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Depression clinical trials

View clinical trials related to Depression.

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NCT ID: NCT05136027 Recruiting - Clinical trials for Resistant Depression, Treatment

TReAtment With Concurrent Exercise in Patients With Resistant Major Depression

TRACE-RMD
Start date: January 30, 2022
Phase: N/A
Study type: Interventional

The aim is to apply an exercise program to study symptomatic and physical changes, as well as to evaluate the improvement in functionality in a resistant depression unit. Sample: 20 patients with the resistant major depressive disorder who will undergo an exercise program. Before and after 12 weeks of intervention, the participants will be assessed with clinical, physical, physiological, biochemical, and functional variables. During 3 months the exercise program will be implemented 2 days per week. It is expected to find an improvement in mood and functionality, as well as changes in physical areas such as blood pressure or body mass index, which are considered predictive factors of cardiovascular disease.

NCT ID: NCT05135897 Recruiting - Healthy Clinical Trials

The Neurobiological Fundaments of Depression and Its Relief Through Neurostimulation Treatments

FundECT
Start date: September 27, 2021
Phase:
Study type: Observational

The study will apply state of the art radiology through advanced magnetic resonance imaging (MRI) techniques to investigate structural and functional brain effects of electroconvulsive therapy (ECT) and repetitive transcranial magnetic stimulation (rTMS).

NCT ID: NCT05134103 Not yet recruiting - Clinical trials for Major Depressive Disorder

Mindbeacon Therapist Assisted Internet Delivered CBT for Depression

Start date: November 2021
Phase: N/A
Study type: Interventional

Utilization of therapist Assisted internet-delivered cognitive behavioural therapy (TAiCBT) for treating depression and anxiety disorders in stepped-care models, such as the UK's Improving Access to Psychological Therapies (IAPT) and the Ontario Structured Psychotherapy Program (SPP), is a potential solution for addressing the treatment gap in mental health. Investigators propose to investigate the effectiveness of Beacon TAiCBT for Depression to demonstrate the potential value of TAiCBT in a stepped care model. Investigators propose to conduct a 12-week pragmatic randomized controlled trial with a 1:1 (iCBT intervention: waiting-list) allocation, for participants referred to the Anxiety and Mood, Prompt Anxiety and Mood, and Trauma Programs at Ontario Shores Centre for Mental Health Sciences and on a waiting-list to receive clinical service. The primary outcome measures will be the Improving Access to Psychological Therapies (IAPT) definitions of Recovery, Reliable Improvement, and Reliable Recovery which are derived using the PHQ-9 and GAD-7 . The PHQ-9 (Depression), GAD-7 (anxiety) and WSAS (functional impairment) will be used as secondary outcome measures for all participants. Over the course of the study, 200 participants will be randomized (iCBT, 100; waiting-list, 100). Statistical analyses will include intention-to-treat analyses to test the interaction effects for the primary outcome measures at discharge/12-weeks and 3, and 12 months post-treatment. It is predicted that participants in the treatment condition will show significantly reduced symptoms of depression related to the waitlist control. It is predicted that this will be maintained through follow up.

NCT ID: NCT05133583 Completed - Clinical trials for Postpartum Depression

Effect of Laughter Yoga Therapy on Postpartum Depression

Start date: April 20, 2021
Phase: N/A
Study type: Interventional

Laughter yoga sessions, stretches and stretches, songs, clapping and body It starts with light warm-up techniques that include movements. These are to break down all kinds of inhibitions and It is aimed at developing the feelings of childlike play. breathing exercises lungs they are ready to laugh and are combined with the following series of laughing exercises. LY In order to provide group dynamics in therapy, the group should consist of at least 5-12 people. provided. Real laughter is often experienced during laughter meditation; it's contagious and may trigger laughter in other people in the group, hence the group can establish greater connections with its members. Laughter yoga sessions are always held at the same time and in the same place to encourage the participation of individuals. has been done.

NCT ID: NCT05127369 Not yet recruiting - Depression Clinical Trials

Clinical Study on the Safety and Efficacy of Dental Pulp Mesenchymal Cells in the Treatment of Depression

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This is a single center phase I / II clinical trial. Randomized, blind and positive drug parallel control were used to evaluate the safety and effectiveness of dental pulp mesenchymal cell injection in the treatment of depression 8 weeks after administration

NCT ID: NCT05123872 Recruiting - Depression Clinical Trials

Transcranial Direct Current Stimulation as Home Treatment in Depression

GSUND_DAHOAM
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

In this one-armed study the feasibility and effectiveness of a home treatment with transcranial direct currect stimulation in depression will be investigated.

NCT ID: NCT05123794 Completed - Depression Clinical Trials

Shortened Depression Assessment Study

Start date: September 1, 2019
Phase:
Study type: Observational

Participants will be asked to fill out an online questionnaire about their demographics information and all 42 items from the Depression Anxiety Stress Scale (DASS-42). A series of machine learning techniques will be applied to the dataset to develop a shortened assessment using the most important demographics and DASS-42 items from the original questionnaire, to predict depression levels indicated by DASS-42.

NCT ID: NCT05122676 Not yet recruiting - Depression Clinical Trials

More Individualized Care: Assessment and Recovery Through Engagement

MI-CARE
Start date: November 2021
Phase: N/A
Study type: Interventional

The MI-CARE trial tests 12 months of telephone-based nurse care management for patients with depressive symptoms who take or have taken opioids at some time. The study tests whether offering nurse support to the patient and their primary care team that addresses these things and related issues can improve patients' health and well-being. Eligible subjects are identified automatically using health system data and randomly assigned 50:50 to either a no-contact usual care arm or to the arm offered the MI-CARE program.

NCT ID: NCT05122429 Completed - Anxiety Clinical Trials

Asynchronous Techniques for the Delivery of Empirically Supported Psychotherapies

Start date: November 6, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to test the feasibility, acceptability and efficacy of methods for delivering mental health support when real-time communication is not possible (e.g. on long duration space flights where communication lags of up to 45 minutes are anticipated). The investigators hypothesize that the two enhanced treatment conditions (i.e., those with therapist support) will outperform the online self-management program without support. The investigators also predict that outcomes for the two enhanced conditions will be comparable to those reported in the literature for in-person psychotherapy programs.

NCT ID: NCT05121129 Recruiting - Clinical trials for Depressive Disorder, Major

Treatment of Major Depression by rTMS on Dorsolateral Prefrontal Cortex: Study of Underlying Mechanisms

DEPSTIM
Start date: October 13, 2021
Phase: N/A
Study type: Interventional

The study aims to evaluate the impact of repeated Transcranial Magnetic Stimulation (rTMS) on underlying neuronal mechanisms of adults suffering from major depression disorder (MDD). Short- and long-term effects are assessed by High-Resolution electroencephalography (HR-EEG) or Magnetic Resonance Imaging (MRI) records, experimental tasks and self-rated scales.