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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT00463853 Withdrawn - Clinical trials for Coronary Arteriosclerosis

Stem Cell Therapy as Adjunct to Revascularization

STAR
Start date: August 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine whether it is safe to receive an injection of your own bone marrow adult stem cells (autologous BM-MNC) to your heart wall during coronary artery bypass graft (CABG).

NCT ID: NCT00346177 Withdrawn - Clinical trials for Cardiovascular Disease

Stem Cell Study for Patients With Heart Failure

Start date: September 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if cell therapy with your own cells (autologous cells) delivered with a catheter to regions of the heart with poor blood flow will be safe and if it will improve your ejection fraction and heart failure symptoms.

NCT ID: NCT00335101 Withdrawn - Diabetes Mellitus Clinical Trials

Renal Effects of Three Iodinated Contrast Media (CM) in Patients at Risk Undergoing Coronary Angiography

Start date: June 2006
Phase: Phase 4
Study type: Interventional

The study is to evaluate and compare the effects on kidney function of three iodinated contrast media (CM) in patients at risk of kidney damage evaluating serum creatinine (Scr) concentrations up to three days after CM administration.

NCT ID: NCT00326690 Withdrawn - Clinical trials for Coronary Artery Disease

Study Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise Capacity

Start date: November 2005
Phase: N/A
Study type: Interventional

The purpose of the present prospective, randomized study is to investigate the clinical effectiveness of standardized left ventricular reconstruction surgery (LVR). In order to standardize the procedure, the operation will be performed with the Blue Egg, manufactured by BioVentrix, a subsidiary of CHF Technologies, Inc.

NCT ID: NCT00317343 Withdrawn - Coronary Disease Clinical Trials

RIAPRE - Non-interventional Registry of Anticoagulation Treatment (BI-006-IT)

Start date: March 2006
Phase: Phase 4
Study type: Observational

RIAPRE is a non-interventional registry to be settled in Italy with the purpose of collecting data on 600 cases of high risk elective percutaneous coronary intervention (PCI) patients treated with an anticoagulation regime different from unfractionated heparin in monotherapy. About thirty catheterization laboratories will co-operate in this activity. The long term outcome of patients will be taken into consideration. The availability of these data will allow for a better understanding of the therapeutic needs in this area.

NCT ID: NCT00286559 Withdrawn - Clinical trials for Coronary Artery Disease

Assessing Myocardial Blood Flow and Blood Flow Reserve by Transoesophageal Echocardiography (TEE)

Start date: August 2006
Phase: Phase 1/Phase 2
Study type: Interventional

Until today it was not possible to reliably assess the function of a new bypass, i.e., to measure myocardial perfusion. Measuring intramyocardial blood flow directly after revascularisation would greatly improve the assessment of graft function. With transthoracic contrast echocardiography, myocardial perfusion can be reliably assessed, as it has been shown in numerous studies. In the first part of the study the investigators will clarify methodological aspects of contrast echocardiography. In the second part they will analyze the validity of contrast TEE in the operating room.

NCT ID: NCT00286195 Withdrawn - Clinical trials for Coronary Artery Disease

Frontier Registry II Bifurcation Stent System Registry

Start date: December 2004
Phase: Phase 4
Study type: Interventional

To assess the procedural success, performance, 30-day and 6 month clinical outcome of bifurcation stenting, and the six month incidence of clinically indicated target lesion revascularization with the use of the Abbott Vascular MULTI-LINK FRONTIER Coronary Bifurcation Stent System in patients with de novo or restenotic bifurcation lesions.

NCT ID: NCT00276367 Withdrawn - Stroke Clinical Trials

The Impact of Post Discharge One-Time Home Visit: Bridging the Gap Between Hospital and Home.

Start date: October 2006
Phase: N/A
Study type: Observational

A single post-hospital discharge home visit by a geriatric nurse practitioner or geriatric fellow can bridge the gap and ease the transition for elderly frail patients returning home after hospital admission. We believe this intervention will reduce medication errors, ensure follow-up discharge plans, decrease re-hospitalization rates, and decrease morbidity and mortality.

NCT ID: NCT00256035 Withdrawn - Atherosclerosis Clinical Trials

Interleukin-4 (IL-4) as a Marker of Atherosclerosis

Start date: n/a
Phase: N/A
Study type: Interventional

In recent years, medical research into the cause and progression of heart disease due to narrowing and blockage of blood vessels to the heart muscle has improved the understanding of ischemic heart disease. It is now accepted that both the development and later progression with sudden blockage of blood vessels are associated with inflammation, although it remains unknown exactly what triggers this inflammatory process. It is possible that new blood tests which measure markers of inflammation in the bloodstream may be useful to help identify patients at risk of heart damage and assess response to treatment. The study plans to assess a new blood test for a known marker of inflammation (IL-4) in patients with heart disease. The hypothesis of this study is that, the cytokine, IL-4, measured by a new assay, is abnormally elevated in the blood of patients with coronary artery disease. Also hypothesized is that the degree of abnormality of blood IL-4, is related to important clinical events in such patients, including severity of disease, acute complications, and treatment.

NCT ID: NCT00060554 Withdrawn - Clinical trials for Myocardial Infarction

A Safety and Efficacy Trial Evaluating the Use of Fondaparinux in Percutaneous Coronary Intervention (PCI)(63133)(WITHDRAWN)

Start date: April 2003
Phase: Phase 2
Study type: Interventional

The purpose of this research study is to obtain experience in the use of fondaparinux (Arixtra) as compared to heparin when administered to patients who undergo percutaneous coronary intervention (PCI). PCI is a mechanical procedure used to widen the narrowing in a coronary artery in patients with symptomatic coronary artery disease. Fondaparinux and heparin are drugs that inhibit blood clotting.