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Stroke clinical trials

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NCT ID: NCT05671874 Suspended - Clinical trials for Traumatic Brain Injury

Feasibility of a Digital Goals-of-Care Decision Aid for Clinicians and Families of Patients With SABI

Start date: March 28, 2023
Phase: N/A
Study type: Interventional

The goal is to pilot test a highly accessible, web-based, pragmatic, scalable intervention to overcome ongoing problems with high stakes decision-making by surrogate decision-makers of patients in ICUs with severe acute brain injury (SABI), including those with moderate-severe traumatic brain injury, large hemispheric acute ischemic stroke and intracerebral hemorrhage.

NCT ID: NCT05262699 Suspended - Stroke Clinical Trials

Crossmodal Learning in Therapeutic Processes (Task 2-1)

Start date: April 14, 2021
Phase: N/A
Study type: Interventional

Interventional study of the effects of vibro-tactile feedback on behavioral deficits and learning during motor training in patients with stroke.

NCT ID: NCT05006248 Suspended - Stroke Clinical Trials

Robotic Interventions for Spasticity Treatment

Start date: March 27, 2022
Phase: N/A
Study type: Interventional

The researchers have developed games controlled by electromyographic (EMG) and inertial measurement unit (IMU) activity recorded by a sensor. These will provide biofeedback to participants post-stroke about the activity of their paretic muscles. The researchers anticipate that providing visual biofeedback will allow subjects to observe the level of co-activation in an agonist-antagonist muscle pair, and therefore initiate interventions to reduce their level of co-activation. Similarly, the researchers will provide additional haptic feedback using an assistive robot at the ankle joint (i.e., M1) and compare the results with the pure visual feedback condition. At the end, the main objective is to compare 1) conventional robotic continuous passive movement (CPM) training to 2) training with visual biofeedback and 3) training with both visual and haptic biofeedback.

NCT ID: NCT04891913 Suspended - Clinical trials for Acute Ischemic Stroke

SY007 in Patients With Acute Ischemic Stroke

Start date: July 1, 2023
Phase: Phase 1
Study type: Interventional

This Phase 1b multiple center, randomized, double-blind, placebo-controlled study is a dose escalation trial evaluating the safety, tolerability, PK characteristics and efficacy of SY-007 after injection in acute ischemicstroke patients. The immunogenicity of SY-007 will be evaluated and this study will provide the recommended dosage for subsequent clinical trials.

NCT ID: NCT04743076 Suspended - Clinical trials for Vertebrobasilar Stroke

A Randomized Trial Of Endovascular Treatment For Acute Posterior Large Vessel Occlusion

Start date: March 16, 2021
Phase: N/A
Study type: Interventional

The aim of this trial is to investigate whether endovascular treatment can improve the 90-day functional outcome of acute large vessel occlusion in the posterior circulation.

NCT ID: NCT04436770 Suspended - Stroke Sequelae Clinical Trials

Medical Recovery and Social Reintegration for Post-stroke Patients Using Virtual Reality

Start date: July 18, 2019
Phase: N/A
Study type: Interventional

Application of Virtual Reality therapy and occupational therapy versus and standard physiotherapy and occupational therapy to patients with post-stroke sequelae, using specifical assessment tools, standard physiotherapy and occupational therapy programs.

NCT ID: NCT04339699 Suspended - Stroke, Ischemic Clinical Trials

NobleStitch EL STITCH Trial is a PFO Comparative Trial

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

STITCH - Prospective Multi-Center Comparative Parallel Concurrent Study of the NobleStitchâ„¢ EL versus FDA-approved Amplatzer Occluder device for closure of Patent Foramen Ovale to prevent recurrent Ischemic stroke.

NCT ID: NCT04290988 Suspended - Stroke Clinical Trials

Circuitry Assessment and Reinforcement Training Effects on Recovery

Start date: September 23, 2020
Phase: N/A
Study type: Interventional

This study investigates if electroencephalography (EEG) neurofeedback training is more beneficial than sham feedback training for the improvement of communication, anxiety, and sleep quality in individuals with aphasia. Half of the participants will receive active EEG neurofeedback sessions first, followed by sham feedback sessions in a crossover design. The other half of participants will undergo sham feedback sessions first, followed by active neurofeedback.

NCT ID: NCT04288960 Suspended - Stroke Clinical Trials

Validity of a Belt Mounted Accelerometer to Assess Walking Measures in Patients With Chronic Stroke

Start date: September 1, 2022
Study type: Observational

The aim of this study is to validate the G-walk for several gait parameters, tested against a gold standard three dimensional camera system. This research will inform researchers and practitioners as to whether the G-Walk is a suitable and valid tool to easily assess walking ability in people with chronic stroke.

NCT ID: NCT04062539 Suspended - Stroke Clinical Trials

Total Cerebral Protection With Embolic Protection Devices Thoracic Aortic Stenting

Start date: October 4, 2018
Study type: Observational

Stroke and silent cerebral infarction are a real risk with thoracic enodvascular aortic repair (TEVAR). The investigator propose to prospectively observational study with enrolment of all patients undergoing TEVAR for thoracic and thoracoabdominal conditions including aneurysmal degeneration, Type B dissection and acute aortic syndromes over a 24 month period, equating to a minimum of 20-30 patients per year. Patients undergoing juxtra-renal and infra-renal aortic stenting will form a control group.