Clinical Trials Logo

Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

Filter by:
  • Recruiting  
  • Page 1 ·  Next »

NCT ID: NCT06453538 Recruiting - Clinical trials for Coronary Artery Disease

Sleep Quality and Sleep-disordered Breathing in Bypass Surgery Patients

UNI-CABG
Start date: February 1, 2023
Phase:
Study type: Observational

To this study is recruiting non- emergency patients to whom are planning to make coronary artery bypass intervention. From all patients are going to examine transthoracic echo, collect blood samples and register overnight sleep polygraph in a qualified sleep laboratory two times; first before cabg and second one after surgery.

NCT ID: NCT06451146 Recruiting - Safety Issues Clinical Trials

Lower Silesian Orbital Atherectomy Registry (LOAR)

LOAR
Start date: May 1, 2022
Phase:
Study type: Observational [Patient Registry]

The Lower Silesian Orbital Atherectomy Registry (LOAR), is an observational registry collecting all consecutive cases of percutaneous coronary intervention (PCI) performed with the support of the Orbital Atherectomy Device due to the presence of calcified lesion in coronary arteries. Data will be collected in two cooperating cardiac centers (Department of Cardiology, The Copper Health Center, Lubin, Poland, and Department of Cardiology, Provincial Specialized Hospital in Legnica, Poland).

NCT ID: NCT06450561 Recruiting - Clinical trials for Acute Coronary Syndrome

Adherence to Secondary Prevention Guidelines for Cardiovascular Risk

Start date: March 1, 2024
Phase:
Study type: Observational

The present observational study aims to determine the degree of adherence to the recommendations of clinical guidelines regarding the prevention of cardiovascular complications in patients hospitalized due to a cardiovascular event.

NCT ID: NCT06437756 Recruiting - Clinical trials for Coronary Artery Disease

Effects of Theraband Resistance Training on Muscle Strength in Coronary Artery Diseases

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

To compare the effects of Theraband Resistance Training with Conventional Resistance Training on muscle strength in coronary artery diseases

NCT ID: NCT06436092 Recruiting - Unstable Angina Clinical Trials

Japanese Coronary Intervention Using Drug Eluting and Perfusion Therapy for Left Main Disease (JDEPTH-LM Registry)

Start date: May 27, 2024
Phase:
Study type: Observational [Patient Registry]

JDEPTH-LM Registry is a prospective, observational, multi-center study designed for the efficacy and safety of Double-effect kissing balloon technique (W-KBT) in left main (LM) bifurcation percutaneous coronary intervention (PCI) using Perfusion balloon (PB) and Drug coated balloon (DCB) in patients with left main coronary artery disease (LMD) with left circumflex artery (LCx) ostium stenosis.

NCT ID: NCT06418100 Recruiting - Clinical trials for Coronary Artery Disease

Recto-intercostal Block for Coronary Artery Bypass Grafting

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

This interventional study aims to learn about the postoperative analgesic efficacy of a new fascial plane block, recto-intercostal fascial plane block, at coronary artery bypass grafting with sternotomy. There will be two groups, one of which will be the control group, and the other will be the study group randomly receiving postoperative recto-intercostal fascial plane block. The main questions it aims to answer are the effect of this new block on postoperative opioid consumption and pain scores. Also, postoperative outcomes related to respiratory ( postoperative oxygenation and atelectasis score), hemodynamic functions ( newly developed arrhythmias), total postanesthesia care unit stay, and hospital stay will be questioned.

NCT ID: NCT06413641 Recruiting - Clinical trials for Coronary Artery Disease

VIsualization of Coronary Artery Disease for Modification of RISK Factors

VICAD-RISK
Start date: March 12, 2024
Phase: N/A
Study type: Interventional

The VICAD-RISK study assesses if visualization of coronary CT angiography images in participants with non-obstructive coronary artery disease will improve LDL lowering, reduce reporting of side effects by cholesterol lowering medications, and modify the coronary artery disease phenotype over 12 months.

