Although there are many definitions of clinical trials, they are generally considered to be biomedical or health-related research studies in human beings that follow a pre-defined protocol. We have both interventional & observational types of clinical trials found on this site.
Myofascial pain syndrome is a common cause of chronic pain characterized by myofascial pain and trigger points. Recommendations regarding management of pain after breast cancer don't mention myofascial syndrome despite a study suggests possible myofascial syndrome with roughly 75% of patients in pain. 144 patients having a local breast cancer requiring surgery will be randomized in this study, ratio 1:1 standard and experimental groups. Every patients (standard and experimental groups) will attend 4 specific consultations during which standard recommendations will be given, pain, quality of life, shoulder range of motion, global upper limbs force will be assessed. In addition, patient randomized in experimental group will attend self massages and self stretching workshops, one before surgery and one after surgery. Patients will be encouraged to performed daily self massages and self stretching. The aim of the study is to assess impact of self massages and self stretching workshops on sequelae pain further surgery for breast cancer.
This is a phase II open-label, multicentre, randomized trial. The study assesses the treatment of postmenopausal patients with hormone receptor positive/HER2 positive early breast cancer with neoadjuvant palbociclib in combination with hormonal therapy and HER2 blockade, versus the treatment with paclitaxel in combination with HER2 blockade.
Elderly cancer patients are a special group, often complicated by a variety of chronic
diseases, which bring serious obstacles to surgery and adjuvant treatment. It is for these
reasons that most patients with high-level evidence-based randomized controlled clinical
trials will be part of these patients. Exclusions ultimately lead to a lack of standards for
the treatment of elderly breast cancer patients, especially the chemotherapy.
Investigators' purpose was to determine whether geriatric assessments are associated with
completion of a chemotherapy course, grade III/IV toxicity or survival in older adults with
breast cancer in older patients.
Investigators want to prospectively enroll breast cancer patients with age ≥70 years. By
recording the pre-treatment baseline laboratory tests and geriatric assessments, through
questionnaires, including Karnofsky performance status(KPS), Eastern Cooperative Oncology
Group(ECOG), Mini Nutritional Assessment(MNA), Activity of daily living(ADL), Instrumental
activities of daily living(IADL), Mini-Mental State Examination(MMSE), Geriatric Depression
Scale(GDS), G-8, Vulnerable Elders Survey-13（VES-13） and FRAIL, Tilburg. Investigators want
to learn the relationship between the geriatric assessments and chemotherapy toxicity,
chemotherapy completion and overall survival. Establish a model for predicting chemotherapy
side effects in old breast cancer patients.