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Stroke clinical trials

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NCT ID: NCT06152328 Enrolling by invitation - Stroke Clinical Trials

Virtual Reality Based Mirror Therapy

Start date: November 15, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to examine the effectiveness of 3D virtual reality assisted mirror therapy based rehabilitation applications compared to classical methods used in stroke rehabilitation.

NCT ID: NCT06152016 Completed - Stroke Clinical Trials

BE FAST vs. FAST: A Study in the General Public.

Start date: November 20, 2021
Phase: N/A
Study type: Interventional

A randomized, blinded prospective study assessing retention of two stroke mnemonics (BE FAST and FAST) in the general public after receiving brief stroke education. Participants were randomized to one of two education arms and retention was tested at 3 different time intervals.

NCT ID: NCT06150430 Recruiting - Stroke Clinical Trials

An Active Pelvis Orthosis (APO) for Post-stroke Gait Rehabilitation: a Pilot Study

Start date: March 30, 2023
Phase: N/A
Study type: Interventional

The primary objective of this study is to evaluate the safety, reliability and short-term effectiveness of APO-based training to increase the self-selected walking velocity (SSV) of stroke patients. The robotic device is the Active Pelvic Orthosis RT v3.1 (IUVO APO) developed bu IUVO S.r.l.

NCT ID: NCT06149897 Active, not recruiting - Stroke Clinical Trials

Feasibility and Effectiveness of tDCS in the Treatment of Post-stroke Fatigue (EFECTS).

Start date: November 10, 2023
Phase: N/A
Study type: Interventional

This study aims to analyze the use of non-invasive brain stimulation (tDCS) is beneficial for the treatment of post-stroke fatigue.

NCT ID: NCT06149754 Recruiting - Acute Stroke Clinical Trials

BraiN20® Monitoring in Acute Stroke Undergoing Thrombectomy

Start date: September 15, 2023
Study type: Observational

N20 somatosensory evoked potential (SEP) response shows high predictive accuracy of functional recovery in patients with acute ischemic stroke (AIS) undergoing endovascular thrombectomy (EVT). This capacity is independent and even higher than clinical and advanced imaging variables. This study aims to validate BraiN20®, a portable, non-invasive, automatic device to monitor in real-time the presence and characteristics of N20 in AIS patients. 65 patients with AIS and anterior LVO undergoing EVT within 24 hours from onset will be included in three comprehensive stroke centers of Catalonia, Spain. Eligibility criteria are no significant pre-stroke functional dependence, baseline National of Institute of Health Stroke Scale (NIHSS) score equal or higher than 6 points, occlusion (modified Thrombolysis in Cerebral Infarction, (mTICI) 0-1) of the intracranial internal carotid artery (ICA), middle cerebral artery (MCA)-M1 or M2 suitable for EVT per local protocols, without infarct volume restrictions measured by Alberta Stroke Program Early CT (ASPECT) score or by Perfusion Computed Tomography (PCT)/Diffusion Weighted Imaging-Magnetic Resonance Imaging(DWI-MRI) prior to EVT . The primary objective is to confirm an optimal/good reliability of N20 registration before EVT higher than 75% by two blind expert neurophysiologists, assuming a true proportion equal to 87.5%. Secondary endpoints are the predictive accuracy of N20 response recorded by BraiN20® before and after EVT on functional outcome evaluated by the mRS at 7 and 90 days and analyzed by using Receiving Operating Characteristic curves (ROC). A futility interim analysis is planned after the inclusion of 25% population. The trial is sponsored by Time is Brain S.L. and started in September 2023. Primary endpoint results are expected for the first quarter of 2024. BraiN20® could be a useful medical device to predict salvageable brain and functional recovery of patients along the stroke chain.

NCT ID: NCT06149325 Not yet recruiting - Clinical trials for Post-stroke Sensory Deficits at the Hand

Stimulate One Hand to Improve Tactile Perception on the Other

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The study is a comparative study, to show that the administration of RSS stimulation on one hand compared to the administration of strategy Sham stimulation, results in an temporary improvement in the tactile acuity of the other hand in patients with tactile acuity impairment of the hand due to stroke.

NCT ID: NCT06148675 Recruiting - Clinical trials for Stroke, Acute Ischemic

Macrowire for IntracraNial Thrombectomy

Start date: May 25, 2023
Study type: Observational [Patient Registry]

The aim of this study is to develop a multicenter registry of patient data and outcomes for patients undergoing intracranial thrombectomy for acute ischemic stroke secondary to emergent large vessel occlusion with delivery of reperfusion catheter over a novel macrowire (Aristotle Colossus) to perform intracranial mechanical thrombectomy.

NCT ID: NCT06148350 Completed - Stroke, Ischemic Clinical Trials

Frenkel's Exercises for Sub-Acute Ischemic Stroke Patients

Start date: March 5, 2021
Phase: N/A
Study type: Interventional

This single-blinded, randomized controlled was aimed to compare the efficacy of Frenkel's and Conventional Balance Exercises in improving balance and quality of life in patients with subacute ischemic stroke. The participants of Group A received 'Frenkel's Exercises'. In contrast, Group B participants received 'Conventional Balance Exercise' interventions three days/week for 30-60 minutes for four weeks. The data was collected pre and post-treatment on the Berg Balance Scale and Stroke Specific-Quality of Life.

NCT ID: NCT06148285 Recruiting - Clinical trials for Acute Ischemic Stroke

Hyperbaric Oxygen Therapy in Acute Ischemic Stroke Ischemic Stroke Recovery (Pro00061930)

Start date: May 24, 2022
Phase: N/A
Study type: Interventional

This study will critically examine the feasibility, safety and efficacy of HBOT during inpatient rehabilitation (IPR) after acute ischemic stroke measured by non-disruption of 3 hours of daily therapy, frequency of neurological deterioration or complications (seizure, hemorrhage, brain edema), and functional communication, activities of daily living (ADLs) and mobility.

NCT ID: NCT06147674 Not yet recruiting - Stroke Clinical Trials

Evaluation of VQm PHM on Pulmonary Health Parameters for ICU

Start date: January 15, 2024
Study type: Observational

The goal of this observational study is to compare pulmonary health parameter measurements from the VQm PHM™ to existing clinical measurements. The main questions it aims to answer are: - Confirm the performance of non-invasive pulmonary health parameter shunt fraction value found on the VQm PHM™ when compared to available reference measurements. - Confirm the performance of non-invasive pulmonary health parameter pulmonary blood flow, functional residual capacity and physiological dead space found on the VQm PHM™ when compared to available reference measurements.