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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT04837846 Recruiting - Clinical trials for Coronary Artery Disease

Multicenter Study Into Individualized Scanning for Coronary Artery Disease

Start date: March 29, 2021
Study type: Observational

To evaluate intravascular attenuation of the coronary arteries and image quality in an individualized scan and CM injection protocol whereas both scan and injection parameters are tailored to the individual patient in a North American, European and Asian patient population. To evaluate the radiation dose and contrast media dose of this individualized approach for CCTA in an American, European and Chinese patient population. To evaluate the injection parameters required for an average American, European and Chinese patient population.

NCT ID: NCT04828590 Recruiting - Clinical trials for Coronary Artery Disease

The ADAPT Study: Assessment of the DiAgnostic Performance of DeepVessel FFR in SuspecTed Coronary Artery Disease

Start date: August 10, 2020
Study type: Observational

DEEPVESSEL FFR is a medical device that is designed to extract three- dimensional coronary tree structures and generate computed tomography-derived fraction flow reserve (FFR) values from coronary CT angiogram images. The primary objective of this multi-center clinical validation study is to validate the clinical performance of DEEPVESSEL FFR in identifying patients with myocardial ischemia due to significant obstructive coronary artery diseases.

NCT ID: NCT04827498 Recruiting - Myocardial Ischemia Clinical Trials

Myocardial Ischemia Without Obstructive Coronary Stenoses

Start date: November 8, 2017
Study type: Observational

Coronary-related myocardial ischemia can result from obstructive epicardial stenosis or non-obstructive causes including coronary microcirculatory dysfunction and vasomotor disorders. This prospective study has been created in order to provide knowledge in the field of non-obstructive coronary artery disease.

NCT ID: NCT04827251 Recruiting - Clinical trials for Coronary Artery Disease

Effects of Espresso on Platelet Aggregability in Patients With Coronary Artery Disease

Start date: March 18, 2019
Phase: N/A
Study type: Interventional

Discovered thousands of years ago, coffee is among the most consumed beverages in the world. The relationship between coffee and cardiovascular risk, more specifically coronary artery disease, is controversial. Platelet aggregation and its relationship with coffee is also controversial. The investigators propose this study to evaluate the relationship between coffee and platelet aggregability in patients with coronary artery disease.

NCT ID: NCT04825886 Recruiting - Clinical trials for Coronary Artery Disease

Efficacy and Safety of ZotaRolimus-Eluting Coronary Stent System In Patients With Long Coronary Artery Disease

Start date: December 28, 2017
Study type: Observational [Patient Registry]

This study is to evaluation the efficacy and safety of Zotarolimus-Eluting Stent in patients with long coronary artery disease of 25 mm or longer.

NCT ID: NCT04815928 Recruiting - Clinical trials for Coronary Artery Disease

Registry of Patients That Have Undergone ICA or PCI

Start date: July 1, 2020
Study type: Observational [Patient Registry]

In Invasive Coronary Angiography there are multiple invasively obtained measurements to determine the funcitonal significance of Cornary Artery Disease. In this Registry, patients who have undergone Invasive Coronary Angiography or Percutaneous Coronary Intervention are included to investigate diagnostic and prognostic implications of the invasive measurements.

NCT ID: NCT04814550 Recruiting - Clinical trials for CHD - Coronary Heart Disease

A Prospective, Multicenter, Self-control Clinical Trial on the Effectiveness and Safety of AccuFFRangio Plus

Start date: November 4, 2020
Study type: Observational

This is a prospective, multicenter, self-control clinical trial. 318 patients who need selective operation to evaluate the function of coronary artery were selected and measured with AccuFFRangio Plus and FFR. The data of the experimental group was defined as: FFR value at the distal end of stenosis was obtained by calculating the original X-ray angiographic images of the coronary arteries before operation with the non-invasive blood flow reserve analysis software of Hangzhou ArteryFlow Technology Co., Ltd. The gold standard group data is the clinical measured FFR (clinical gold standard) at the stenosis lesions. It is defined that when the coronary artery reaches the maximum congestion state, the pressure value at the distal end of the stenosis lesions is accurately measured by the guide wire with a pressure sensor, and the ratio value with the coronary mouth pressure is the FFR. By comparing the data of the experimental group and the data of the gold standard group, the effectiveness and safety of the devices in the experimental group were evaluated.

NCT ID: NCT04811976 Recruiting - Clinical trials for Coronary Heart Disease

The Relationship Between Anxiety, Depression and Stent Restenosis After Percutaneous Coronary Intervention

Start date: December 1, 2019
Study type: Observational

Percutaneous coronary intervention is currently one of the effective methods for the treatment of ACS. Unfortunately, the incidence of ISR is as high as 10%-20% at 3-6 months after PCI. So it is necessary to identify the potential risk factors to provide evidence for the prevention of ISR. Current research shows that anxiety and depression are related to the increased risk of major adverse cardiac events and mortality in patients with acute myocardial infarction. But there remains a relative paucity of evidence for the association between anxiety and depression and in-stent restenosis (ISR) .So a retrospective cohort study was conducted in the first hospital of Qinhuangdao in 2015-2020. The patients who underwent coronary angiography 1 year after PCI in our hospital from January 2015 to September 2020 were selected. Patients were divided into ISR and non-ISR groups depending on the follow-up coronary angiography results. Logistic regression model was utilized for analyzing the association of depression and anxiety with the in-stent restenosis (ISR) after PCI.

NCT ID: NCT04811586 Recruiting - Clinical trials for Multivessel Coronary Artery Disease

Efficacy and Safety of One-Stage Hybrid Coronary Revascularization

Start date: December 30, 2020
Phase: N/A
Study type: Interventional

Coronary revascularization could be accomplished either by percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG). PCI with drug-eluting stent (DES) implantation is featured by minimal invasive, low complication and rapid rehabilitation. CABG is characterized by improved long-term, event-free survival attributable to the use of left internal mammary artery (LIMA) graft. Hybrid coronary revascularization (HCR) consists of LIMA bypass to left anterior coronary descending artery (LAD) by minimal invasive direct coronary artery bypass (MIDCAB) and PCI of other stenosed coronary arteries with DES implantation. One-step HCR entails LIMA-LAD anastomosis performed through MIDCAB, immediately followed by PCI for non-LAD lesions, sometimes for diagonal branch, in the hybrid operating room. Limited data are available in comparing one-step HCR to PCI alone for the treatment of multivessel coronary artery disease(MVD). The current EAST-HCR study will investigate the efficacy and safety of one-step HCR for patients with MVD, as comparing to PCI alone.

NCT ID: NCT04808310 Recruiting - Clinical trials for Coronary Artery Disease

QUantitative Flow Ratio Or Angiography for the assessMent of nOn-culprit Lesions

Start date: March 17, 2021
Phase: Phase 4
Study type: Interventional

The aim of this study is to study whether the use of complex 3-dimensional assessment of the severity of a stenosis improves angina and in general cardiovascular outcomes in patients who have residual intermediate coronary artery stenosis following an acute coronary syndrome (ACS) treated with percutaneous coronary intervention (PCI). Goals of the study are: - To investigate whether decision-making based on quantitative flow reserve (QFR) is associated with a decrease in angina 3 months after an ACS - To investigate whether use of QFR is associated with an improved prognosis.