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Obesity clinical trials

View clinical trials related to Obesity.

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NCT ID: NCT06451601 Completed - Obesity Clinical Trials

Intermittent Hypoxia-hyperoxia Therapy in Obese Patients (IHHTOP)

(IHHTOP)
Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Obesity represents the excessive or abnormal accumulation of adipose tissue in the body, which affects health through its association with the risk of developing diabetes mellitus, cardiovascular and pulmonary diseases and hypertension. Obesity can cause significant respiratory changes, so obese patients present pulmonary complications more frequently than individuals with normal weight. Intermittent hypoxia (IH) represents the alternation between repeated episodes of hypoxia interspersed with normoxic episodes. Intermittent hypoxia-hyperoxia is the therapy that uses hyperoxic intervals instead of normoxic ones between hypoxic breathing sessions. This study aimed to evaluate the effectiveness of intermittent hypoxia-hyperoxia therapy among obese patients, focusing on metabolic and respiratory effects. The study aimed to determine if this method could bring benefits in managing or alleviating the complications associated with obesity. A total of 70 obese patients will be recruited and randomized to either the IHHT group or the control group. The intervention group will receive IHHT while the control group will not receive this therapy. All patients will be assessed at baseline and after 2 weeks of treatment using a variety of clinical and functional measures. The study's results will be used to determine whether IHHT benefits the patients who follow it. This study is designed to contribute to the existing body of knowledge on treating obese patients. The results of the study will be of interest to clinicians, researchers, and patients.

NCT ID: NCT06450847 Not yet recruiting - Obesity Clinical Trials

Effect of Soleus Muscle Push Ups on Oxidative Stress and Inflammatory Markers, Soleus Endurance, and Adipocytokines Between Type 2 Diabetic, Overweight/Obese and Normal Weight Individuals.

Start date: June 2024
Phase: N/A
Study type: Interventional

The study aims to investigate the impact of Soleus Push Ups (SPU) on Soleus Muscle endurance, Oxidative Stress Markers, Inflammatory markers and Adipocytokines among people in the United Arab Emirates. This will be a pre-post intervention study with participants divided into three groups: Lean normal metabolic profile, metabolically healthy overweight/obese, and patients with Type 2 Diabetes Mellitus. Assessment of anthropometry and body composition, Soleus Muscle Endurance, blood tests for Inflammatory Markers, Oxidative Stress Markers, and Adipocytokines will be conducted pre and post-intervention.

NCT ID: NCT06448806 Recruiting - Obesity Clinical Trials

Mobile Health (M-health) Intervention to Reduce the Epigenetic Signature in Metabolic Syndrome (MetS)

Start date: June 2024
Phase: N/A
Study type: Interventional

The goal of this interventional study is to learn about the improvement in body composition effects of lifestyle intervention in subjects with metabolic syndrome. The main question it aims to answer is: Does life style intervention lower body fat% and gene methylation levels in subjects with metabolic syndrome? Participants will answer survey questions and get blood and body composition testing done at day 0, at 6 months and 12 months. Keep a diary of their food and activity and the number of times they use mobile health application.

NCT ID: NCT06447246 Not yet recruiting - Childhood Obesity Clinical Trials

Respiratory Effects of Obesity in Children: Longitudinal Consequences After 6 Years of Aging

Start date: June 1, 2024
Phase:
Study type: Observational

The purpose of the study is to re-examine body composition, respiratory function, exercise tolerance, and dyspnea on exertion (DOE) in children with obesity (CWO) and children without obesity (CWOO) who were originally studied as 8-12-year-olds between 2016-2023 (i.e., originally Tanner score ≤ 3; 90 participants; 26 CWOO & 64 CWO). Additionally, the investigators will study the effects of weight loss on body composition, respiratory function, exercise tolerance, and DOE in CWO.

