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Obesity clinical trials

View clinical trials related to Obesity.

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NCT ID: NCT05016076 Withdrawn - Obesity Clinical Trials

Multi-Strategy Intervention for Anesthesia Care of Obese Patients A Factorial Randomized Controlled Trial

Start date: May 2022
Phase: N/A
Study type: Interventional

The main objective of this study is to investigate the optimal anesthesia for obese patients undergoing bariatric surgery in the strategies of positive pulmonary ventilation, tracheal intubation technique, hemodynamic monitoring, and postoperative nausea and vomiting (PONV) prophylaxis, as the followed: 1. To evaluate the effectiveness and adverse effect of intravenous dexamethasone for PONV prophylaxis 2. To determine the safe inspiratory pressure to prevent the occurrence of gastric insufflation during facemask ventilation using point-of-care ultrasonography of antrum 3. To compare the effectiveness and safety between video intubating stylet and video laryngoscope in the placement of tracheal tubes 4. To apply minimally invasive CO monitors in guiding goal-directed hemodynamic therapy and assess its impact on major complications and postoperative recovery

NCT ID: NCT04839237 Withdrawn - Obesity Clinical Trials

The Effect and the Pharmacogenomics Study of Liraglutide in Obese Patients

Start date: December 1, 2017
Phase: Phase 2
Study type: Interventional

This studay evaluates the effect of liraglutide in the treatment of obese patients ande the influence of genetic factors on the curative effect.Half of participants will receive Liraglutide alone,while the other half who can not achieving adequate glycaemic control will receive Liraglutide and metformin in combination.

NCT ID: NCT04802005 Withdrawn - Obesity Clinical Trials

Effects of a Short-term Aerobic Interval Exercise Program on Cardiac Fat and Function in Women With Obesity: A Pilot Study

Start date: March 16, 2021
Phase: N/A
Study type: Interventional

The overall goal of this project is to the study the effects of an aerobic interval training program on cardiac fat, and its relationship to cardiac function using cardiac Magnetic Resonance Imaging.

NCT ID: NCT04784338 Withdrawn - Obesity Clinical Trials

Virtual Weight Management Shared Medical Visit

Start date: August 2021
Phase: N/A
Study type: Interventional

Culinary medicine has emerged which provides the practical application of nutrition education through experiential learning. Studies have shown that patients with metabolic syndrome who underwent a series of classes that featured nutrition recommendations and cooking classes had weight loss, and improved cardiac health and blood sugar management. Given the increasing focus on providing remote experiences to minimize contact and risk of infection with Sars-COV2, this pilot study at Boston Medical Center (BMC) will integrate a physician consultation, interactive didactic presentations, nutritious cooking and mind- body exercises. Patients with obesity and metabolic syndrome can attend a virtual shared medical visit series co-taught by a registered dietician and chef and an endocrinologist and weight management specialist. Data will be collected in the form of surveys, phone interviews, chart review, and home monitoring to test both the feasibility of running such an intervention virtually and to explore whether attending this one month program with weekly remote classes/visits improves vitals including weight and blood blood pressure and other small habit changes in patients.

NCT ID: NCT04678323 Withdrawn - Obesity, Childhood Clinical Trials

Pharmacotherapy for Pediatric Obesity: A Phentermine Clinical Trial

Start date: January 2022
Phase: Phase 3
Study type: Interventional

This is a multi-site, randomized, placebo-controlled clinical trial to examine the weight loss efficacy and cardiovascular safety of phentermine 15 mg daily plus lifestyle therapy versus placebo plus lifestyle therapy among 200 adolescents ages ≥10 to <18 years with obesity.

NCT ID: NCT04643301 Withdrawn - Obesity Clinical Trials

Liraglutide for Low-responders After Bariatric Surgery

Start date: December 21, 2020
Phase: N/A
Study type: Interventional

To study the effect of Liraglutide (3.0 mg daily) on 9-month weight loss in low responders 3-months after bariatric surgery.

NCT ID: NCT04543526 Withdrawn - Obesity Clinical Trials

A Post-market Observational Study With the easyEndoTM Universal Linear Cutting Stapler in Standard Laparoscopic and Robot-assisted Laparoscopic Roux-en-Y Gastric Bypass (RYGB) Surgery

Start date: September 1, 2021
Study type: Observational

The primary purpose of this observational registry is to evaluate the safety of the easyEndoTM Universal Linear Cutting Stapler and reloads from Ezisurg Medical when used to create anastomoses during standard and robot-assisted laparoscopic Roux-en-Y Gastric Bypass (RYGB) surgery. Stapler performance during surgery as well as post-operative pain and the clinical efficacy of the procedures will be determined as secondary objectives.

NCT ID: NCT04458415 Withdrawn - Obesity Clinical Trials

The Effect of Traxi Panniculus Retractor on Surgical Time at Non-emergent Cesarean Delivery in Obese Women

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

This is an unblinded, randomized control trial of obese women to evaluate the impact of the Traxi Panniculus Retractor (TPR) on the cesarean operative time and surgical blood loss when compared to silk tape.

NCT ID: NCT04399395 Withdrawn - Obesity Clinical Trials

Naltrexone/Bupropion (Mysimba) to Optimize Weight Outcomes After Obesity Surgery

Start date: November 1, 2020
Phase: Phase 4
Study type: Interventional

Limited/poor weight loss and weight regain are concerns following bariatric surgery, and weight regain may increase the risk for relapse of comorbidities related to obesity. Medications for weight reduction may assist further weight loss, and support weight maintenance, with positive effects on comorbidities. This pilot study will examine the effect of naltrexone/bupropion and lifestyle advice versus lifestyle advice alone for 7 months in patients with a suboptimal weight trajectory (either little weight loss or weight regain) 2 years or later following bariatric surgery.

NCT ID: NCT04335565 Withdrawn - Obesity Clinical Trials

Stevia Extract and Glucose Homeostasis

Start date: March 3, 2020
Phase: N/A
Study type: Interventional

This study aims to assess the effect of stevia extract on postprandial glucose and insulin levels in overweight and obese adults when compared to sugar and water.