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Stroke clinical trials

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NCT ID: NCT05044208 Recruiting - Atrial Fibrillation Clinical Trials

Echocardiographic Predictors of Atrial Fibrillation

Start date: January 1, 2021
Study type: Observational

This prospective study aims to identify the diagnostic accuracy of echocardiographic predictors of atrial fibrillation in patients with ESUS (embolic stroke of undetermined source) or TIA (transient ischemic attack).

NCT ID: NCT05039697 Recruiting - Stroke, Acute Clinical Trials

Normobaric Hyperoxia Combined With Endovascular Therapy in Patients With Stroke Within 6 Hours of OnsetīŧšLongterm Outcome

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The overall incidence of good outcome for AIS following endovascular treatment is only proximately 50%. Whether NBO was safe and effective to improve acute ischemic stroke prognosis is still unclear. The investigators' hypothesis is thatNBO is a safe and effective strategy to improve longterm outcome in AIS patients undergoing endovascular treatment.

NCT ID: NCT05037721 Recruiting - Oral Health Clinical Trials

Effects of Gargling With Green Tea on Oral Health of Stroke Patients

Start date: July 30, 2021
Phase: N/A
Study type: Interventional

1. Compare the effects of gargling with green tea on the oral health of stroke patients? 2. Compare whether gargling with green tea can reduce halitosis in stroke patients? 3. Compare whether gargling with green tea can reduce plaque index in stroke patients?

NCT ID: NCT05033873 Recruiting - Chronic Stroke Clinical Trials

Universal Exercise Unit Therapy With Sling Exercise Therapy on Lower Limb Kinematics in Chronic Stroke Patients

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

Stroke occurred when blood supply to brain or a part of brain is disturbed due to clot (ischaemic stroke) or due rupture of small vessels (hemorrhagic stroke) in brain and causes bleeding in brain cells. The prevalence of stroke was 1.2 % (1200/100,000) in Pakistan, 3.1% in China and it is 44.29 to 559/100,000 in different parts of the world. Leading cause of stroke is hypertension. The aim of study will be to compare universal exercise unit therapy with sling exercise therapy on lower limb kinematics, disability, balance and quality of life in chronic stroke patients.

NCT ID: NCT05032781 Recruiting - Stroke, Ischemic Clinical Trials

Intra-Arterial Neuroprotective Agents and Cold Saline in Ischemic Stroke Intervention

Start date: June 1, 2021
Phase: Phase 1
Study type: Interventional

Ischemic stroke is the leading cause of long-term disability in the United States. Endovascular intervention with mechanical thrombectomy has become the standard of care for acute large vessel occlusion (LVO) stroke since multiple clinical trials demonstrated improved long-term clinical outcomes with treatment. However, despite high rates of successful vessel recanalization and thus reperfusion of ischemic brain tissue in current practice, many patients continue to suffer debilitating strokes and poor long-term functional outcome. Pharmacologic neuroprotection could potentially present a means of addressing this mismatch in radiologic vs. clinical outcomes by protecting and salvaging damaged brain tissue. Intra-arterial delivery of a cocktail of neuroprotective therapy at the time of endovascular reperfusion would provide immediate, targeted therapy directly to the damaged brain territory. Hypothermia, minocycline and magnesium can target multiple facets of the complex ischemic injury cascade, and have each demonstrated neuroprotection in multiple preclinical models. This is a phase I trial that aims to demonstrate safety and feasibility of administering cold saline, minocycline, and magnesium sulfate intra-arterially immediately after thrombectomy in stroke interventions.

NCT ID: NCT05031403 Recruiting - Stroke Clinical Trials

Development and Application of Tele-Neuro Rehabilitation System

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

Disability due to neurological diseases is increasing in our country and world. With regular physiotherapy and rehabilitation, as well as patients' symptoms are brought under control, their affected functions in daily life are achieved and levels of independence and physical activity increase. Thus, the patients' quality of life and participation in social life is improved and patients are supported in physical, social and psychological terms. In recent years, it has been reported that exercise with telerehabilitation systems increase the compliance and participation of patients to the treatment, and even this system seems as effective as standard rehabilitation practices. Delivering the treatment through telerehabilitation system when that patients cannot receive it in the hospital due to epidemic, restriction, transfer difficulties, personal and environmental limitations will enable patients to receive the rehabilitation services.Telerehabilitation system is frequently encountered in the abroad, but there are limited systems with Turkish version specific to this patient group in our country. The aim of project is to develop and detect the efficiency of a telerehabilitation system which is used to assess, follow and design home-based rehabilitation program among individuals with chronic neurological diseases who have difficulty in participating in physiotherapy and rehabilitation services because of personal or environmental reasons.

