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NCT ID: NCT04836715 Enrolling by invitation - Healthy Clinical Trials

Prevalence of Visual Dysfunction in Neurological Disorders

Start date: April 2021
Phase:
Study type: Observational

The objective is to determine the prevalence of visual dysfunction in People with Parkinson's Disease (PwP). The investigators will administer the: Visual Impairment in Parkinson's Disease Screen and Revised-Self-Report Assessment of Functional Visual Performance. Patients seen at Fixel Institute and their caregivers will be invited to participate. Responses to the 2 questionnaires will help determine prevalence rates of visual dysfunction in PwP compared to those both with and without other neurological conditions.

NCT ID: NCT04819932 Enrolling by invitation - Healthy Clinical Trials

Pharmacokinetics and Safety of DWJ1451 in Healthy Adults

Start date: March 13, 2021
Phase: Phase 1
Study type: Interventional

Amlodipine, olmesartan, total ezetimibe, rosuvastatin AUCt, Cmax

NCT ID: NCT04691518 Enrolling by invitation - Healthy Clinical Trials

Effect of Intermittent Hypoxia in Healthy Individuals

Start date: November 16, 2016
Phase: N/A
Study type: Interventional

The use of acute intermittent hypoxia (AIH) has been examined in animal and human studies to gain an understanding of its effect on spinal excitability and synaptic strength. Subsequently, the investigators have learned that the use of AIH results in new protein formation and spinal plasticity. The use of acute intermittent hypoxia demonstrates a potential for therapeutic utilization in individuals with neurologic injuries. However, little is known about the effect of AIH in healthy individuals. This work is necessary to understand the mechanisms of AIH-induced plasticity. As such, this research study seeks to evaluate the impact of a single session AIH on upper extremity motor function in healthy individuals.

NCT ID: NCT04643444 Enrolling by invitation - Healthy Clinical Trials

Police COVID-19 Serosurvey

PoliCOV
Start date: February 9, 2021
Phase:
Study type: Observational

The investigators aim to determine the immune status of the employees of the cantonal police of Bern against SARS-CoV-2 over a period of 1 year, and to investigate the risk profile of the study participants and their risk of SARS-CoV-2 exposure in their working and private environments, as well as to evaluate the use of personal protective equipment at potential exposure instances.

NCT ID: NCT04594577 Enrolling by invitation - Healthy Clinical Trials

Clinical Validation of the Fluispotter System for Serial Sampling of Venous Dried Blood Spots

Start date: January 27, 2021
Phase: N/A
Study type: Interventional

This is a prospective, single-centre, non-comparative, non-randomized, open label, clinical investigation of the clinical performance and safety of Fluispotter. The main aim is to validate the clinical performance and safety of the body-worn Fluispotter system used for automated extraction, collection and storage of 20 dried venous dried blood spot samples of 10 µl over the course of 20 hours.

NCT ID: NCT04573101 Enrolling by invitation - Healthy Clinical Trials

EEG Responses to Arabic Music Scales

Start date: February 11, 2019
Phase: N/A
Study type: Interventional

Recent studies showed that various factors can contribute to the efficiency of a music therapy such as the type of music used, the type of instrument, the ethnicity, musical preference of the subjects and many others. Investigators noticed that most of studies and clinical trials, while acknowledging the importance of ethnicity and musical preferences, use the Western Music type in their investigations and practice. While in the Middle East, Music Therapy played a tremendous role in the 10th century since the "scales theory" of the famous Scientists El Farabi and Avicenna, very little countries of the Middle East are investing in scientific studies using Arabic Music as a therapeutic tool. This study will be an electroencephalogram (EEG)-based investigation on correlations of multiple factors that can influence the cortical responses of the subject to the music and self-reported state of emotion and anxiety.

NCT ID: NCT04560816 Enrolling by invitation - Healthy Clinical Trials

A Study of the Cardiac Effects of ALXN1840 in Healthy Adults

Start date: July 24, 2020
Phase: Phase 1
Study type: Interventional

This study will evaluate the effect of a supratherapeutic dose of ALXN1840 on the heart rate (HR)-corrected QT interval (QTc) in healthy adult participants. Moxifloxacin will be used as the active control.

NCT ID: NCT04551599 Enrolling by invitation - Healthy Clinical Trials

A Study of the Effects of Food and Age on Danicopan

Start date: February 21, 2020
Phase: Phase 1
Study type: Interventional

This will be an open-label, 2-part study. Part 1 will be a randomized, 2-sequence, 2-period crossover, food-effect study in healthy young adult participants. Part 2 will be a 1-period age-effect study in healthy elderly male participants.

NCT ID: NCT04551586 Enrolling by invitation - Healthy Clinical Trials

A Study to Assess ACH-0145228 When Administered as Immediate Release Tablet Versus Powder-In-Capsule in Healthy Adult Participants

Start date: March 24, 2020
Phase: Phase 1
Study type: Interventional

This will be an open-label, 3-sequence, 3-period crossover study in healthy adult participants to assess the relative bioavailability of ACH-0145228 when administered as an immediate release tablet versus powder-in-capsule.

NCT ID: NCT04524013 Enrolling by invitation - Healthy Clinical Trials

Swiss National Iodine Survey 2020

Start date: October 1, 2020
Phase:
Study type: Observational

This study will assess iodine status in school aged children and pregnant women is Switzerland. In addition, thyroid status and omega-3 index will be assessed in pregnant women.