NCT ID: NCT06410690 Recruiting - Clinical trials for Coronary Artery Disease

Trustworthy, Integrated Artificial Intelligence Tools for Predicting High-risk CORonary PlaqueS

AI-CORPS
Start date: May 22, 2023
Phase:
Study type: Observational

Coronary artery disease (CAD) is among the leading cause of death and disability. Identification of patients at high risk of cardiovascular events is pivotal. However, current risk stratification based on imaging and known biomarkers is suboptimal. The objective of this proposal is to develop a multicriteria decision model for non-invasive assessment of vulnerable atherosclerotic patients and to evaluate its ability to predict the occurrence of an adverse event in intermediate-to-high risk patients with suspected or known CAD. The planned workflow includes a first step using a retrospective cohort of patients undergoing clinically indicated coronary angiography (CCTA) to develop an integrated application for automatic coronary artery segmentation, quantitative plaque analysis, biomechanics and fluid dynamics, based on machine learning, radiomics and computational analysis approaches and validated against the reference standard for each tool. The second step will apply this new methodology to a larger retrospective cohort of patients with the integration of genomic biomarker assessment to derive the most accurate risk stratification model to properly identify vulnerable patients and vulnerable plaques with respect to outcome. Finally, in the third step, the derived predictive model will be prospectively validated in an independent cohort of patients from an ongoing study (CTP-PRO study) to assess the robustness and accuracy of the proposed solution.

NCT ID: NCT06399328 Recruiting - Clinical trials for Coronary Atherosclerosis of Native Coronary Artery

Cardiovascular Risk Stratification on the Basis of Surface Enhanced Raman Spectroscopy

CRUISERS
Start date: September 15, 2023
Phase:
Study type: Observational [Patient Registry]

In the modern population, mortality and disability from cardiovascular diseases is predominant and is realized as a major medical and social problem. The study of mechanisms of development of age-related diseases, such as coronary heart disease (CHD), has demonstrated multiple qualitative and quantitative changes of metabolites in biological fluids of the body - blood, in the vascular wall, as well as in the tissues of vital organs. In routine clinical practice only about a dozen metabolic parameters are determined by standard laboratory methods. The proposed approach belongs to a new scientific direction , wich development is aimed at individualization of approaches to risk stratification of cardiovascular diseases and their complications. The data obtained in this project will allow to create a base of medical knowledge about spectral characteristics of blood serum, which most fully reflect the metabolic profile associated with atherosclerosis of coronary arteries. Researchers offer so-called multiplex diagnostics when multiple parameters of a biological object obtained by serum biochemical analysis and optical scattering analysis are used. Recognition of this big data is possible only by methods of mathematical analysis, which can take into account the degree of deviations, their directionality in each point of the spectral characteristic. Until recently, the standard setup for Raman light scattering studies had significant dimensions. The high cost of such installations made it difficult to widely use the method of optical spectroscopy for rapid analysis of medical objects. In recent years, the situation on the market of scientific instrumentation has changed radically, which allowed to significantly reduce and cheapen all components of Raman installations.This simplification and cheapening allows to bring optical research in medicine (optical biopsy) to a new level of use, directly into clinical laboratories. Novelty: This area of research belongs to high-tech and is very little represented in Europe. The prospect of using Surface Enhanced Raman spectroscopy (SERS) to determine subclinical lesions of coronary arteries and for risk stratification of diseases associated with atherosclerosis is quite unique and wasn't explored yet.

NCT ID: NCT06397820 Recruiting - Clinical trials for Coronary Artery Disease

Relation Between AI-QCA and Cardiac PET

AI-CARPET
Start date: September 1, 2021
Phase:
Study type: Observational

The aim of the study is to evaluate the clinical implications of artificial Intelligence (AI)-assisted quantitative coronary angiography (QCA) and positron emission tomography (PET)-derived myocardial blood flow in clinically indicated patients.