NCT ID: NCT05028868 Recruiting - Ischemic Stroke Clinical Trials

Clinical Research of Intravenous Thrombolysis for Ischemic Stroke in Northeast of China

Start date: June 1, 2015
Study type: Observational [Patient Registry]

This research is based on clinic treatment of intravenous thrombolysis for patients with acute ischemic stroke.By building up a database of these patients, the investigators aim to find some significance between groups by analyzing population information, clinical status and such for better evaluation and optimal treatment decision.

NCT ID: NCT05028855 Recruiting - Clinical trials for Cerebrovascular Stroke

Cerebral Autoregulation in Patients With Symptomatic Cerebral Atherosclerotic Stenosis

Start date: January 14, 2017
Study type: Observational [Patient Registry]

In this multi-center prospective observational study within a cohort of symptomatic cerebral atherosclerotic stenosis (sCAS) patients, 850 subjects were planed to be enrolled to explore the relationship between cerebral autoregulation (CA) and stroke recurrence, determine the threshold values of CA parameter for predicting stroke recurrence associated with particular stenosis.

NCT ID: NCT05027178 Recruiting - Stroke Clinical Trials

Stroke Patients Receiving Chiropractic Care Post-rehabilitation

Start date: August 7, 2020
Phase: N/A
Study type: Interventional

The Life University Center for Chiropractic Research is conducting a research study to better understand how 12-weeks of chiropractic care differentially affects the post-rehabilitation brain electrical patterns and body movement patterns of individuals who have experienced hemorrhagic versus ischemic stroke The study will involve visits to the Life University Center for Chiropractic Research (CCR) in midtown Atlanta. During the 12 weeks of focused care, chiropractic visits could be several times a week depending on the care plan. In addition to the chiropractic care, individuals will receive a physical examination and three follow-up assessments. The assessments in the CCR will include a non-invasive evaluation of the brain wave patterns using electroencephalography (EEG), completion of a few surveys, a balance assessment and a movement assessment. Qualified individuals will receive study treatment and care at no cost.

NCT ID: NCT05026359 Recruiting - Clinical trials for Stroke,Rehabilitation,Coordination,Ankle

Evaluation and Rehabilitation for Coordinated Control of Bilateral Ankle Joints in Stroke Patients

Start date: August 14, 2019
Phase: N/A
Study type: Interventional

The coordinated control between the bilateral ankles plays an important role in daily life functions such as walking and balance. The central nervous system damage caused by stroke, in addition to the limitation of the ankle movement on the hemiplegic side and the deterioration of the movement ability, It will seriously affect the coordinated control performance between the bilateral ankle joints, which will cause the majority of stroke patients to have barriers to walking function, and increase the patient's daily care depending on the caregiver. However, there is currently no research on stroke patients, the development of a coordinated control evaluation method with bilateral ankle joints, the use of load-bearing state simulation similar to the real-life bilateral ankle and foot coordination control performance, the establishment of clinical value of bilateral ankle Coordinating the performance parameters of the control evaluation; thus, the clinical doctors can not accurately understand the degree of defect in the bilateral foot and ankle coordination control of the stroke patients, and explore the influence of the bilateral ankle-foot coordination control defect on the daily life function of the stroke patients, and even cannot be based on the evaluation results. The clinical parameters, combined with visual feedback and bilateral rehabilitation advantages of rehabilitation training program, improve the bilateral ankle joint coordination control ability and lower limb function of stroke patients. Therefore, the purpose of this study is to establish an assessment system that can be used to measure the performance of bilateral ankle joint coordination control, to understand the degree of injury in bilateral ankle and foot coordination control, and to analyze the biped coordination parameters and clinical gait performance. The characteristics, and then the design of a double-sided rehabilitation training program combined with visual feedback, is used to improve the bilateral ankle joint coordination control performance and lower limb movement function of stroke patients.