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Stroke clinical trials

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NCT ID: NCT01560247 Active, not recruiting - Ischemic Stroke Clinical Trials

Percutaneous Recanalization in Ischemic Stroke Management in Europe Observational Registry

PRIISM2
Start date: January 2012
Phase: N/A
Study type: Observational

To determine the revascularization rate, clinical efficacy and safety of the CE-marked MindFrame System in ischemic stroke patients

NCT ID: NCT01550042 Active, not recruiting - Stroke Clinical Trials

Extended Rhythm SCreening for AtRial Fibrillation in Cryptogenic Stroke Patients

SCARF
Start date: September 2011
Phase: N/A
Study type: Observational

Recent studies demonstrated that prolonged rhythm observation increases the detection of atrial fibrillation in patients prior diagnosed as cryptogenic stroke. Detection of atrial fibrillation in these patients has important therapeutic implications for the anticoagulation regimen. However, data on optimal monitoring duration and method of AF detection are limited.

NCT ID: NCT01485354 Active, not recruiting - Stroke Clinical Trials

Upper Arm Training With Armeo Spring for Stroke

Armeo Stroke
Start date: December 2008
Phase: Phase 0
Study type: Interventional

The purpose of this study is: 1. To demonstrate that upper extremity training with the Armeo system with a sensing glove will result in greater functional improvement as measured by clinical functional outcome measures, than Armeo training with grip sensor, in a chronic post-stroke population with impaired upper extremity function. 2. To compare kinematic data following training with grip sensor vs. sensing glove, using data provided by the Armeo system, clinical outcome measures and data derived from the analysis of upper extremity movements using a camera-based motion analysis system.

NCT ID: NCT01445613 Active, not recruiting - Stroke Clinical Trials

Carotid Artery Stenting Outcomes in the Standard Risk Population for Carotid Endarterectomy

CANOPY
Start date: October 2011
Phase: N/A
Study type: Interventional

The objective of the CANOPY trial is to assess the continued safety and effectiveness of the RX Acculink Carotid Stent System under commercial use in subjects at standard risk for adverse events from Carotid Endarterectomy (CEA) enrolled by physicians with a range of carotid stenting experience.

NCT ID: NCT01383512 Active, not recruiting - Subacute Stroke Clinical Trials

Rehabilitation Robotics After a Stroke

REM_AVC
Start date: June 2011
Phase: N/A
Study type: Interventional

Upper limb motor control after a stroke may be improved with rehabilitation robotics at a subacute stage. The aim of this multicenter controled randomized single blind study is to define the place of rehabilitation robotics at this phase of the rehabilitation process. Both groups will realize the same time of rehabilitation. The cost benefit ratio will be compared in each group through medical assessment of improvement and definition of the costs due to the rehabilitation process.

NCT ID: NCT01378637 Active, not recruiting - Stroke Clinical Trials

AMES Treatment of the Impaired Leg in Chronic Stroke Patients

AMES
Start date: January 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this protocol is to determine if individuals who had a stroke more than one year before entering the study and whose ankles remain substantially impaired are able to sense and move the affected leg better after 9-13 weeks of treatment with a robotic therapy device (AMES).

NCT ID: NCT01378468 Active, not recruiting - Clinical trials for First Ischemic Stroke

Prognostic Impact of an Oral Triglyceride Tolerance Test in Patients After Acute Ischemic Stroke

Start date: January 2009
Phase: N/A
Study type: Observational

Non-fasting triglyceride levels are thought to play a role in stroke. The investigators hypothesise that the results of a standardised oral triglyceride tolerance test in the subacute setting (3-7 days) after the first ischaemic stroke are associated with the risk of recurrent stroke within 12 months after the index event.

NCT ID: NCT01334749 Active, not recruiting - Ischemic Stroke Clinical Trials

Observational Study on Determinants of Dementia After Stroke

DEDEMAS
Start date: April 2011
Phase:
Study type: Observational

The primary aim of the DEDEMAS (Determinants of Dementia After Stroke) study is to identify predictors of post stroke dementia (PSD). A particular focus will be on biological markers (neuroimaging, biochemical markers derived from blood) and on interactions between vascular and neurodegenerative mechanisms. For this purpose patients with an acute stroke and without prior dementia will be followed for 10 years. Note: Starting from 01.01.2014 this study is expanded to a multi-centric design funded by the German Center for Neurodegenerative Diseases (The DZNE - Mechanisms of Dementia After Stroke (DEMDAS) Study). This includes the following study sites: DZNE/München - Institute for Stroke and Dementia Research, Klinikum der Universität München (Coordinator); DZNE/Berlin - Neuroscience Research Center - Campus Mitte Charité; DZNE/Bonn - Klinik und Poliklinik für Neurologie, Universitätsklinikum Bonn; DZNE/Göttingen - University Medical Center Göttingen; DZNE/Magdeburg - Universitätsklinikum Magdeburg.

NCT ID: NCT01322607 Active, not recruiting - Stroke Clinical Trials

Task-oriented Training for Stroke: Impact on Function Mobility

TOTS
Start date: July 2011
Phase: N/A
Study type: Interventional

Residual neurological deficits from stroke lead to gait inefficiencies, resulting in an extremely high energy cost of movement and contributing to overall disability and lower quality of life. Therefore, interventions targeting movement economy should be developed for those in the chronic phase of stroke recovery. This study is designed to compare the effect of two distinctly different exercise paradigms (a higher-intensity treadmill training program and a lower-intensity group exercise program) on economy of movement during over-ground walking and activities of daily living, as well as the extent to which gains in muscular strength, muscular endurance, and balance predict changes in movement economy.

NCT ID: NCT01302197 Active, not recruiting - Stroke Clinical Trials

Muscle Atrophy, Physical Performance and Glucose Tolerance Post Stroke

Start date: April 13, 2011
Phase:
Study type: Observational

Stroke, a leading cause of disability in the aging population, increases the risk for diabetes, subsequent stroke recurrence, and cardiovascular disease complications. The downsizing of private and federal health care resources, along with the anticipated increase in stroke rates as our population ages, mandate that alternative strategies be developed to reduce the public health burden of stroke. This pilot study may facilitate our knowledge of the timing of paretic leg muscle atrophy, fiber type shift, and the progression of worsening of glucose tolerance after stroke. Knowledge of the skeletal muscle changes occurring in the sub-acute stroke period is essential to create new guidelines incorporating exercise rehabilitation, much like cardiac rehabilitation, in order to facilitate and improve the health care of veteran stroke survivors.