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Depression clinical trials

View clinical trials related to Depression.

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NCT ID: NCT04846504 Not yet recruiting - Clinical trials for Perinatal Depression

Accelerating Implementation of Mindful Mood Balance for Moms

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The Mindful Mood Balance for Moms (MMBFM) study examines whether using an internet program called Mindful Mood Balance for Moms to deliver Mindfulness Based Cognitive Therapy (MBCT) over an 8-week time period, is effective for reducing depression symptoms among pregnant women with a history of prior depression, and studies the effects of implementation strategies on the reach of the MMBFM program. This study will enroll 470 women from Kaiser Permanente Colorado, Southern California, Georgia. The investigators will compare clinical outcomes between those that receive mental health clinician coaching and those that receive peer coaching throughout the 8-week program. Survey data will be collected at 4 time points throughout the study (baseline, 12 weeks, 3rd trimester, and 3 months postpartum). The cost-effectiveness of both the clinical and peer coaching models at each health care system will be evaluated. For the implementation portion of the study, 30 OB clinics across the 4 health systems will be randomized in equal numbers to provide clinician facing implementation strategies (e.g., recruitment flyers, script pads, electronic medical record prompts) to encourage engagement in the MMBFM program or to usual care where women are only recruited by the study team with no clinician involvement. The primary outcome for testing clinician facing implementation strategies is reach, the percentage of women outreached who initially engage in the MMBFM program.

NCT ID: NCT04846010 Recruiting - Depression Clinical Trials

Recovering Damaged Cells for Sequelae Caused by SARS-CoV-2

Start date: March 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

Post-acute sequelae of SARS-CoV-2 infection can cause multiple system function disorders, and complicated symptoms last for an extended period. The virus can cause this continued infection, or the virus causes immune system function disorder and post-infectious autoimmune disease. The clinical symptoms can be smell loss, taste loss to liver function disorder, kidney function failure, different. No matter how complicated the systems showed in the clinic, all of the symptoms are due to the specific cells being damaged. Our clinical study is focused on recovering the damaged structure and function of the cells that could restore the organ function back to normal or close to normal

NCT ID: NCT04845347 Not yet recruiting - Clinical trials for Post Partum Depression

A Wearable Morning Light Treatment for Postpartum Depression

Start date: May 2021
Phase: N/A
Study type: Interventional

This study will test a consumer health light therapy device (Re-Timer) for women with postpartum depression to better understand how it affects mood and the body clock (also called the circadian clock). Eligible participants will be enrolled and randomized after baseline assessments. In addition to using the Re-Timer light for 5 weeks participants will complete questionnaires at various timepoints, record sleep information, wear an actigraph watch, and provide saliva samples. Additionally, the sleep of the participants' infants will also be monitored using an ankle-worn device (actigraph) and sleep diary at certain time-points as this may influence the mother's mood/sleep, and in turn affect the results. The hypotheses regarding the bright light versus the placebo dim light of the study are: - morning bright light therapy will produce greater improvement from pre- to post-treatment on the Hamilton Rating Scale for Depression - morning bright light therapy will lengthen the Phase angle difference (PAD) and this will mediate change in depression symptoms. - morning bright light therapy will produce greater improvements on self-reported depression symptoms, excessive daytime sleepiness, maternal-infant bonding, social functioning, and sleep-related impairment from pre- to post-treatment.

NCT ID: NCT04844034 Not yet recruiting - Depression Clinical Trials

Effects of a High EPA Multinutrient Supplement on Negative Affect in Young Adults.

Start date: September 2021
Phase: N/A
Study type: Interventional

This is a 24-week-long, randomised, double-blind, placebo-controlled trial exploring the efficacy of a high-EPA multinutrient supplement in the management of high, non-clinical anxiety and depression. The investigators focus on young and healthy, adult university students, who may otherwise not be eligible for pharmacological or cognitive behavioural therapy interventions.

NCT ID: NCT04843462 Not yet recruiting - Clinical trials for Major Depressive Disorder

Add-on Therapy With Edupression.Com® on Therapy Resistant Depressive Patients Treated With Nasal Esketamine Spray

Start date: April 12, 2021
Phase: N/A
Study type: Interventional

Pragmatic clinical trial of an add-on therapy regarding the use of® - a licensed computer based self-help program - on patients with therapy-resistant depression receiving esketamine nasal spray

NCT ID: NCT04842929 Recruiting - Clinical trials for Major Depressive Disorder

Magnetic Randomized Trial in Elderly Depressed

Start date: January 16, 2019
Phase: N/A
Study type: Interventional

Major depressive disorder (MDD) is a common psychiatric condition, mostly treated with antidepressant drugs, which are limited for issues such as refractoriness, adverse effects and drug interactions, especially in the elderly population. In this context, the investigators investigate a non-pharmacological treatment known as recurrent transcranial magnetic stimulation (rTMS) with the theta-burst stimulation (TBS) method for the treatment of geriatric depression. This treatment modality has almost no adverse effects and avoids the risk associated with polypharmacy, providing an interesting alternative to antidepressant treatments. Our aim is to evaluate TBS efficacy in the treatment of geriatric depression in a randomized, double-blind, placebo-controlled clinical trial.

NCT ID: NCT04842461 Recruiting - Depression Clinical Trials

Mental Health, Addictions and Biomarkers in High Athletes Performance

Start date: October 15, 2020
Study type: Observational [Patient Registry]

Sport is a privileged area to promote socialization and health values, such as companionship; a healthy lifestyle; cooperation to achieve common goals, and justice, rejecting unjustified advantages in competition. The concept of fair play is on which the development of those values pivots. From a holistic perspective, it is possible to define fair play, not only as a way to participate but also as a way of projecting people in life with values, assuming a set of behaviors that enhance a healthy and respectful sporting experience with opponents, the companions, the spectators, the referees and all the agents that take part in the sport practice.

NCT ID: NCT04841603 Not yet recruiting - Anxiety Clinical Trials

Brief Digital CBT for Mood and Anxiety Symptoms in Acute Psychiatric Inpatients

Start date: April 2021
Phase: N/A
Study type: Interventional

A randomized control trial examining the feasibility, acceptability, and preliminary efficacy of providing access to the MindShift CBT mobile app via tablet for acute psychiatric inpatients.

NCT ID: NCT04840173 Recruiting - Depressive Symptoms Clinical Trials

Beyond Listening: A Music-based Intervention

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

Study will be conducted to determine if caregivers who use music at home will feel less burden and whether the person they are caring for will demonstrate decreased symptoms of dementia. Caregivers will participate in a series of psycho-educational trainings for six weeks. During this time, caregivers will learn how to use singing, music listening and music with movement with their family member. Caregivers should feel less stressed and a decreased sense of burden. The care recipient should appear happier with less occurrences of depression or restlessness.

NCT ID: NCT04840043 Completed - Clinical trials for Osteopathic Manipulative Treatment

Osteopathic Sympathetic Harmonization and Depression

Start date: October 11, 2017
Phase: N/A
Study type: Interventional

Depression appears to be resistant to the available pharmacological treatments. Autonomic responses accompanied by any psychological stress are sympathetic nervous system (SNS) and neuroendocrine responses are formed by hypothalamus-pituitary-adrenal (HPA) axis. The purpose of this study is; assessment of effectiveness of osteopathic approach on sympathetic nervous system and HPA axis in adolescents with depression.