NCT ID: NCT06445413 Recruiting - Obesity Clinical Trials

Tai Chi as a Novel Strategy to Increase Physical Activity Among Adults Pursuing Metabolic and Bariatric Surgery

ACHIEVE
Start date: January 22, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the feasibility and acceptability of a 10-wk hybrid Tai Chi (TC) program with in-person classes and online TC videos among 24 physically inactive adults who are seeking metabolic and bariatric surgery (MBS) in a single-arm trial. The aims are: Aim 1: Feasibility: To evaluate whether TC is feasible, defined as a mean attendance rate of ≥70% in-person TC classes attended. Aim 2: Acceptability: To evaluate whether TC is acceptable, defined as a mean rating of ≥4 across 4 acceptability questionnaire items measured on a 5-point Likert scale (e.g., rate "Tai Chi practice is appealing to me" on a scale from 1 [completely disagree] to 5 [completely agree]). Participants will complete four individual in-person visits where they will complete study assessments and ten weekly group in-person Tai Chi classes where they will practice Tai Chi with up to 5 other study participants. Additionally, they will be asked to practice Tai Chi at home with the aid of instructional online videos and log their practice.

NCT ID: NCT06444646 Recruiting - Obesity Clinical Trials

Differences in Extracellular Vesicles From Adipose Tissue of Individuals With Obesity.

EVO
Start date: February 20, 2023
Phase:
Study type: Observational

Our society is characterized by a strong increase in the prevalence of obesity, which often causes the development of cardiovascular and metabolic diseases such as type 2 diabetes. The way(s) obesity is responsible for these diseases, is still insufficiently understood. This study therefore examines the content of human fat tissue storage location- and cell type-specific extracellular vesicles (EVs) in lean and obese individuals, and the possible connection with sex, insulin sensitivity, and the blood-brain barrier.

NCT ID: NCT06444464 Not yet recruiting - Clinical trials for Overweight and Obesity

The BEE-Power Study (Boosting Exercise for Excellent Pediatric Blood Pressure)

Start date: July 1, 2024
Phase: N/A
Study type: Interventional

The goal of this study is to compare two types of exercises, isometric exercise (like squats and planks) and aerobic exercise (such as running), to see which one is more effective at improving blood pressure in teenagers aged 13 to 17.5 years. The main question the study aims to answer is: - Do the effects of one session of isometric exercise on the blood pressure of adolescents compare to the effects of one session of aerobic exercise? Adolescents diagnosed with high blood pressure may qualify for this study. Participants will be randomly assigned to either a single session of isometric exercise or a single session of aerobic exercise. - Participants will attend 3 study visits in total. - Study visits should be completed within 4 weeks of enrollment. - At the initial visit, samples (example: blood) will be collected and body measurements will be taken. - Participants will be asked to answer questionnaires (diet, growth, and others) - At visit 2, participants will have their blood pressure measured using a 24 hour blood pressure monitor. - At visit 3, participants will participate in a single session of either aerobic or isometric exercise. They will wear a 24-hour blood pressure monitor immediately after the exercise session.

NCT ID: NCT06442696 Completed - Obesity Clinical Trials

Effect Of HCP On Nutrition, Physical Activity And Body Mass Index

Start date: May 15, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test effectiveness of "The Healthy Choices Program, in adolescents. The main question[s] it aims to answer are: 1. Effectiveness of Healthy Choices on Body Mass Index 2. Effectiveness of Healthy Choices on Health Attitude, Nutrition and Physical Activity Knowledge 3. Effectiveness of Healthy Choices on Fruit,vegetable, water consumption

NCT ID: NCT06442371 Recruiting - Obesity Clinical Trials

Additional Effects of Quranic Listening Meditation in Combination With High Intensity Interval Training in Obese Adults

Start date: May 10, 2024
Phase: N/A
Study type: Interventional

To determine the additional effects of Quranic listening meditation, in combination with High-Intensity Interval Training on cardiovascular fitness and mental health in obese adults.

NCT ID: NCT06442202 Completed - Obese Women Clinical Trials

Balanced Nutritional Diet Intervention Among Obese Women

Start date: November 8, 2023
Phase: N/A
Study type: Interventional

Food intake along with the gene are important factors that influence human nutrition status and health. Indonesia has a balanced nutrition diet guide for ideal food consumption. The FTO rs9939609 gene is known to be related to obesity. This study aimed to examine the effect of a balanced nutritional diet intervention on body composition among different single nucleotide polymorphisms (SNP) of the FTO rs9939609 gene in obese young women in Bandung City, West Java, Indonesia.