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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT06237673 Enrolling by invitation - Clinical trials for Coronary Artery Disease

The "CAD-Man" EXTEND Study

CAD-Man-EXTEND
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

CAD-Man Extend is the long-term follow-up (clinical, laboratory, and computed tomography (CT) imaging) of a single-center, randomized, controlled CAD-Man trial comparing a CT-first strategy with a direct- invasive coronary angiography (ICA) diagnostic and management strategy, in 329 patients clinically referred for ICA with atypical angina or chest pain. Overall goal: The extension of CAD-Man follow-up (clinical, laboratory, and CT imaging) to approximately 10 years will provide the opportunity to compare plaque burden with CT-guided management versus direct-ICA at long-term and other endpoints.

NCT ID: NCT06214624 Enrolling by invitation - Clinical trials for Coronary Heart Disease

Exercise and Brain in Coronary Heart Disease

Heart-Brain
Start date: April 19, 2022
Phase: N/A
Study type: Interventional

The Heart-Brain project is a randomized controlled trial designed to examine the effects of two different exercise programs of 12-week duration: 1) aerobic high intensity interval training (HIIT), and 2) aerobic HIIT plus resistance training, on brain health and other outcomes in coronary heart disease patients.

NCT ID: NCT06194526 Enrolling by invitation - Coronary Stenosis Clinical Trials

Whole Blood Transcriptomic Signal According to Coronary Atherosclerotic Plaque Burden Assessed by CT Angiography

CORPLAQ-TRAIT
Start date: September 19, 2023
Phase:
Study type: Observational

The present clinical study aims to identify transcriptomic patterns derived from whole blood samples related to coronary atherotic burden. Additionally, as a secondary analysis, the research team will explore the algorithm's ability to detect the presence of aortic disease and pro-inflammatory cardiometabolic alterations, such as hepatic steatosis and surrogate markers of coronary inflammation.

NCT ID: NCT06154265 Enrolling by invitation - Clinical trials for Coronary Artery Disease

Intraoperative Echocardiography in Low-Risk CABG Surgery

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

This goal of this study is to better understand when and where intraoperative transesophageal echocardiography (TEE) should (or should not) be used during coronary artery bypass graft (CABG) surgeries.

NCT ID: NCT06083155 Enrolling by invitation - Clinical trials for Coronary Microvascular Dysfunction

The NetherLands Registry of Invasive Coronary Vasomotor Function Testing (NL-CFT)

NL-CFT
Start date: October 15, 2020
Phase:
Study type: Observational [Patient Registry]

The goal of this registry is to collect data on patients referred for clinically indicated coronary vasomotor function test (CFT) and answer different questions on prevalence, safety and outcomes. The registry is observational. Patients receive yearly online questionnaires on their anginal complaints for 5 years after their CFT.

NCT ID: NCT06031974 Enrolling by invitation - Clinical trials for Coronary Artery Disease

Dietary Intervention to Stop Coronary Atherosclerosis in Computed Tomography: Long-Term Follow-Up

DISCO-CT2
Start date: January 13, 2023
Phase:
Study type: Observational

A long-term evaluation of the impact of intensive diet and lifestyle intervention on coronary plaque dynamics in patients with coronary atherosclerosis diagnosed in computed tomography angiography (CCTA). 92 patients who completed the Dietary Intervention to Stop COronary Atherosclerosis in Computed Tomography study (DISCO-CT, NCT02571803) will be followed-up.

NCT ID: NCT06025305 Enrolling by invitation - Clinical trials for Coronary Artery Disease

Identifying Vulnerable CoronAry PLaqUes With Artificial IntElligence-assisted CT Angiography

VALUE
Start date: July 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to develop an automatic whole-process AI model to detect, quantify, and characterize plaques using coronary CT angiography in coronary artery disease patients. The main questions it aims to answer are: 1. Whether the AI model enables to detect and quantify coronary plaques compared with intravascular ultrasound or expert readers; 2. Whether the AI model enables to identify vulnerable plaques using intravascular ultrasound or optical coherence tomography as the reference standard. 3. Whether the AI model enables to predict future adverse cardiac events in a large cohort of 10,000 patients with non-obstructive CAD.

NCT ID: NCT05963620 Enrolling by invitation - Clinical trials for Coronary Artery Disease

Long-term Follow-up of a Randomized Comparison of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Surgery

Start date: January 1, 2023
Phase:
Study type: Observational

This is a long-term follow-up of a completed clinical trial which compared percutaneous coronary intervention (PCI) using sirolimus-eluting stents and coronary artery bypass grafting (CABG) in patients with unprotected left main coronary artery disease. The purpose of the study is to obtain retrospective long-term data on clinical outcome of the study population.

NCT ID: NCT05913999 Enrolling by invitation - Clinical trials for Coronary Artery Disease

Serial PET MPI in Patients Undergoing Cancer Treatment

Start date: June 1, 2023
Phase:
Study type: Observational

This study aims to evaluate the effects of cardiotoxic cancer therapies on myocardial blood flow (MBF) and perfusion in a prospective sample of VA patients.

NCT ID: NCT05820295 Enrolling by invitation - Stroke Clinical Trials

Improving How Older Adults at Risk for Cardiovascular Outcomes Are Selected for Care Coordination

Start date: May 17, 2023
Phase: N/A
Study type: Interventional

This pragmatic clinical trial embedded in an accountable care organization will determine the comparative effectiveness of two approaches for assigning care coordinators to older adults at risk for cardiovascular outcomes. The hypothesis is that assigning care coordinators to older adults based on perceived need will be more effective at preventing emergency department visits and hospitalizations compared to usual care.