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Stroke clinical trials

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NCT ID: NCT06074081 Enrolling by invitation - Acute Stroke Clinical Trials

Comparison of 4-weeks of Motor Relearning Program and Mirror Therapy in Improving Upper Limb Motor Function in Stroke Patients.

Start date: September 4, 2023
Phase: N/A
Study type: Interventional

Cerebrovascular accident(CVA) or stroke is one of common condition affecting people in developed and underdeveloped countries. MRP is a therapy to regain particular motor function and neglecting accessory movements by engaging cognitive behavior. Mirror therapy enhance functional activities in patient with hemiplegic stroke. For betterment of result high quality methodological studies and larger sample size is required.

NCT ID: NCT06042179 Enrolling by invitation - Stroke Clinical Trials

Frequency vs Error Augmentation Training in Acute Physical Therapy Post Stroke

FEAT
Start date: January 15, 2024
Phase: N/A
Study type: Interventional

The Department of Physical Therapy in conjunction with the Comprehensive Stroke Center at the Medical University of South Carolina (MUSC) seeks support for developing an evidence-based approach for the mobilization of patients within the first 24 hours of admission for an acute stroke and for increasing the frequency and intensity of acute PT services while inpatient. This evidence will prepare physical therapists and guide practice in the delivery of acute stroke mobilization in the hospital setting to optimize length of stay, disposition planning, and enhance long term recovery outcomes. This research hopes to challenge the clinical paradigm regarding the possibility of decreased functional outcomes with early mobilization post stroke. The investigators acknowledge that acute stroke patients may not be able to tolerate an extensive early mobility program but may benefit from shorter more frequent sessions of therapy early in their recovery. Throughout the literature, there are clinical practice guidelines for both the inpatient rehabilitation and outpatient therapy sectors and post stroke recovery. Little is known about the contribution of therapy services in the acute hospital setting and therapy's impact on long term functional gains. The goal of this project is to determine the appropriate dosage of post stroke mobility in the acute care hospital setting.

NCT ID: NCT06040255 Enrolling by invitation - Arteriopathy Clinical Trials

Focal Cerebral Arteriopathy Steroid Trial

FOCAS
Start date: October 1, 2023
Phase: Phase 4
Study type: Interventional

This comparative effectiveness trial (CET) in children with suspected focal cerebral arteriopathy (FCA) presenting with arterial ischemic stroke (AIS) or transient ischemic attack (TIA) will compare the use of early corticosteroid treatment (Arm A) versus delayed/no corticosteroid treatment (Arm B). Delayed corticosteroid treatment is given only for those demonstrating disease progression and is initiated as soon as the progression is detected (at any time after randomization). All participants will also receive standard of care therapy (aspirin and supportive care). Sites will randomize participants 1:1 to Arm A or B. Participants will be enrolled and randomized as soon as possible after their stroke/TIA up until 96 hours following the initial stroke/TIA event.

NCT ID: NCT06038175 Enrolling by invitation - Stroke, Acute Clinical Trials

vHIT Testing for Presentation of Dizziness at a Comprehensive Stroke Center

Start date: January 16, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the sensitivity and specificity of the video head impulse test (vHIT) device, when implemented in the acute ED setting to identify acute ischemic stroke or central pathology vs peripheral vestibular dysfunction in patient's presenting with vertigo. This study will evaluate the implementation of the device, consistency with current diagnostic standards, unnecessary administration of antithrombolytics and will further study the reduction in hospital admissions and overall healthcare costs.

NCT ID: NCT05989945 Enrolling by invitation - Stroke Clinical Trials

HIDRAdenitis Suppurativa and HEART Disease

Start date: August 1, 2023
Phase:
Study type: Observational

In a prospective observational cohort study (n = 250) the investigators aim to assess the correlation between cardiac biomarkers, advanced echocardiography and HS severity and determine whether these are prognostic markers of heart disease in patients suffering from hidradenitis suppurativa (HS).

NCT ID: NCT05970406 Enrolling by invitation - Clinical trials for Dysphagia Following Cerebrovascular Accident

High Intensity Dysphagia Rehab for Acute Ischemic Stroke Patients

Start date: November 30, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine a standardized protocol for swallowing therapy and this protocol's effects on recovery after a stroke

NCT ID: NCT05947773 Enrolling by invitation - Stroke Clinical Trials

Effect of Robotic Treatments on Motor Functions in Subacute Stroke Patients

Start date: July 9, 2023
Phase: N/A
Study type: Interventional

We are conducting a three-group comparative study on stroke patients. The treatment is started in a subacute state and completed in the hospital. The essence of robot-assisted treatments is faster recovery and better learning to walk. The group will do a special walking exercise with a robot. The walking group does the same training, only without robotic assistance. The control group will receive physiotherapy treatments financed by the state. Control examination after 3 weeks.

NCT ID: NCT05920993 Enrolling by invitation - Clinical trials for Cerebrovascular Accident

The Performances and Differences in Tongue Function Between Healthy Adults and Dysphagia in Patients With Stroke in Taiwan

Start date: January 17, 2023
Phase:
Study type: Observational

Cerebrovascular accident makes adults lose the ability to be independent in daily life, and a higher proportion of them will suffer from dysphagia. Previous studies pointed out that the tongue muscle strength of stroke patients is significantly lower than that of healthy adults. Furthermore, the tongue strength of stroke patients with dysphagia is significantly lower than those without dysphagia. Many studies investigated the performance of tongue function in healthy adults or groups with dysphagia caused by different diseases. However, the current research on the performance of tongue function in healthy adults and stroke patients in Taiwan is relatively lacking. Therefore, our purpose of this study is to investigate the performance and differences of tongue function between healthy adults and strokes patients in Taiwan. This study is expected to recruit 32 healthy adults and stroke patients in each group. The two groups will be matched with each other by gender and age (±2 years). In the study, Mann assessment of swallowing ability (MASA) will be used as an assessment tool to distinguish whether the subjects are accompany with dysphagia and the severity of dysphagia. And using Iowa Oral Performance Instrument (IOPI) to measure the value of tongue pressure. Then, analyze whether there are significant differences and the correlations. To provide clinicians with empirical data for early detection and intervention of swallowing.

NCT ID: NCT05905900 Enrolling by invitation - Stroke Clinical Trials

Emergent Prep for IV Dye in Acute Stroke Patients With Allergy

Start date: January 1, 2015
Phase:
Study type: Observational

Our institution implemented a protocol to administer an emergent IV dye preparation for stroke alert patients requiring advanced neuroimaging. The emergent IV dye preparation consists of diphenhydramine 50 mg IV once, famotidine 20 mg IV once, and dexamethasone 10 mg IV once, followed immediately by Computed Tomography (CT) Angiography and/or CT Perfusion.

NCT ID: NCT05885178 Enrolling by invitation - Clinical trials for Stroke, Acute Ischemic

Triage of Patients With Acute Ischemic Stroke Due to Large Vessel Occlusions-1 (TRACK-LVO-1)

TRACK-LVO-1
Start date: January 1, 2018
Phase:
Study type: Observational

The aim of this study is to establish an academic, real-world, single-center, observational registry of consecutive patients hospitalized with acute ischemic stroke (AIS) due to large vessel occlusions (LVO), treated with either endovascular therapy (EVT) or best medical management (BMM).