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Depression clinical trials

View clinical trials related to Depression.

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NCT ID: NCT05081596 Not yet recruiting - Depression Clinical Trials

A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD

Start date: October 2021
Phase: N/A
Study type: Interventional

The purpose of the study is to examine the effect of Problem Adaptation Therapy for Pain (PATH-Pain) on cognitive functioning, depression and pain-related disability in 100 older adults with cognitive impairment, chronic pain, and depression. The study will test if PATH-Pain has better cognitive, affective, and functional outcomes than Attention Control Usual Care.

NCT ID: NCT05081167 Recruiting - Clinical trials for Major Depressive Disorder

A Study to Assess the Efficacy and Safety of REL-1017 as Monotherapy for Major Depressive Disorder (MDD)

Start date: June 2, 2021
Phase: Phase 3
Study type: Interventional

This is an outpatient, 2-arm, Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of REL-1017 once daily (QD) as a monotherapy for Major Depressive Disorder.

NCT ID: NCT05078450 Recruiting - Depression Clinical Trials

Mood Lifters Online for Graduate Students and Young Professionals

Start date: September 22, 2021
Phase: N/A
Study type: Interventional

Mood Lifters is a revolutionary mental wellness program that teaches scientifically validated strategies in a supportive group setting. This study will test two new versions of the program designed specifically for graduate students and young professionals. Participants will need to attend 12 hour long virtual weekly meetings on Zoom that focus on helpful mental health strategies and skills. Participants will be encourage to practice what the participants learn at home in order to improve their mood or mental wellness. Additionally, participants will complete a series of measures (approx. 1-1.5 hours) prior to, at the end of the program, 1 month after the program and 6 months after the program.

NCT ID: NCT05078424 Recruiting - Depressive Symptoms Clinical Trials

Cognitive Behavioural Therapy for Youths With Depressive and Anxiety Symptoms in Hong Kong

Start date: September 29, 2021
Phase: N/A
Study type: Interventional

The proposed study is a randomized controlled trial (RCT) that aims to examine the effectiveness of cognitive behavioural therapy in reducing depressive and anxiety symptoms for youths in Hong Kong. It is to be carried out with 120 youths aged 12 - 24 recruited from a series of community-based [email protected] hubs, funded by the Hong Kong Jockey Club Charities Trust. It is designed to improve the youths' abilities/ skills in handling moods to have better emotional management. A written informed consent will be signed by participants. Researchers will perform cognitive behavioural therapy on youths who agree to join the study.

NCT ID: NCT05077644 Recruiting - Clinical trials for Post-partum Depression

Mobile Application in the Management of Mild to Moderate Postpartum Depression (PPD)

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

Primary Objective: Evaluate the user experience with the Stella (TM) app for the management of Postpartum Depression in an observed population for 8 calendar weeks.

NCT ID: NCT05076643 Not yet recruiting - Depression Clinical Trials

Biomarkers, TCM Body Constitution, Dietary Pattern and Psychological Factors in Predicting Depression Among University Students

Start date: January 2022
Study type: Observational

This study aims to determine the predictors of depression among university students in Universiti Tunku Abdul Rahman (UTAR) Sungai Long Campus.

NCT ID: NCT05076214 Not yet recruiting - Clinical trials for Depressive Disorder, Major

Aerobic Versus Leisure Group for Adolescents With Depression

Start date: February 2022
Phase: N/A
Study type: Interventional

The aim is to evaluate aerobic group exercise versus leisure group activities in adolescents with mild to moderate depression. Primary outcome is Children's Depression Rating Scale - Revised (CDRS-R). Secondary outcomes are Clinical Global Impressions - Severity and Improvement scales (CGI), self-reported Quick Inventory of Depression Symptomatology (QIDS- A17-SR), the self-reported Outcome Rating Scale (ORS), clinician rated Children Global Assessment Scale (C-GAS), aerobic capacity (VO2max), muscular strength, body, Body Mass Index (BMI), presence or activity of selected biological markers of neuroprotection and neuroinflammation in blood samples and a cost evaluation rated by parents with Trimbos/iMTA questionnaire for Costs associated with Psychiatric Illness - Child version (Tic-P). Further objectives are qualitative interviews to explore adolescents' experiences of the intervention as well as how their health and lifestyle are influenced and a validation of QIDS- A17-C and QIDS- A17-SR versus CDRS-R will be performed.

NCT ID: NCT05075629 Enrolling by invitation - Depression Clinical Trials

Mental Health in Undergraduate Health Science Students During the Covid-19 Pandemic.

Start date: October 12, 2021
Study type: Observational

A study will be conducted with a quantitative approach with correlational scope, observational analytical study, prospective cross-sectional. The objective is to compare the levels of anxious symptomatology, depressive symptomatology and substance use in university students who were exposed to SARS-CoV-2 with those who were not.

NCT ID: NCT05074901 Recruiting - Depression Clinical Trials

Virtual Agents-based Digital Interventions to Improve Health

Start date: April 22, 2020
Phase: N/A
Study type: Interventional

KANOPEE is a free smartphone application providing screening, follow-up tools and autonomous digital interventions to lower psycho-social stress and its repercussions on sleep and behaviors in the general population. Additionally, KANOPEE permits an adaptation of the intervention to the subject (i.e., an adapted waiting period, frequency, and content), enabling to perform innovative trial conditions. The objective of this long-term study is to evaluate the efficacy of KANOPEE on users among the French general population exposed to psycho-social stress.

NCT ID: NCT05072210 Recruiting - Depression Clinical Trials

Mobile Interventions for the Prevention and Detection of Distress

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

Stress, anxiety, distress and depression are exceptionally high among healthcare providers at the frontline of the COVID-19 pandemic. Knowledge of factors underlying distress and resilience and evidence based interventions to impact the mental wellbeing of frontline healthcare providers is limited. This study will evaluate a novel mobile platform to gather the "distress experience" of healthcare workers at Unity Health Toronto in real time during and after the COVID-19 pandemic, use automated personalized mobile interventions (e.g. routine, sleep, exercise) to nudge active/passive parameters to manage distress.