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NCT ID: NCT05498818 Not yet recruiting - Healthy Clinical Trials

The Effects of Synaquell on Brain Function of Ice Hockey Players

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

This research is being done to investigate the dietary supplement, Synaquell (TM), for effects on brain function in youth ice hockey players.

NCT ID: NCT05498701 Not yet recruiting - Healthy Clinical Trials

A Study Comparing Two Forms of Tafamidis Without Food and the Amount of Tafamidis in the Blood With Food

Start date: August 25, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this clinical trial is to compare a tablet and a capsule form of tafamidis without food and to assess the amount of tafamidis in blood after taking the tablet form with food. This study is seeking healthy participants over the age of 18. All participants in the study will receive either one tablet or capsule of study medicine on the first day without food, then receive one dose of the other tablet or capsule form 16 days later without food. All participants will then receive one dose of the tablet form with food 16 days later. We will evaluate the amounts in blood for 8 days after taking each dose of the study medicine. Participants will take part in this study for about 96 days. The first visit is a screening visit to ensure that participants are appropriate for the study. Up to 28 days later, eligible participants will visit the study clinic three times (and stay overnight in the clinical research center for 8 nights each time). The study team will also call participants over the phone 28 to 35 days after the last dose of medicine.

NCT ID: NCT05498207 Not yet recruiting - Healthy Clinical Trials

Identification of Biomarkers for Stress Vulnerability and Resilience

Start date: August 2022
Phase: N/A
Study type: Interventional

The purpose of this research study is to understand the biological mechanisms of stress vulnerability (being susceptible to stress) and stress resilience (being able to recover readily from stress), obtain biomarkers (a biological indicator) for stress resilience and to devise strategies for prevention and treatment of stress-related disorders.

NCT ID: NCT05497934 Not yet recruiting - Healthy Clinical Trials

The Effects of Glycerol as an Optical Clearing Agent for Visualization of the Middle Ear

Start date: October 1, 2022
Phase: Phase 1
Study type: Interventional

This study will examine the improvement in middle ear optical coherence tomography imaging from the topical application of glycerol to the tympanic membrane in normal, opaque and post-operative ears

NCT ID: NCT05496634 Recruiting - Healthy Clinical Trials

The Effect of Pilates on Biopsychosocial Characteristics in the Covid-19 Pandemic

Start date: January 5, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to investigation of biopsychosocial characteristics of individuals who do pilates and sedentary individuals during the COVID-19 pandemic. The study was carried out with 2 groups: individuals ages 20-50,participating in a pilates program for 8 weeks (n:27) and sedentary individuals (n:27). Before starting this study, the groups were assessed for biopsychosocial status with the Cognitive Exercise Therapy Approach- Biopsychosocial Questionnaire (CETA-BQ) , for depression levels with the Beck Depression Inventory (BDI), for covid-19 fear levels with the Coronavirus Anxiety Scale, for their sleep quality with the Pittsburg Sleep Quality Index (PSQI), quality of life was assessed with the Nottingham Health Profile (NHP). After the first evaluation, an informative presentation emphasizing the importance of physical activity during the pandemic process was given to all participants. Individuals in the exercise group also participated in pilates sessions that lasted 50 minutes, 2 days a week for 8 weeks. At the end of 8 weeks, all questionnaires were repeated for both groups.

NCT ID: NCT05495373 Completed - Healthy Clinical Trials

Can Saliva be the New Bio-fluid to Monitor Children's Oral Health?

Start date: January 1, 2020
Phase:
Study type: Observational

Background: Salivary diagnosis is an emerging field; the potentially valuable biofluid contains many molecules of the systemic circulation. Still, its profile in health has been scarcely investigated. Aim: This study aimed to characterize the inflammatory profile of healthy children's saliva, and to associate the parameters with clinical diagnoses of caries and gingival inflammation. Study design: Unstimulated saliva was collected from 100 children who underwent clinical dental examinations. The saliva samples were analysed for total protein, specific cytokines (IL-10, IL-8, IL-6 and TNF- α) and bacteria using Bradford assay, ELISA and quantitative real-time polymerase chain reaction, respectively. Salivary values were analysed according to age, plaque index (PI) and gingival index (GI).

NCT ID: NCT05494827 Completed - Healthy Clinical Trials

The Impact of a Regular Borjomi® Consumption on an Anaerobic Performance

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

The effects of 2 weeks 1000 ml daily mineral water Borjomy® consumption of anaerobic performance and acid-base balance in comparison with purified electrolite smart-water and still drinking water.

NCT ID: NCT05493553 Recruiting - Healthy Clinical Trials

Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability

Start date: August 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the short-term effect of a nutritional program consisting of a yerba mate supplement, fiber supplement, and intermittent fasting on glycemic variability in men and women with risk factors for impaired fasting glucose.

NCT ID: NCT05492201 Not yet recruiting - Healthy Clinical Trials

A Study of LY3873862 in Healthy Participants

Start date: August 31, 2022
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the safety and tolerability of LY3873862 when administered either in single or multiple doses in healthy non-Japanese and Japanese participants. The study will also assess how fast LY3873862 gets into the blood stream and how long it takes the body to remove it. The study is open to healthy participants. The study will last up to approximately 40 and 58 days for part A and B, respectively.

NCT ID: NCT05491330 Recruiting - Healthy Clinical Trials

Bioequivalence Study of Nirmatrelvir & Ritonavir From Copaxid 150 +100 mg Tablets (Eva Pharma, Egypt) Versus Paxlovid 150 + 100 mg Film Coated Tablets (Pfizer Europe, Belgium)

Start date: August 2022
Phase: Phase 1
Study type: Interventional

Comparative randomized, single dose, three-way, three-sequence, two treatment, partial replicate, crossover, open-label study to determine the bioequivalence of Nirmatrelvir & Ritonavir From Copaxid 150 +100 mg Tablets (Eva Pharma, Egypt) Versus Paxlovid 150 + 100 mg Film Coated Tablets (Pfizer Europe, Belgium)