treatments financed by the state. Control examination after 3 weeks.

NCT ID: NCT05920993 Enrolling by invitation - Clinical trials for Cerebrovascular Accident

The Performances and Differences in Tongue Function Between Healthy Adults and Dysphagia in Patients With Stroke in Taiwan

Start date: January 17, 2023
Phase:
Study type: Observational

Cerebrovascular accident makes adults lose the ability to be independent in daily life, and a higher proportion of them will suffer from dysphagia. Previous studies pointed out that the tongue muscle strength of stroke patients is significantly lower than that of healthy adults. Furthermore, the tongue strength of stroke patients with dysphagia is significantly lower than those without dysphagia. Many studies investigated the performance of tongue function in healthy adults or groups with dysphagia caused by different diseases. However, the current research on the performance of tongue function in healthy adults and stroke patients in Taiwan is relatively lacking. Therefore, our purpose of this study is to investigate the performance and differences of tongue function between healthy adults and strokes patients in Taiwan. This study is expected to recruit 32 healthy adults and stroke patients in each group. The two groups will be matched with each other by gender and age (±2 years). In the study, Mann assessment of swallowing ability (MASA) will be used as an assessment tool to distinguish whether the subjects are accompany with dysphagia and the severity of dysphagia. And using Iowa Oral Performance Instrument (IOPI) to measure the value of tongue pressure. Then, analyze whether there are significant differences and the correlations. To provide clinicians with empirical data for early detection and intervention of swallowing.

NCT ID: NCT05905900 Enrolling by invitation - Stroke Clinical Trials

Emergent Prep for IV Dye in Acute Stroke Patients With Allergy

Start date: January 1, 2015
Phase:
Study type: Observational

Our institution implemented a protocol to administer an emergent IV dye preparation for stroke alert patients requiring advanced neuroimaging. The emergent IV dye preparation consists of diphenhydramine 50 mg IV once, famotidine 20 mg IV once, and dexamethasone 10 mg IV once, followed immediately by Computed Tomography (CT) Angiography and/or CT Perfusion.