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Depression clinical trials

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NCT ID: NCT05295069 Completed - Clinical trials for Sleep Quality, Depression, Postnatal Care, Single-Blind Method, Fatigue, Social Support

Can Postpartum Depression Be Prevented With Care

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

This study was designed to eliminate postpartum insomnia and fatigue and reduce the risk of postpartum depression through the maintenance of structural, personal, and social integrity with holistic care under the guidance of Levine's conservation model for primiparous puerperal women who experience fatigue and are at risk of developing depression. : A single-blind pretest-posttest randomized controlled study. Women were called to the hospital on the 7th postpartum day and randomly assigned by a computer program to either the intervention group (n=56) or the control group (n=56). Participants did not know which group they were in.

NCT ID: NCT05292560 Completed - Depression Clinical Trials

The Effectiveness of a Positive Psychology App in the General Population

Start date: April 4, 2022
Phase: N/A
Study type: Interventional

The corona crisis has a negative impact on the mental wellbeing of the Dutch population. Positive psychology exercises (PPOs) can potentially improve mental well-being and reduce mild and moderate psychological complaints. Previous research has shown moderate to large effects of PPOs on well-being in people with reduced wellbeing and psychological symptoms at baseline. The University of Twente developed an app (Training in Positivity; TiP) based on an effective intervention. The goal of this study is to investigate the effectiveness of TiP in the general population in people experiencing reduced mental wellbeing as a result of the corona crisis. People using the app will be compared to a waiting list control group.

NCT ID: NCT05290142 Completed - Depression, Anxiety Clinical Trials

Pre-and-post Study With a Nested Randomized Trial of Digital Training to Teach Problem-solving Counselling in India

Start date: April 6, 2022
Phase: N/A
Study type: Interventional

This study is part of a Wellcome Trust-funded research program in India called PRIDE (PRemIum for aDolEscents, 2016-2022) led by Principal Investigator Prof. Vikram Patel (Harvard Medical School). The goal of PRIDE is to establish a suite of scalable psychosocial interventions for common adolescent mental health problems in India. Following on from earlier studies to develop and evaluate the various PRIDE interventions in school settings, the current study aims to generate evidence on methods to support implementation. We will undertake a pre-and-post study design with a nested randomized controlled trial with the specific aims to: 1. Evaluate the effects of digital training on non-specialists' competency to deliver an evidence-based problem-solving intervention for common adolescent mental health problems 2. Evaluate the incremental effect of digital training with coaching (DT-C) in comparison with self-guided digital training (DT) on non-specialists' competency to deliver an evidence-based problem-solving intervention for common adolescent mental health problems 3. Evaluate the processes affecting the implementation of training interventions in both arms

NCT ID: NCT05285501 Completed - Depression Clinical Trials

Virtual Therapeutic Garden for Depressive Symptoms

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

This study evaluates the addition of virtual therapy intervention in the treatment of depression in the elderly. Half of the participants will receive virtual reality treatment as an addition to physical exercises and psychoeducation, while the other half will receive physical exercises and psychoeducation alone.

NCT ID: NCT05283187 Completed - Stress Clinical Trials

The Effect of Mindfulness-Based Cognitive Therapy Program Applied to Nursing Students

Start date: December 11, 2021
Phase: N/A
Study type: Interventional

Among the stress factors of nursing students are traumatic experiences such as death and encountering a dying patient from the first moments of their education years, fear of making mistakes in the clinic, patient care, not getting enough support from the instructor or clinic staff, and communication problems. Exposure to long-term and uncontrollable stress negatively affects students' professional identity development and health. Students who cannot cope with their stress feel stress at a higher level and as a result they may experience anxiety and depression.It is important for nurse candidates to graduate by being supported in all aspects, both in terms of individual and professional development. For this reason, nursing educators should use effective and innovative interventions to help students recognize the stress they experience and help them reduce stress. Mindfulness-Based Cognitive Therapy Program (MBCT) is one of these programs. Although studies with MBCT are found in the literature, our country In the literature, no randomized controlled studies were found with nursing students. In line with this information, it was thought that mindfulness-based studies were needed. This study was planned to determine the effect of MBCT program on depression, anxiety, stress and cognitive flexibility of nursing students.

NCT ID: NCT05282173 Completed - Depression Clinical Trials

Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa

Siyakhana
Start date: June 8, 2022
Phase: N/A
Study type: Interventional

Poor engagement in care contributes to HIV- and TB-related morbidity and mortality in South Africa (SA). Community health workers (CHWs) are frontline lay health workers who work to re-engage patients who are lost to follow-up (LTFU) in HIV/TB care. Patients with depression and substance use (SU) have a greater likelihood of being LTFU in HIV/TB care, and there is evidence that CHWs may exhibit stigma towards these patients. When CHWs have negative attitudes towards these patients, on average they spend less time with these patients, are less likely to implement evidence-based practices, and deliver less patient-centered care. Therefore, this purpose of this study is to examine the implementation and preliminary effectiveness of a brief training ("Siyakhana"). The purpose of this training is to provide CHWs with psychoeducation, skills, and support around working with HIV/TB patients with depression/SU. The investigators will assess the training's implementation and changes in CHWs' stigma towards HIV/TB patients with depression/SU.

NCT ID: NCT05279989 Completed - Obesity Clinical Trials

Healthy Weight and Stress Management Study

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Approximately 1 in 10 mid-life (age 35-64) Americans have mobility impairing disabilities. People with mobility impairing disabilities are defined using the World Health Organization criteria: community living adults with mobility impairment (e.g., amputation, spinal cord injury). Women with mobility impairing disabilities often struggle with stress, abdominal fat (measured as waist circumference), lack of muscle tissue (measured as handgrip strength) and high cardiometabolic risk. This study investigates the usefulness, acceptability, and effectiveness of two strategies to reduce stress, improve health habits, reduce abdominal fat and increase muscle tissue in mid-life women with mobility impairments. These strategies involve either gentle stretching and strengthening exercises or watching informative videos.

NCT ID: NCT05278572 Completed - Depression Clinical Trials

e-SMART/EST HIV Telehealth Intervention

eSMARTEST
Start date: January 25, 2023
Phase: N/A
Study type: Interventional

The goal of this project is to adapt an evidence-based, enhanced cognitive-behavioral stress management intervention (CSBM+) to target depression among older HIV-positive women in the Bronx, New York. The intervention, "Stress Management and Relaxation Training/Expressive Supportive Therapy" (SMART/EST), demonstrated effectiveness in numerous iterations over 15+ years, including trials with racially diverse HIV-positive women. To meet changing community needs including moving behavioral interventions to telehealth, we will pilot test e-SMART/EST, a teletherapy adaptation with peer support for HIV+ older women.

NCT ID: NCT05271357 Completed - Clinical trials for Major Depressive Disorder

Transcranial Magnetic Stimulation for Depression in Autism Spectrum Conditions

RESTORE
Start date: November 24, 2021
Phase: N/A
Study type: Interventional

In this research study the investigators aim to learn more about the therapeutic effects of a newer form of non-invasive transcranial magnetic stimulation (TMS), called theta burst simulation (TBS), on refractory depression in Autism Spectrum Conditions.

NCT ID: NCT05271084 Completed - Clinical trials for Major Depressive Disorder

Pentoxifylline as an Adjunct to Citalopram in Adult Patients With Major Depressive Disorder

Start date: November 10, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of this study is to test if combining the antidepressant Citalopram with Pentoxifylline (PTX), a medicine with anti-inflammatory and phosphodiesterase inhibitory properties, enhanced antidepressant efficacy in adult patients with major depressive disorder (MDD) when compared to Citalopram alone.