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NCT ID: NCT05182047 Withdrawn - Healthy Clinical Trials

A Study of Butamirate Citrate Syrup Versus (vs) Sinecod Syrup (Vanilla) in Adult Healthy Study Volunteers

Start date: March 18, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate bioequivalence with respect to rate and extent of absorption of 2-phenylbuturic acid of the novel medication butamirate citrate syrup 1.5 milligrams per milliliter (mg/mL), and the medication sinecod syrup (vanilla) 1.5 mg/mL after single-dose administration in fasting condition by healthy volunteers.

NCT ID: NCT05159128 Withdrawn - Healthy Clinical Trials

A Study of JNJ-75105186 in Healthy Japanese and Chinese Participants

Start date: November 15, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of JNJ-75105186 after single ascending oral dose administration in healthy Japanese participants and after single oral dose administration in healthy Chinese participants.

NCT ID: NCT04853524 Withdrawn - Healthy Clinical Trials

A Study of JNJ-56136379 in Healthy Participants

Start date: May 6, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the effect of multiple-dose JNJ-56136379 on the single-dose pharmacokinetics (PK) of the combination of bictegravir (BIC), emtricitabine (FTC), tenofovir alafenamide (TAF) in healthy adult participants.

NCT ID: NCT04782661 Withdrawn - Healthy Clinical Trials

A Study of JNJ-70075200 in Healthy Participants

Start date: March 1, 2022
Phase: Phase 1
Study type: Interventional

The purpose of the study is to evaluate safety and tolerability of JNJ-70075200 compared with placebo after administration of single ascending doses of JNJ-70075200 as oral solution (Part 1); multiple ascending doses of JNJ-70075200, administered as oral solution over 14 consecutive days (Part 2); and the option of a single dose of JNJ-70075200 administered as an oral solid formulation (Part 3).

NCT ID: NCT04712006 Withdrawn - Healthy Clinical Trials

A Study of JNJ-64304500 Following Subcutaneous Injection in Healthy Chinese Adult Participants

Start date: May 30, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the pharmacokinetic following single subcutaneous administration of Dose 1 or Dose 2 of JNJ-64304500 in healthy Chinese adult participants.

NCT ID: NCT04393597 Withdrawn - Healthy Clinical Trials

Effects of Food on the Pharmacokinetics of DWJ1458 in Healthy Adults

Start date: May 28, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the food effect on the pharmacokinetics of DWJ1458 after oral administration in healthy volunteers.

NCT ID: NCT04391868 Withdrawn - Healthy Clinical Trials

A Bioequivalence Study of Sildenafil Citrate Orally-Disintegrating Film Dosage Form

Start date: January 30, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the bioequivalence of Sildenafil ODF 50 mg to Viagra® tablet 50 mg under fasted conditions.

NCT ID: NCT04307628 Withdrawn - Healthy Clinical Trials

Response of Gut Microbiota and Cardiometabolic Biomarkers to Consumption of Walnuts

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The researchers will investigate blood and fecal responses in qualified study participants after eating walnuts for 4 weeks compared to not eating walnuts for 4 weeks. The two dietary interventions will be separated by a 4 week washout period. The order of diets will be random; study participants will complete both interventions. Dietary modifications will be part of the study protocol.

NCT ID: NCT04183153 Withdrawn - Healthy Clinical Trials

Neuroendocrine Mapping of the Cerebral Cortex

Start date: August 2020
Phase: N/A
Study type: Interventional

This study is investigating brain regions that share functional connectivity with the hypothalamus and the stimulation of those regions using repetitive transcranial magnetic stimulation (rTMS) to activate the hypothalamus indirectly. The goal of this study is to determine the effectiveness of rTMS in influencing the hypothalamus to better understand the mechanisms between it and the neuroendocrine processes it controls.

NCT ID: NCT04155268 Withdrawn - Healthy Clinical Trials

Flotation-REST for Chronic Pain, Stress, and Sleep

Start date: March 9, 2020
Phase: N/A
Study type: Interventional

This randomized crossover trial aims to examine the effects of Flotation-REST (Reduced, Environmental, Stimulation, Technique/Therapy) compared to laying in a dark room (with reduced environmental stimulation) for those with chronic musculoskeletal pain. This design will allow for comparisons between the two interventions on daily diary assessments of pain, stress, and sleep, both between groups and within individuals.