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Depression clinical trials

View clinical trials related to Depression.

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NCT ID: NCT05044546 Not yet recruiting - Depression Clinical Trials

A Behavioral Activation Prenatal and Postpartum Intervention for Depressed Pregnant Smokers

Start date: November 19, 2021
Phase: N/A
Study type: Interventional

This study evaluates a mood management and health and wellness smoking cessation intervention for depressed pregnant smokers during and after birth. This study may help pregnant smokers who are experiencing depression quit smoking and stay smoke-free after their babies are born.

NCT ID: NCT05044455 Not yet recruiting - Clinical trials for Postpartum Depression

Online Peer-Delivered Group CBT for PPD

Start date: October 2021
Phase: N/A
Study type: Interventional

Women who have recovered from Postpartum Depression and are well now, receive training to teach a 9 week Cognitive Behavioural Therapy (CBT) treatment to women who are feeling depressed after giving birth in the last year. Eligible women are randomly assigned to one of two groups. Women in one group will receive a 9 week group CBT treatment delivered online by the trained Peer Leaders. Women in the other group will not receive the CBT group treatment and will continue to receive treatment as usual or regular care for new mothers. Women in both groups will complete online questionnaires three times - when they start the study, nine weeks later and six months after that. Their information will help determine if the CBT treatment is helpful for postpartum depression.

NCT ID: NCT05043818 Not yet recruiting - Clinical trials for Inflammatory Bowel Diseases

A Clinical Study on the Screening of Intestinal Biomarkers in IBD Patients With Depression

Start date: September 2021
Phase:
Study type: Observational

Inflammatory bowel disease (IBD) seriously affects the quality of life of patients. During treatment, it is found that patients are often accompanied by a certain degree of psychological problems, such as depression, sensitivity, introversion, depression, and pessimistic disappointment. Among them, anxiety and depression are the most common. Through prospective observational research, statistics of the incidence of depression in inflammatory bowel disease in our hospital, comparison of the proportions of each subtype, screening of intestinal biomarkers in IBD patients with depression, and observation of inflammatory bowel disease with different The type and quantity of different intestinal flora in patients with severe depression, and the correlation between intestinal flora and depression.

NCT ID: NCT05041647 Not yet recruiting - Depression Clinical Trials

Cannabinoids as a Treatment for Insomnia in Major Depression

CANMDD
Start date: December 1, 2021
Phase: Phase 2
Study type: Interventional

This single-site study is a pilot, three-armed, double-blinded, placebo-controlled randomized controlled trial (RCT) that will determine the feasibility of a definitive RCT investigating the use of cannabis oil as a treatment for insomnia in individuals with MDD. The study will also determine whether standard THC with higher CBD vs lower CBD has a differential impact on insomnia. The study will also analyze other important objective parameters of sleep including total sleep time and sleep efficiency from actigraphy data. Polysomnography data will also be analyzed. In addition, standardized, validated instruments will be used to collect data on severity of depressive symptoms, cognitive functioning biological rhythm disruption, daytime sleepiness, health-related quality of life (HRQoL), healthcare resource utilization, work productivity and activity impairment, as well as other side effects, in order to better understand the potential impact of the use of cannabis oil on these important health outcomes.

NCT ID: NCT05040581 Not yet recruiting - Clinical trials for Postpartum Depression

1 Day Workshops for Preventing PPD

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The aim of this pilot study is to (1) develop a treatment manual for a 1-Day CBT-Based Workshop for preventing postpartum depression that is acceptable to women; (2) recruit 15 women into a pilot workshop and seek their feedback on content, delivery and assessment procedures; and (3) conduct a small pilot randomized controlled trial (n=60) examining the impact of these workshops on rates of PPD when added to care as usual (CAU) more than CAU alone in addition to a 90-minute information session on PPD.

