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Stroke clinical trials

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NCT ID: NCT04743076 Suspended - Clinical trials for Vertebrobasilar Stroke

A Randomized Trial Of Endovascular Treatment For Acute Posterior Large Vessel Occlusion

BASILAR-2
Start date: March 16, 2021
Phase: N/A
Study type: Interventional

The aim of this trial is to investigate whether endovascular treatment can improve the 90-day functional outcome of acute large vessel occlusion in the posterior circulation.

NCT ID: NCT04436770 Suspended - Stroke Sequelae Clinical Trials

Medical Recovery and Social Reintegration for Post-stroke Patients Using Virtual Reality

Start date: July 18, 2019
Phase: N/A
Study type: Interventional

Application of Virtual Reality therapy and occupational therapy versus and standard physiotherapy and occupational therapy to patients with post-stroke sequelae, using specifical assessment tools, standard physiotherapy and occupational therapy programs.

NCT ID: NCT04139980 Suspended - Stroke Clinical Trials

Virtual Reality Device for Rehabilitation of Stroke Patients

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

This study will evaluate the potential efficacy and safety of using virtual reality gaming in conjunction to standard therapy regimen care as an approach to promote upper-limb motor recovery, cognitive function and quality of life after stroke. The investigators believe that allowing users to interact with a computer-simulated reality environment will result in a pleasant experience, which will likely result in motivation and therapy engagement.

NCT ID: NCT04105257 Suspended - Stroke, Acute Clinical Trials

Evaluation of Diagnostic Performance of Cerebral Perfusion Scans in Pseudo-Stroke

CTP
Start date: October 20, 2019
Phase: N/A
Study type: Interventional

When a patient is received with the context of acute stroke, they undergo a fast neurological evaluation and obtain a basic appraisal composed of a non-contrast endovascular cerebral scan and an angiography scan of intracranial blood vessels and the neck. Once the structural lesion (hemorrhage, tumor, etc.) is absent, signs of early infracts and confirmed acute intracranial arterial occlusion, the possibility of a pseudo-stroke dwells in the differential diagnostic. Certain characteristics of history and clinical evaluation create sufficient doubt to evoke the possibility of a pseudo-stroke. In fact, this population is mostly female and the cardiovascular risk factors are less prevalent in this group than for the group of stroke victims. It is on average the youngest and presents a less severe deficit. For the rest, medical antecedents often help to evoke a diagnosis of pseudo-stroke.

NCT ID: NCT04062539 Suspended - Stroke Clinical Trials

Total Cerebral Protection With Embolic Protection Devices Thoracic Aortic Stenting

Start date: October 4, 2018
Phase:
Study type: Observational

Stroke and silent cerebral infarction are a real risk with thoracic enodvascular aortic repair (TEVAR). The investigator propose to prospectively observational study with enrolment of all patients undergoing TEVAR for thoracic and thoracoabdominal conditions including aneurysmal degeneration, Type B dissection and acute aortic syndromes over a 24 month period, equating to a minimum of 20-30 patients per year. Patients undergoing juxtra-renal and infra-renal aortic stenting will form a control group.

NCT ID: NCT04048668 Suspended - Stroke, Acute Clinical Trials

tDCS to Treat Subacute Aphasia

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

This study proposes to use transcranial direct current stimulation (tDCS), a technique by which a very small electrical current (2 mA) is applied to the scalp, along side speech therapy in patients with subacute stroke and aphasia in order to enhance language recovery. Aphasic patients in an inpatient neurorehabilitation facility who have experienced a stroke between one week and three months prior to enrollment will be invited to participate. Participants will receive either real or sham tDCS to the left hemisphere of the brain for a minimum of 5 consecutive sessions to up-to a max of 10 sessions depending on the length of their rehab stay . Stimulation will be paired with with the patient's normal speech therapy schedule. Participant's language skills will be assessed at baseline and immediately after the last session of therapy in order to determine whether tDCS is associated with either transient or persistent improvement in language.

NCT ID: NCT04038424 Suspended - Clinical trials for Ischemic Stroke and Hemorrhagic Stroke

The Effect of Art Therapy on Patients With Stroke

Start date: September 20, 2019
Phase: N/A
Study type: Interventional

Stroke can affect the physical, emotional and social aspects of the patient and their family members. It is the main cause of complex disability, with a high number of people living with its effects. Stroke can result in impairments in motor function, language, cognition, sensory processing, cognition, and emotional disturbances, which can affect the performance of functional activities and mental health status. Getting patients involved in art therapy (AT) class has shown to alleviate stress and promote a sense of wellbeing, which can aid their recovery and rehabilitation. The benefits of art therapy for people living with different health conditions worldwide have been reported, however, its effect on Egyptian patients with stroke has been neglected.

NCT ID: NCT04007315 Suspended - Stroke Clinical Trials

SaeboGlove Therapy for Severe Upper Limb Disability and Severe Hand Impairment After Stroke

SUSHI
Start date: November 21, 2019
Phase: N/A
Study type: Interventional

The study will aim to determine whether 6-weeks of using a SaeboGlove independently (with or without help from a carer) improves upper limb function (measured using the Action Research Arm Test score) in comparison to usual care alone in people with reduced active finger extension, severe upper limb disability and severe hand impairment after recent stroke.

NCT ID: NCT03969095 Suspended - Stroke Clinical Trials

Tongue Pressure Resistance Training for Swallowing Impairment Post-Stroke

TPRT-SIPS
Start date: April 1, 2019
Phase: N/A
Study type: Interventional

For patients who have suffered a stroke, tongue strength may be decreased compared to healthy individuals. Research on strengthening the tongue in the stroke population has shown positive effects of a tongue resistance training protocol. Research also suggests that swallow safety, or protection of the airway, may be improved as a result of such interventions, however the mechanism of improvement remains poorly understood. This study aims to determine what aspects of the swallowing mechanism (response time, movement, etc. of different structures) are directly impacted in order to provide guidance to clinicians using such treatments.

NCT ID: NCT03869138 Suspended - Stroke Clinical Trials

Alternative Therapies for Improving Physical Function in Individuals With Stroke

Start date: September 9, 2019
Phase: N/A
Study type: Interventional

Neurological impairment is a devastating disease for patients and their families and a leading cause of adult disability. Traditional rehabilitative therapies can help regain motor function and ameliorate disability. However, health care reimbursed rehabilitation is usually provided for up to 6 months post stroke (3 months in form of inpatient therapy and 3 months in outpatient therapy). There are increasing community and other facilities offering rehabilitation in form of conventional, recreational and alternative (Yoga, Tai-chi) therapy. However, implementation of these conventional therapy techniques in individuals with neurological disorder impairments is tedious, resource-intensive, and costly, often requiring transportation of patients to specialized facilities. Based on recent evidence suggesting significant benefits of repetitive, task-orientated training, investigators propose to evaluate the feasibility of an alternative dance and gaming based virtual dance and gaming based therapy to improve overall physical function of community-dwelling individuals with neurological impairments, compared to conventional therapeutic rehabilitation. This pilot study aims to systematically obtain pilot data on compliance and efficacy as well as performing power analysis and sample size calculation for developing it into a randomized controlled trial for extramural funding purposes. The objective of the study is to determine the safety, feasibility, compliance and efficacy of an alternative dance and gaming-based virtual gaming therapy to improve overall physical function of community-dwelling individuals with neurologically impairment and compare it to that of conventional rehabilitation and also to determine the gains in community participation and integration with longer-term compliance to the dance and gaming -based intervention.