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Stroke, Ischemic clinical trials

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NCT ID: NCT04835740 Completed - Clinical trials for Cerebrovascular Accident

Effects of High-intensity Interval Aerobic Training on Balance, Walking Capacity, and Quality of Life in Patients With Sub-acute Stroke

Start date: October 5, 2020
Phase: N/A
Study type: Interventional

Hemiplegia is one of the most common sequelae of stroke. Stroke is the leading cause of disability in adults all around the world. Stroke survivors can suffer several neurological impairments and deficits which have an important impact on patient's quality of life and which increase the costs for health and social services. After stroke, impairments in ADLs and functional status, deterioration in health related quality of life can be seen. The purpose of this study is to Determine the effect of Aerobic exercise training on Balance, Walking capacity and quality of life in sub-acute stroke.

NCT ID: NCT04825405 Completed - Stroke, Ischemic Clinical Trials

The Use of the Tip Stim Glove Device to Achieve Coordinated Movement of the Human Hand

Start date: July 10, 2019
Phase: N/A
Study type: Interventional

The study was to evaluate the use of the Tip Stim device to achieve coordinated movement and grip force in stroke patients under conditions of active and passive stabilization of the trunk.

NCT ID: NCT04818073 Not yet recruiting - Stroke, Ischemic Clinical Trials

Determinants of the Effectiveness of Robot-assisted Hand Movement Training

Start date: July 2021
Phase: N/A
Study type: Interventional

We would like to investigate the effectiveness of somatosensory input in robot-assisted hand motor rehabilitation after stroke.

NCT ID: NCT04817527 Not yet recruiting - Stroke, Ischemic Clinical Trials

Edaravone Dexborneol for Treatment of Acute Ischemic Stroke With Endovascular Therapy in Extended Time Windows

EXISTENT
Start date: April 1, 2021
Phase: Phase 2
Study type: Interventional

To explore the safety and efficacy of edaravone dexborneol for patients of acute ischemic stroke received endovascular therapy in extended time windows.

NCT ID: NCT04808778 Not yet recruiting - Stroke Clinical Trials

Stroke Prevention in Young Adults With Sickle Cell Anemia

SPIYA
Start date: June 1, 2021
Phase:
Study type: Observational

Sickle cell disease (SCD) is the most common genetic disease, affecting about 25 million people worldwide. Approximately 150,000 Nigerian children are born each year with sickle cell disease (SCD), making it the country with the largest burden of SCD in the world. Recent advancements in care for children with SCA have translated into improved survival of children in both high and low-resource settings. However, more complications of SCD are seen in those who survive to adulthood. Silent cerebral infarcts (SCI) and strokes are among the most devastating complications of SCD, affecting 40% and 10% of children, respectively. The overall goal of this study is to extend the Investigator's successful capacity-building effort in the assessment of neurological morbidity in children with SCD living in northern Nigeria (Kano) to young adults with SCD living in the same region. About 50% of all adults with SCD live in Nigeria. Despite the high prevalence of SCD in Africa, the neurological morbidity is not well characterized, limiting opportunities for primary and secondary stroke prevention strategies. At least 50% of young adults with sickle cell anemia (SCA), the most severe form of the disease, will have SCIs and an estimated 10% will have strokes, based on studies in high-resource settings. In high-resource settings, screening for abnormal transcranial Doppler (TCD) velocities in children with SCA, coupled with regular blood transfusion has resulted in a 92% reduction of relative risk for strokes. Despite this effective strategy, regular blood transfusion therapy does not seem sustainable in sub-Saharan Africa due to shortages and the risk of transfusion transmissible infections. Additionally, there is a lack of evidence-based stroke prevention strategies in young adults with SCA, either in the high-income or in low-resource settings. Based on the foregoing, the Investigators propose to determine the prevalence of neurological injury (overt stroke, transient ischemic attacks, and silent cerebral infarcts) in young adults at the transition age from 16-25 years. The Investigators will also, for the first time, assess conventional risk factors of stroke in the general population to determine whether a different prevention strategy is required to reduce the incidence of neurological injury in this high-risk population.

NCT ID: NCT04804085 Not yet recruiting - Anesthesia Clinical Trials

Anaesthesia for Mechanical Thrombectomy

Start date: June 1, 2021
Phase:
Study type: Observational

Title: Conduct of anaesthesia during acute ischaemic stroke: a retrospective case series of patients undergoing mechanical thrombectomy. Design: This study will be a retrospective consecutive observational case series

NCT ID: NCT04798924 Not yet recruiting - Stroke, Ischemic Clinical Trials

Visual Rehabilitation After Occipital Stroke

Start date: June 15, 2021
Phase: N/A
Study type: Interventional

This research aims to examine changes in plastic potential of the visual system with time from stroke affecting primary visual cortex. We will measure structural and mechanistic aspects of progressive degeneration along the early visual pathways, correlating them with changes in visual performance, and in responsiveness to visual restoration training. This project will advance both scientific knowledge, as well as technical capability and clinical practices for restoring vision and quality of life for people suffering from cortical blindness.

NCT ID: NCT04770363 Recruiting - Stroke, Acute Clinical Trials

Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

This is a randomized clinical trial to study the effect of tDCS in participants with subacute ischemic stroke, the study participants will be randomly assigned into three groups; bihemispheric, unihemispheric and sham group.

NCT ID: NCT04769310 Not yet recruiting - Stroke Clinical Trials

Advanced Cardiac Imaging To Predict Embolic Stroke On Brain MRI: A Pilot Study

Start date: April 2021
Phase: N/A
Study type: Interventional

Demonstrating the pathophysiological link between Left Atrial (LA) and Left Atrial Appendage (LAA) pathology and embolic strokes in non-Atrial Fibrillation (AF) individuals represents a major advance in stroke prevention strategies. Instead of relying on non-specific criteria for stroke risk assessment, the investigators propose to identify individuals with high-risk of embolic stroke using imaging criteria that reflect the underlying pathophysiology of embolic stroke of cardiac origin. the investigators can therefore lay the groundwork for future anticoagulation strategies for stroke prevention beyond AF.

NCT ID: NCT04733742 Not yet recruiting - Stroke, Acute Clinical Trials

Endovascular Treatment With Versus Without Intravenous Tenecteplase in Stroke

BRIDGE-TNK
Start date: December 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this trial is to investigate whether intravenous tenecteplase prior to endovascular treatment can improve 90-day functional outcome of stroke patients with anterior large vessel occlusion who are thrombolysis-eligible within 4.5 hours of symptom onset.