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Depression clinical trials

View clinical trials related to Depression.

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NCT ID: NCT05243264 Completed - Depression Clinical Trials

Empower@Home: A Feasibility Pilot

Start date: February 28, 2022
Phase: N/A
Study type: Interventional

This is an open pilot feasibility study of a novel internet-based cognitive behavioral therapy program for older adults with elevated depressive symptoms. This study will enroll approximately 15 older adults throughout the state of Michigan to better understand the feasibility of the intervention and to probe preliminary effects. The intervention will take approximately 10 weeks to complete. Participants will have lower levels of depression after completing the intervention than before enrollment. Participants will be able to use the internet-based platform with minimal support.

NCT ID: NCT05234970 Completed - Depression, Anxiety Clinical Trials

iWellness Study to Evaluate a Mental Health App for Students

Start date: February 24, 2022
Phase: N/A
Study type: Interventional

The study aims to evaluate whether use of a mobile mental health app improves outcomes of depression and anxiety for students.

NCT ID: NCT05233566 Completed - Clinical trials for Postoperative Depression

Ketamine for Postoperative Avoidance of Depressive Symptoms: The K-PASS Feasibility Trial

K-PASS
Start date: April 25, 2022
Phase: Phase 3
Study type: Interventional

This protocol describes a feasibility trial that will evaluate the feasibility of conducting a full-scale phase 3 trial testing the hypothesis that a postoperative sustained, low-dose ketamine infusion can prevent postoperative depressive symptoms when administered to a targeted population of neurosurgical patients with a history of depression.

NCT ID: NCT05229406 Completed - Depression Clinical Trials

Healthy Minds Program App Dosage

Start date: February 21, 2022
Phase: Phase 1
Study type: Interventional

The study will evaluate the effectiveness of the Healthy Minds Program (HMP) meditation app on participants experiencing depression and/or anxiety. Participants will be assigned to use the HMP app 5- or 15-minutes per day for 4 weeks.

NCT ID: NCT05228457 Completed - Clinical trials for Treatment Resistant Depression

Intensive TMS for Bipolar Depression

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

The research study is being conducted to test whether using high dose spaced theta-burst rTMS (a form of transcranial magnetic stimulation) produces a significant reduction in depressive symptoms compared with sham. This project will recruit patients aged 18-70 with symptoms of bipolar depression who have failed (or not shown signs of improvement) after at least two prior treatments.

NCT ID: NCT05227794 Completed - Depression Clinical Trials

Compassion Training and Mindfulness Training for Social Well-Being and Mental Health

Start date: February 16, 2022
Phase: N/A
Study type: Interventional

Study Design, Aims, and Population: The present study is a three-arm randomized controlled trial (RCT). The primary aim is to test the relative efficacy of two 8-week online interventions - Compassion Cultivation Training (CCT) and Mindfulness-Based Stress Reduction (MBSR) - in promoting diverse university students' social well-being (i.e., reduced loneliness, and enhanced social connectedness and perceived social support) compared to a Waitlist (WL) control group. The secondary aim is to examine the effects of CCT versus MBSR on the mental health of diverse university students compared to the WL group. Mental health is defined in this research as both positive mental health (i.e., happiness, positive emotions, meaning and purpose) and negative mental health (i.e., stress, anxiety, and depression). Additionally, another aim is to enroll 75% students of color and 50% male identifying students, whose social well-being and mental health is currently understudied, to better represent the sociodemographic diversity of the university student population in the literature. Study Rationale: The COVID-19 pandemic triggered widespread disruptions in social connections and relational bonds that robustly support a variety of mental and physical health-protective processes. University students' social well-being may have been especially impacted as universities provide a central context for socialization. At the same time, the pandemic exacerbated a pre-existing rise in cases of mental health conditions in university students. If found effective, online-based CCT and MBSR might serve as scalable psychological interventions to foster social thriving and mental health among diverse university students.

NCT ID: NCT05225987 Completed - Quality of Life Clinical Trials

Effects of Postpartum Nurse Navigation Program

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The study was planned as a two-group parallel randomized controlled experimental study in order to determine the effects of the nurse navigation program developed for mothers in the postpartum period on mothers' self-care power, quality of life, anxiety and depression risks, and physical symptom severity. The study will be carried out in Ankara Etlik Zübeyde Hanım Gynecology Training and Research Hospital. The population of the research will be primiparous mothers who gave birth vaginally in Ankara.

NCT ID: NCT05225025 Completed - Clinical trials for Postpartum Depression

A Pilot Trial of the Reach Out, Stay Strong, Essentials for Mothers of Newborns (ROSE) Postpartum Depression Prevention Intervention in Pregnant Patients Admitted to Strong Hospital

Start date: July 5, 2021
Phase: N/A
Study type: Interventional

This study is a pilot, single-center, randomized controlled trial. It will 1. determine feasibility and acceptability of an evidence-based intervention for prevention of postpartum depression with antepartum patients on a high-risk obstetric unit, 2. determine what adaptations may be needed for an inpatient population 3. determine what retention strategies are most successful and acceptable for this patient population 4. estimate the effect size of an intervention for in-hospital distress, anxiety and depression 5. estimate the effect size of an intervention to reduce the risk of a post-partum depression diagnosis or depressive symptoms.

NCT ID: NCT05223842 Completed - Depression Clinical Trials

Family Promoting Positive Emotions Pilot Study

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Anhedonia is characterized by loss of interest or pleasure. The proposed pilot study would be the first to test an innovative, neuroscience-informed intervention in mothers reporting depressive symptoms and stress to enhance positive emotionality with the goal of preventing anhedonia and associated emotional disturbances in their children. This study will recruit dyads (mothers and their children) for the intervention.

NCT ID: NCT05221567 Completed - Clinical trials for Persistent Depressive Disorder

Intensive Psychotherapy for Chronic Depression

Start date: January 1, 2012
Phase: N/A
Study type: Interventional

The study evaluates whether Intensive psychotherapy show superior effect on chronic depression over TAU