NCT ID: NCT05038085 Not yet recruiting - Clinical trials for Postpartum Depression

Postpartum Depression and Maternal Attachment

Start date: October 2021
Phase: N/A
Study type: Interventional

In terms of postpartum care and depression, follow-up and controls should be continued online in order not to interrupt the follow-up and treatment of women. In this context, in order to prevent the development of postpartum depression and to increase maternal attachment, it is planned to deliver the progressive muscle relaxation exercise and individual health education program that we planned in our study through online applications. This study will be conducted to evaluate the effect of online health education and progressive muscle relaxation exercise program on postpartum depression and maternal attachment.The study was planned as a parallel randomized controlled experimental study conducted in a Family Health Center in Ankara, with a single-center, stratified block randomization (parity: primiparous, multiparous; EPDS score: 0-9, 10-30).The number of pregnant women to be included in the study was calculated as 56.Personal Information Form, Prenatal Attachment Scale, Edinburgh Postpartum Depression Scale and Postpartum Attachment Scale will be used to collect data.

NCT ID: NCT05037214 Completed - Depression Clinical Trials

COVID-19 : Stress Within Hospital Workers

Start date: June 1, 2020
Phase:
Study type: Observational

As of December 2019, the global pandemic of COVID-19 has spread rapidly throughout the world, putting healthcare staff at the frontline. In this context, several factors leading to the appearance of psychiatric symptoms have emerged : work overload, fear of being infected or of infecting, exhaustion… (The Lancet, 2020) Indeed, post-traumatic stress disorder (PTSD), depressive symptoms, anxiety symptoms, insomnia and increased stress have been reported (Rossi et al., 2020). Furthermore, the increased anxiety and depression symptoms and stress associated with the COVID-19 pandemic may increase the risk of suicide in this already high-risk population. For example, suicidal ideation has been reported in up to 5% of healthcare workers in the United States (Young et al., 2021). It is therefore essential to evaluate the incidence of psychiatric disorders (e.g. PTSD, depression, suicide) and their associated risk factors among the hospital staff. To do so, Montpellier University Hospital healthcare staff was asked their mental state during the first wave of COVID-19.

NCT ID: NCT05036720 Not yet recruiting - Depression Clinical Trials

LTP Plus Dads-Partner Inclusive

LTP+Dads
Start date: September 10, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to support and equip fathers and mothers with cognitive behavioral tools and knowledge about child development to be effective in their role as co-parent and partner, leading to improvement in paternal depression. Objectives: - To evaluate the clinical and cost effectiveness of the Learning Through Play+ (LTP + ) intervention in reducing depression in fathers and mothers. - To evaluate the effectiveness of the LTP+ intervention in improving child outcomes. - Process evaluation and identifying challenges in transition to scale up of the intervention across Karachi, Pakistan from the perspective of fathers, mothers, and other stakeholders.

NCT ID: NCT05035563 Recruiting - Covid19 Clinical Trials

Impact of a Communication Strategy in the Prevention of Depressive Symptoms in Patients With Covid-19

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect of an early and integral communication strategy (EICS) versus standard care, on the rate of depressive symptoms at 3 months after discharge from the ICU, in patients with severe Covid-19, their family members and health personnel. Evaluating the rate of depressive symptoms at 3 months after discharge from the ICU, with a) Hospital Anxiety and Depression, b) Posttraumatic Stress Disorder Checklist (S)

NCT ID: NCT05035550 Completed - Depression Clinical Trials

Effects of Open-label Placebos on COVID-related Psychological Health

Start date: February 4, 2021
Phase: N/A
Study type: Interventional

This project aimed to test the efficacy of a telehealth-administered placebo without deception intervention on stress, anxiety, and depression related to the COVID-19 pandemic. Participants were randomized into two groups (open-label placebo vs. no-treatment control). All participants received information on the impact of COVID-19 on psychological health. Participants in the open-label placebo group were instructed to watch an informational video on the beneficial effects of placebos without deception, remotely interact with an experimenter, and take open-label placebo pills twice a day for two weeks. Participants in the no-treatment control group did not receive any intervention. Instead, participants met with an experimenter and reported on their psychological and physical health. The investigators predicted that the placebo without deception group would exhibit substantially reduced stress, depression, and anxiety compared to a no-treatment control group.