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Obesity clinical trials

View clinical trials related to Obesity.

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NCT ID: NCT06153654 Recruiting - Adiposity Clinical Trials

Role of the Nasal Environment in Obesity

Start date: July 30, 2021
Study type: Observational

The primary aim of this study is to investigate the nasal environment in obese and lean individuals.

NCT ID: NCT06152536 Recruiting - Obesity Clinical Trials

Effect of a Vegetarian Meal on the Physiology of Insulin Response in Patients With Type 2 Diabetes Mellitus and Obesity

Start date: June 9, 2022
Phase: N/A
Study type: Interventional

The role of diet in determining glucose intolerance and its progression towards T2DM has been extensively investigated. A 2017 meta-analysis showed that a vegetarian diet is inversely associated with the risk of developing diabetes. Vegetarians, with the same baseline risk, are half as likely to develop T2DM than those following an omnivorous diet. Therefore, vegetarian nutrition could have important clinical implications in the dietary management of diabetic patients.

NCT ID: NCT06150248 Recruiting - Obesity Clinical Trials

Effect of Health Education Intervention on Promoting Healthy Lifestyles for Undergraduate Female Students in Saudi Arabia

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

According to the World Health Organization (WHO), Saudi Arabia has seen a more astonishing rise in obesity. Young females have a considerable prevalence of unhealthy dietary practices and lack of knowledge about healthy and energy-dense foods. Additionally, in Saudi Arabia, the levels of physical inactivity ranged from about one-third to as high as 70% of the population. The current study aims to determine the effects of combined health education and motivational message intervention on promoting healthy lifestyles and body composition markers for undergraduate female students who suffer from obesity at Northern Border University in the Kingdom of Saudi Arabia.

NCT ID: NCT06147544 Recruiting - Obesity Clinical Trials

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PB-718 Injection in Chinese Obese Subjects.

Start date: July 6, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The trial is conducted in a single-center, randomized, double-blind, placebo-controlled, dose-increasing design. To evaluate the safety, tolerability, PK characteristics, efficacy and immunogenicity of PB-718 injection in Chinese obese subjects.

NCT ID: NCT06134986 Recruiting - Obesity Clinical Trials

Intermittent Fasting in Adults With Type 1 Diabetes

Start date: November 20, 2023
Phase: N/A
Study type: Interventional

The majority of adults with type 1 diabetes (T1DM) have either overweight or obesity. As such, dietary management has been recommended as an adjunct to insulin treatment to improve glycemic control and facilitate weight loss in patients with T1DM. Daily calorie restriction (CR) is the main diet prescribed to patients with T1DM for weight loss. However, many patients find it difficult to adhere to CR because calorie intake must be vigilantly monitored every day. In light of these problems with CR, another approach that limits timing of food intake, instead of number of calories consumed, has been developed. This diet is called "time restricted eating" (TRE) and involves confining the period of food intake to 6-8 h per day. TRE allows individuals to self-select foods and eat ad libitum during a large part of the day, which greatly increases compliance to these protocols. The simplicity of TRE, its accommodation of dietary preferences, and associated weight loss may translate to improved glycemic measures in patients with T1DM. The present study will be the first randomized controlled trial to compare the effect of TRE versus CR for weight management and improved glycemic control in adults with obesity and T1DM.

NCT ID: NCT06131281 Recruiting - Obesity Clinical Trials

Comparing Reduction With ESD- Versus APC-TORe

Start date: October 2, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare two variations of the same procedure used to assist with weight loss in patients who have a history of Roux-en-Y gastric bypass who have experienced weight regain. The procedure being studied is called the Transoral Outlet Reduction (TORe), and the trial will compare two different ways to complete the TORe procedure. The main question[s] it aims to answer are: - Which variation of the TORe procedure results in more weight loss? - Which variation of the TORe is safer? Participants who are eligible and willing to undergo the TORe procedure to assist with weight loss will have the procedure completed either one of the two ways. All other care will be exactly the same between the two groups. Researchers will compare outcomes between the two procedure variations, looking at which one results in more weight loss, is more successful, and safer.

NCT ID: NCT06120647 Recruiting - Obesity Clinical Trials

Molecular Mechanisms Underpinning Sarcopenic Obesity

Start date: January 28, 2020
Study type: Observational

The coexistence of obesity and sarcopenia results in sarcopenic obesity, a high-risk geriatric condition associated with metabolic perturbations and several co-morbidities. Despite the rising numbers of older adults diagnosed with sarcopenic obesity, few studies have characterized this condition on the muscle cell and systemic level. This study sought to comprehensively assess the influence of sarcopenic obesity on muscle and blood-related parameters and compare it to non-sarocopenic obese and non-sarcopenic lean older adults.

NCT ID: NCT06119295 Recruiting - Obesity Clinical Trials

Investigating the Effects of Altering Portion Size Reduction Awareness on Compensatory Eating Behaviour

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The present study aims to investigate whether energy intake is reduced when participants consume a reduced portion size (15% compared to the 'control' portion), and also to see whether awareness of this reduction affects energy intake.

NCT ID: NCT06117748 Recruiting - Obese Clinical Trials

Volume-Controlled Ventilation and Pressure-Controlled Ventilation Volume Guaranteed in Obese Patients in Laparoscopic-Assisted Surgery

Start date: November 5, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare the efficacy of the pressure controlled ventilation volume-guaranteed (PCV-VG) versus volume-controlled ventilation (VCV) modes as regards lung compliance and oxygenation index in obese patients undergoing laparoscopic assisted surgery especially in Trendelenburg position.

NCT ID: NCT06117631 Recruiting - Metabolic Syndrome Clinical Trials

Project Sueño: Sleep & Understanding Early Nutrition in Obesity

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

The purpose of the study is to understand how mothers think and feel about feeding their babies and putting them to sleep, understand more about programs that can support mothers taking care of babies, and how professionals can be most helpful in helping mothers make decisions about their baby's feeding and sleeping. The overarching goal is to prevent early life obesity and progression to metabolic syndrome in high-risk populations, starting with healthy toddler weights by age 2 years.