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Coronary Disease clinical trials

View clinical trials related to Coronary Disease.

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NCT ID: NCT05431309 Not yet recruiting - Clinical trials for Cardiovascular Primary Prevention Strategy

Role of Screening With Coronary Computed Tomography Angiography in Primary Prevention of Coronary Heart Disease

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

The primary objective of this study is to determine whether coronary computed tomography angiography (CCTA) -based coronary heart disease(CHD) prevention strategy will be superior to traditional CHD prevention strategy, in reducing the future risk of CHD which included myocardial infarction, angina, cardiac death, and an emergency/urgent coronary revascularisation procedure, in a community population aged 40 to 69 years with cardiovascular risk factors but no history of cardiovascular disease.

NCT ID: NCT05427786 Not yet recruiting - Clinical trials for Coronary Artery Disease

A Study to Evaluate the Impact of Pre-procedural Intracoronary Nicorandil Injection to PREVENT reductioN Of decREased TIMI FLOW in Patients Who Undergoing Percutaneous Coronary Intervention for the Coronary Artery Disease

Start date: July 1, 2022
Phase: Phase 4
Study type: Interventional

The aim of this study was to determine the effect of intra-coronary administration of nicorandil on the prevention of lowering of coronary blood flow for high-risk plaque lesions defined as the high value of lipid core burden index in patients with coronary artery disease who require stent treatment.

NCT ID: NCT05423379 Not yet recruiting - Clinical trials for Coronary Artery Disease

XIENCE Skypoint Large Vessel Post Approval Study

SPIRIT XLV PAS
Start date: November 4, 2022
Phase:
Study type: Observational

SPIRIT XLV PAS is a prospective, single arm, multi-center, US and OUS post-approval observational study to evaluate the continued safety and effectiveness of the XIENCE Skypoint Large Vessel Everolimus Eluting Coronary Stent System (EECSS) Large Vessel (LV) sizes (diameter 4.5 mm and 5.0 mm) during commercial use in a real-world setting.

NCT ID: NCT05421169 Not yet recruiting - Clinical trials for Coronary Artery Disease

Diastolic Hyperemia-Free Ratio in Patients With CAD

ICE-HEAT
Start date: June 30, 2022
Phase:
Study type: Observational [Patient Registry]

The investigators aimed to identify the value of concordance between the diastolic hyperemia-free ratio (DFR) and fractional flow reserve (FFR) during pre-interventional and post-interventional period using a 0.014" COMET II Pressure Guidewire

NCT ID: NCT05417763 Recruiting - Clinical trials for Coronary Artery Disease

Sensor-equipped Ultrathin Pressure Microcatheter Versus Pressure Wire for Physiological Measurements

SUPREME II
Start date: February 25, 2022
Phase:
Study type: Observational

TruePhysio pressure microcatheter is a novel device for evaluating the functional significance of coronary stenosis, and has been validated in the previous SUPREME study (NCT03541577). This study will further evaluate the safety and efficacy of the physiological indices measured by the TruePhysio pressure microcatheter, with respect to the physiological indices measured by the Pressure Wire.

NCT ID: NCT05415085 Recruiting - Clinical trials for Coronary Artery Disease

Culprit-first in Primary Percutaneous Coronary Intervention

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to assess the impact of culprit-first versus culprit-last percutaneous coronary intervention on the door to balloon time and clinical outcomes in patients with ST-elevation myocardial infarction.

NCT ID: NCT05409209 Active, not recruiting - Clinical trials for Coronary Artery Disease

Carotid Plaque Length to Predict Cardiovascular Events

Start date: January 1, 2017
Phase:
Study type: Observational

This multicenter study involved 5 hospitals (Changhai Hospital; Yueyang Hospital of Shanghai University of Traditional Chinese Medicine; Gongli Hospital; Putuo Hospital of Shanghai University of Traditional Chinese Medicine; No. 904 Hospital of the PLA Joint Logistics Support Force Wuxi). The study enrolled 5000 patients for suspected CAD who referred to coronary angiography from January 2017 through December 2018.

NCT ID: NCT05397392 Recruiting - Heart Failure Clinical Trials

Research on Optimal Diagnosis and Treatment of Cardiorenal Syndrome

ODT-CRS
Start date: January 2016
Phase:
Study type: Observational

To estimate the characteristics, pathogenesis, risk factors and intervention measures for different stages of heart and kidney diseases, and to optimize the curative effects of different treatment schemes

NCT ID: NCT05392491 Not yet recruiting - Clinical trials for Coronary Artery Disease

Brazilian Coronary ARtery Disease

BARD
Start date: June 1, 2022
Phase:
Study type: Observational

Although coronary artery disease may have a stable chronic clinical course, it is known that this reality does not apply to atherosclerotic plaques, they can grow, complicate, stabilize and again start new cycles of growth/destabilization/stabilization or quiescence in the presence or absence of symptoms. While in obstructive coronary lesions there are well-founded guidelines based on multiple clinical studies, in relation to investigation and treatment; on the other hand, in non-obstructive lesions, there are no such guidelines. There are gaps in the knowledge about the prognostic implications of minor injuries and the occurrence of events. This study seeks precisely to fill these knowledge gaps. Of particular relevance are the large number of patients (approximately 10,000 patients) and the long clinical follow-up, that is, in five years.

NCT ID: NCT05391620 Recruiting - Clinical trials for Coronary Artery Disease

The Effect of the 3/7 vs 3X9 Method in Resistance Training on Metabolic Stress in Cardiac Rehabilitation

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

The study proposes to measure the effect of resitance training (RT) (3/7 method) on biological markers of muscle hypertrophy in a cardiac population. 3/7 method consisting of five sets of an increasing number of repetitions (3 to 7) during successive sets and brief inter-set intervals (15 s). This method is compare to 3X9 method, 3 series of 9 repetitions with inter-set (1min).The training exercise consisted of contraction on machine (leg press, triceps press, leg curl, traction, leg extension) with load of ~ 70% of one repetition maximal (1RM). Before these trainings all subject perform HIIT on bicycles (2 min high intensity (80% Wmax) and 2 min low intensity (50% Wmax) during 30 minutes. The investigators collect blood sample before exercice, after HIIT and after RT. It is randomized cross-over study.