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Healthy clinical trials

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NCT ID: NCT03775694 Not yet recruiting - Healthy Clinical Trials

Diffusion MRI-1 Imaging Database

dMRI-1
Start date: January 30, 2019
Phase:
Study type: Observational

The purpose of the dMRI-1 data collection study is to establish a database of clinical images and limited medical history information from patients that have previously received a dMRI scan. All data collected will be de-identified. No safety or effectiveness assessments will be completed.

NCT ID: NCT03775668 Recruiting - Healthy Clinical Trials

Single Dose Mass Balance Study With C14 - Labeled AAI101 in Healthy Male Volunteers

Start date: November 27, 2018
Phase: Phase 1
Study type: Interventional

This is an open-label, single dose, pharmacokinetic (PK) study conducted at 1 study center in the United States (USA). This study will evaluate the absorption, distribution, metabolism, and elimination (ADME), mass balance, safety, and tolerability of a single dose of intravenously administered 14C-AAI101.

NCT ID: NCT03775629 Recruiting - Healthy Clinical Trials

Drug-Drug Interaction Study of "CG100650" in Healthy Volunteers

Start date: December 1, 2018
Phase: Phase 1
Study type: Interventional

This is a randomized, open-label, multiple-dose, parallel, Phase 1 study to compare the pharmacokinetics and to evaluate Drug-Drug Interaction of "CG100650" in healthy volunteers.

NCT ID: NCT03774355 Not yet recruiting - Healthy Clinical Trials

Study to Compare Safety and Pharmacokinetics of "CG1801" and "CGL1802" in Healthy Volunteers

Start date: December 17, 2018
Phase: Phase 1
Study type: Interventional

The objective of this open-label, randomized, 2*2 crossover study is to compare the safety and Pharmacokinetics CG1801 and CGL1802 in Healthy Volunteers.

NCT ID: NCT03774173 Not yet recruiting - Healthy Clinical Trials

Comparison of Aramchol Concentrations With Once or Twice Daily Dosing

Start date: December 2018
Phase: Phase 1
Study type: Interventional

The trial is an open-label, 2-period, randomised, crossover study of the plasma concentrations of aramchol, in which subjects will receive oral doses of aramchol at 300 mg twice daily and 600 mg once daily.

NCT ID: NCT03773549 Not yet recruiting - Healthy Clinical Trials

A Virtual Reality Study of Cognitive Biases in Body Dysmorphic Disorder

Start date: January 2019
Phase:
Study type: Observational

Previous research shows that individuals with Body Dysmorphic Disorder (BDD) misinterpret ambiguous social information in a negative and threatening manner. These erroneous threat appraisals are thought to maintain disorder symptomatology and psychosocial impairment by reinforcing individuals' distorted self-image and ideas of social undesirability. Thus, maladaptive interpretation biases represent an important treatment target for this population; however, existing bias assessments and modification protocols are limited by the hypothetical and distal nature of scenarios and do not capture momentary experiential threat processes. The proposed study seeks to test virtual reality (VR) technology as a novel, in vivo means of eliciting, identifying, and measuring threat interpretation biases in a clinical sample to better understand the fear/threat structure activated during social interactions in BDD. Findings have the potential to enhance our understanding of disorder maintenance and identify more nuanced treatment targets. This study represents a critical first step in the long-term goal of harnessing VR gaming technology to supercharge existing treatment approaches for this debilitating illness.

NCT ID: NCT03773432 Completed - Healthy Clinical Trials

Influence of Meal Schedule: Gender Differences

Start date: August 13, 2018
Phase: N/A
Study type: Interventional

Gender differences in the effect of meal schedule will be studied in a parallel design (10 women and 10 men). In two separate days a probe meal (290 stewed beans, 35 g bread, 100 mL water; 549 Kcal) will be administered in the afternoon, i.e. conventional schedule, and in the morning, i.e. unconventional schedule. The effect of meal schedule will be measured as the differences between the responses on both study days. Participants will be instructed to eat standard dinner the day before and to consume standard breakfast at home the day of the afternoon test. Studies will be conducted in a quiet, isolated room with participants siting on a chair. Perception will be measured at 5 min intervals 10 min before and 20 min after ingestion and at 10 min intervals up to 60 min after the probe meal.

NCT ID: NCT03771794 Recruiting - Healthy Clinical Trials

Heart Rate Variability Augmentation With RR2 Neuromodulation Device

Start date: November 15, 2018
Phase: N/A
Study type: Interventional

Brief Summary: A randomized double-blinded, sham-controlled, crossover study Condition or Disease: impaired autonomic balance measured by heart rate variability

NCT ID: NCT03769779 Not yet recruiting - Healthy Clinical Trials

Evaluation of the Benefits of FloraGLO™ Lutein on Skin Health

Start date: January 2, 2019
Phase: N/A
Study type: Interventional

Therefore, the present study is designed to contribute to the body of literature by investigating the effect of 12-weeks of lutein supplementation on multiple parameters of skin health and appearance in healthy women.

NCT ID: NCT03768609 Not yet recruiting - Healthy Clinical Trials

A Study to Evaluate the Effect of Cyclosporine, a P-Glycoprotein, Breast Cancer Resistance Protein, and Organic-Anion-Transporting Polypeptide Inhibitor, on Pimodivir in Healthy Adults

Start date: December 10, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the effect of a single oral dose of cyclosporine on the pharmacokinetics of a single oral dose of pimodivir when coadministered to healthy adult participants under fasted conditions.