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Obesity clinical trials

View clinical trials related to Obesity.

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NCT ID: NCT05692518 Recruiting - Obesity Clinical Trials

DI Bio-fragmentable MAGNET Feasibility Study

Start date: December 19, 2022
Phase: N/A
Study type: Interventional

The purpose of this clinical research study is to evaluate the feasibility of the GT Metabolic Solutions DI Bio-fragmentable Magnetic Anastomosis System (MAGNET System, DI Bio-fragmentable) for creation of a side-by-side anastomosis duodeno-ileostomy in obese adults.

NCT ID: NCT05689632 Recruiting - Obesity Clinical Trials

Vitamins D and K Effects on Vascular Function in Obese Adults.

Start date: July 15, 2022
Phase: N/A
Study type: Interventional

A prospective, randomized, placebo-controlled, double-blind study that aims to evaluate the effects of combined vitamin D3 and K2-MK7 supplementation on vascular function, sympathetic tone, metabolic biomarkers and inflammatory factors in a population of overweight or obese adults and deficient or insufficient serum levels of vitamin D.

NCT ID: NCT05685927 Recruiting - Obesity Clinical Trials

Muscular Deficits of Diabetic Myopathy

Start date: November 1, 2022
Phase:
Study type: Observational

The goal of this observational study is to assess if diabetes and obesity are independently related to functional and structural muscle deficits, and how muscular deficits relate to metabolic properties of diabetes and obesity. All studies will include clinical muscle strength and contractile examinations, functional tests, and MR imaging and spectroscopy techniques. The main questions this project aims to answer are: 1. Is chronic hyperglycemia in type 1 and 2 diabetes associated with functional and structural deficits of skeletal muscles unrelated to the presence of neuropathy? 2. Is obesity associated with functional and structural impairments of skeletal muscles unrelated to the presence of type 2 diabetes ? 3. Does weight loss improve muscle metabolic flexibility and economy and modify skeletal muscle function and structure in obese subjects with and without type 2 diabetes? The project will include three studies, intended to answer the hypotheses listed above: Study 1: Evaluation of functional and structural muscular deficits of diabetic myopathy in relation to prolonged hyperglycemia prior to and 6 months following glycemic improvement in patients with type 1 and 2 diabetes Study 2: Functional and structural muscular deficits in severely obese subjects with and without type 2 diabetes prior to assisted weight loss. Study 3: Changes in functional and structural muscle properties following assisted weight loss in severely obese subjects with and without type 2 diabetes - a 1-year follow-up study.

NCT ID: NCT05685875 Recruiting - Obesity Clinical Trials

Association of Diabetes and Metabolic Syndrome With Severe Malaria in Cameroon

Start date: June 7, 2022
Phase:
Study type: Observational

The aim of this study is to investigate if diabetes, obesity and metabolic syndrome affects disease presentation and severity of malaria in adults in a hospital setting in Cameroon.

NCT ID: NCT05677464 Recruiting - Obesity Clinical Trials

Prospective Multicenter Study With the Endomina® Triangulation Platform

PRETTi
Start date: June 8, 2020
Phase:
Study type: Observational [Patient Registry]

This registry is designed to further assess on a larger scale safety and efficacy of the endomina® device and tissue apposition accessories (TAPES) when used in the frame of "real life" routine clinical practice

NCT ID: NCT05676736 Recruiting - Clinical trials for Obesity, Periodontal Health

Impact of Obesity on Periodontal Health in a Sample of Adult Egyptian Patients: A Comparant Study

Start date: December 1, 2022
Phase:
Study type: Observational

Periodontal disease is defined as "an inflammatory disease of the tooth supportive structure caused by specific microorganisms or groups of specific microorganisms, resulting in progressive destruction of the periodontal ligament and alveolar bone with increased probing depth formation, recession, or both". According to WHO, overweight and obesity are defined as abnormal or excessive fat accumulation that may impair health. Body mass index (BMI) can be considered as an indicator of obesity-related health risks. Obesity was considered a global epidemic problem by the World Health Organization in the 1990s as it has increased internationally over the last decades. Based on review in 2003 the periodontal disease onset, progression and response to therapeutic interventions have been shown to be influenced by several systemic, local and environmental modifying factors and the data collected from the literature suggests that nutritional supplementation has been suggested as a possible influencing factor on periodontal status and wound healing.

NCT ID: NCT05665621 Recruiting - Obesity, Childhood Clinical Trials

The Effects of Strength and Balance Training on Physical Function in Overweight Children

Start date: January 15, 2023
Phase: N/A
Study type: Interventional

The goal of this intervention study is to examine the efficacy of a school-based exercise programme to improve strength and balance in overweight and obese 7-11-year-olds in the UK. The main question[s] it aims to answer are: - Is the school-based exercise programme effective in improving lower limb muscular strength and balance control? - How do increases in strength and balance skills impact physical function, the risk to musculoskeletal health, and physical activity? Participants will attend baseline, post-intervention, and follow-up testing that includes assessment of strength, balance, 3D gait, plantar pressure, physical function and physical activity. The intervention group will take part in physical activity sessions in their school for 1 hour twice a week for a total of 8 weeks. Researchers will compare the intervention group to a control group that will take part in no activity sessions and carry out their normal school and seasonal activities.

NCT ID: NCT05663658 Recruiting - Obesity Clinical Trials

External Oblique Intercostal Plane Block for Laparoscopic Sleeve Gastrectomy

Start date: December 23, 2022
Phase: N/A
Study type: Interventional

The external oblique intercostal (EOI) plane block is a novel approach upper abdominal wall analgesia. The EOI plane block can provide dermatomal sensory blockade of T6-T10 at the anterior axillary line and T6-T9 at the midline. It may be used for postoperative analgesia in obese patients because it is superficial and rapidly identifiable and performed in the supine position. the aim of this study is to investigate the postoperative analgesic efficacy of external oblique intercostal plane block in obese patients undergoing laparoscopic sleeve gastrectomy. Researchers will compare the external oblique intercostal plane block group with control group to see if the EOI plane block is effective for postoperative analgesia in patients undergoing sleeve gastrectomy.

NCT ID: NCT05658991 Recruiting - Obesity Clinical Trials

Electrophysiological Changes With Diet.

Start date: December 11, 2022
Phase: N/A
Study type: Interventional

Dietary habits may affect our body by certain mechanisms, visual sense is one of the most vital human senses that needs special attention in our daily habits.

NCT ID: NCT05657860 Recruiting - Obesity Clinical Trials

Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome

PWS-GXR
Start date: December 17, 2020
Phase: Phase 4
Study type: Interventional

This is a placebo-controlled clinical trial to assess whether Guanfacine Extended Release (GXR) reduces aggression and self injurious behavior in individuals with Prader Willi Syndrome (PWS). In addition, the study will establish the safety of GXR with a specific focus on metabolic effects.