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NCT ID: NCT04894656 Suspended - Healthy Clinical Trials

Intestinal Permeability and Gastroparesis

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate potential mechanisms that could lead to the development of a condition known as gastroparesis.

NCT ID: NCT04480736 Suspended - Healthy Clinical Trials

A Study of JNJ-64281802 Against Dengue Serotype 1 Infection in a Dengue Human Challenge Model in Healthy Adult Participants

Start date: July 28, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the antiviral activity of JNJ-64281802 versus placebo in terms of reduction of dengue virus 1 (DENV-1) ribonucleic acid (RNA) viral load (VL).

NCT ID: NCT03165968 Suspended - Healthy Clinical Trials

Test and Evaluation of Non-Invasive Neuro-Assessment Devices (NINAD): NeuroKinetics, Inc, iPAS

Start date: February 22, 2018
Study type: Observational

The long term goal for the Traumatic Injury Research Program (TIRP) is testing of novel devices for the identification and longitudinal assessment of traumatic brain injury (TBI). The Department of Defense (DoD) has now tasked TIRP with the test and evaluation of these devices to assess reliability and validity. The objective of this effort is to test the reliability of the NeuroKinetics Inc (NKI), i-PAS (portable assessment system) device using a test/re-test protocol with healthy controls. The basic research design adopted here is the test/re-test paradigm with three assessments obtained on three separate visits. This will allow the assessment of reliability of both the device and the measure(s) that are computed from the input signals. Participants will be Healthy Controls (HC) as defined in the inclusion exclusion section. In this initial study we will be administering standardized self-report instruments ( Short Form - 36 (SF-36) and the Symptom Checklist-90 (SCL-90r)), standard three-lead electrocardiogram. In addition we will administer the NKI i-PAS specific protocol as delineated by NKI.

NCT ID: NCT03133559 Suspended - Healthy Clinical Trials

Mapping the Human HIV Chronobiome

Start date: April 19, 2017
Study type: Observational

Individuals infected with HIV have a high risk of developing metabolic comorbidities not traditionally associated with the immune dysregulation and deficiency associated with HIV infection and AIDS. Many of these comorbidities in HIV uninfected individuals have been linked to a disordered circadian clock function. The study investigators will further evaluate the circadian clock in HIV infection as a mechanism underlying the metabolic dysregulation in this population.

NCT ID: NCT02502435 Suspended - Healthy Clinical Trials

Human Plasma Fatty Acid Oscillations

Start date: July 2015
Study type: Observational

This study wishes to look at the 24-hour rhythm of certain fats in the blood stream. Recent studies in animals and healthy participants suggest that unusual eating habits may be connected to a change in the 24-hour rhythm of the blood fats the investigators wish to measure. The investigators will ask persons suffering from night eating syndrome, a condition where people eat additional meals throughout the night, to participate in this study. Healthy volunteers who are of the same age and gender, and have a comparable body-mass-index, a number calculated from a person's weight and height, will also be asked to participate. The aim is to learn how the 24-hour rhythm of the blood fats the investigators measure differs between the persons experiencing the night eating episodes and persons who do not.

NCT ID: NCT02091817 Suspended - Healthy Clinical Trials

The Effect of Oxytocin on Face Perception

Start date: November 2013
Phase: Phase 0
Study type: Interventional

The purpose of this study is to determine whether oxytocin affect face perception

NCT ID: NCT01340183 Suspended - Healthy Clinical Trials

Clinical Study Assessing the Safety, Tolerability, and Pharmacokinetics of Intravenous AZD5099 in Healthy Subjects

Start date: May 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of the drug AZD5099 after intravenous administration of single doses in healthy volunteers. The results from this study will form the basis for decisions regarding the future development of AZD5099 as a novel antibiotic for the treatment of serious infections in humans.

NCT ID: NCT00684333 Suspended - Healthy Clinical Trials

Safety and Efficacy of EZ-Ject Injector a Pain-Free Subcutaneous Automatic Injection in Healthy Volunteers

Start date: June 2009
Phase: N/A
Study type: Interventional

Subcutaneous injections are a widely used method for drug delivery. One of its major drawbacks is the pain inflicted during the process. Sindolor has developed the chemical-free EZ-Ject Injector device, based on employing cutaneous local anesthesia on the injection site by an electronic anesthetic system. The purpose of this study is to determine the safety and efficacy of the EZ-Ject for subcutaneous injections.

NCT ID: NCT00623675 Suspended - Healthy Clinical Trials

Heavy Metal Urine Analysis in 20 Healthy Persons Taking Mineralox

Start date: February 2008
Phase: Phase 4
Study type: Interventional

Researchers want to find out if urine heavy metal levels are changed in persons who use Mineralox Basic C™ (Mineralox). Mineralox is a zeolite (clinoptilolite) in combination with Vitamin C. Zeolites are natural supplements (nutraceuticals) that work at the cellular level to remove heavy metals and toxins that are accumulated in every day life safely from the body through the urine. The study doctor will give Mineralox to 20 people in this study to see if it helps with the heavy metal removal from the body.

NCT ID: NCT00275405 Suspended - Healthy Clinical Trials

Effect of Garlic on Inflammatory Mediators

Start date: April 2006
Phase: Phase 4
Study type: Interventional

This research will investigate the effect of garlic oil extract when added to daily diet on inflammatory mediators and blood clotting activation.