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Coronary Artery Disease clinical trials

View clinical trials related to Coronary Artery Disease.

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NCT ID: NCT03312179 Completed - Clinical trials for Coronary Artery Disease

STEMI and Incretins

Start date: January 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

STEMI and multivessels coronary artery stenosis treatment, management and prognosis are by few literature data. Therefore we enrolled real world patients admitted for STEMI and associated to multi vessels coronary disease. these patients were divided in diabetics vs. non diabetics. Then these diabetics were divided in incretin users (6 months incerti treatment before study enrollment) vs. never incretin users. In these patients we studied all cause mortality, cardiac mortality, and major adverse cardiac events at 12 months follow up.

NCT ID: NCT03310801 Completed - Clinical trials for Coronary Artery Disease

LAAO With DAPT Versus Antithrombotic Therapy

Start date: August 1, 2016
Phase: N/A
Study type: Observational

This study will retrospectively review and compare clinical outcomes between left atrial appendage occlusion with dual antiplatelet therapy versus conventional antithrombotic therapy in patients with atrial fibrillation undergoing drug-eluting stent implantation.

NCT ID: NCT03308539 Recruiting - Clinical trials for Myocardial Infarction

Prediction of Coronary Artery Disease Severity by Epicardial Adipose Tissue Thickness

Start date: November 1, 2017
Phase: N/A
Study type: Observational

is to test the hypotheses that epicardial adipose tissue can be a marker of severity of coronary artery disease in myocardial infarction patients

NCT ID: NCT03307213 Not yet recruiting - Clinical trials for Coronary Artery Disease

BioFreedom QCA Study in CAD Patients

BioFreedomQCA
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

This study aims to demonstrate that the BioFreedom™ Cobalt Chromium Drug Coated Stent is non-inferior to the market authorized BioFreedom™ Stainless Steel Stent with respective to efficacy and shows a similar safety profile.

NCT ID: NCT03305926 Not yet recruiting - Clinical trials for Coronary Artery Disease

Connected Rehabilitation: an Alternative to Conventional Cardiovascular Rehabilitation?

eRCV
Start date: December 2017
Phase: N/A
Study type: Interventional

Cardiovascular rehabilitation (CVR) has major beneficial effects by improving physical capacity, accelerating return to activities and reinsertion and reducing mortality. It associates reconditioning to effort and therapeutic education for the optimal control of " risk factors ". It corresponds to a global approach to patients, thus counterbalancing the tendency to hyperspecialise in medicine. However, because of the lack of specialised centres, only a small proportion of patients (≈30%) are able to benefit. Numerical tools used in e-health, the deployment of the Internet and certain " connected " devices may provide alternatives outside hospital, by enabling the follow-up of patients and their physiological parameters (heart rate, blood pressure, weigh, physical activity…), and the adaptation - using an interactive web platform - of the physical activity programme, nutrition, compliance with medication and weaning from smoking. This project proposes to evaluate the effects of a so-called " connected " CVR programme, and to show its non-inferiority compared with a conventional CVR.

NCT ID: NCT03304496 Recruiting - Clinical trials for Coronary Artery Disease

Subcutaneous Nitroglycerin to Facilitate Trans-radial Access.

NITRAD-Sub
Start date: March 30, 2017
Phase: Phase 4
Study type: Interventional

Femoral artery approach to perform coronary procedures is considered the standard technique for vascular access due to optimal catheter control, lower thromboembolic complications and immediate access due to the large diameter of the artery. Trans-radial approach has been shown to reduce major bleeding complications, vascular complications related to the site of puncture, including death from all causes, and to prevent post-procedure limb rest, greater comfort for patients, immediate ambulation, early discharge and reduction of costs. Previous studies have shown that intravenous, topical and intraarterial use of nitroglycerin produces vasodilation of the radial artery. Extravascular (subcutaneous) administration of nitroglycerin is extremely effective in restoring the radial pulse, and allows adequate cannulation.

NCT ID: NCT03303781 Not yet recruiting - Clinical trials for Ischemic Heart Disease

BeSingCardioRehab: CR in Belgium Versus Singapore

Start date: November 1, 2017
Phase: N/A
Study type: Observational

Background: Cardiac rehabilitation is indicated for ischemic heart disease patients; the program content of which is well described in both European and American guidelines. In contrast, literature on cardiac rehabilitation program content and efficacy in the Asian population is sparse. Methods: BeSingCardioRehab will be an intercontinental, retrospective cohort study conducted in two cardiac rehabilitation referral centers in Belgium and Singapore. The first aim is to compare the impact of phase II center-based cardiac rehabilitation on Major Adverse Cardiac Events for ischemic heart disease patients between Europe (i.e. Belgian) and Asia (i.e. Singaporean) in the long-term. The second objective is to compare the efficacy of phase II cardiac rehabilitation on short-term morbidity (assessed with the validated SMART Risk Score) between index European and Asian ischemic heart disease patients. The level of compliance of the Belgian and Singaporean cardiac rehabilitation programs to European guidelines standards will also be evaluated. Hypotheses BeSingCardiorehab will be one of the first studies assessing cardiac rehabilitation in Asia. Based on the BeSingCardioRehab study results, phase II center-based cardiac rehabilitation programs, can/will be adapted in order to improve program content and outcomes.

NCT ID: NCT03301246 Not yet recruiting - Clinical trials for Coronary Artery Disease

Artimes Pro Low Profile Dilatation Catheters for Pre-Dilatation in Patients With Symptomatic Ischemic Heart Disease

Start date: November 20, 2017
Phase: N/A
Study type: Interventional

This is a prospective, non-randomized, open label, multi-center study including 60 patients with symptomatic ischemic heart disease with 70%-100% coronary artery stenoses and occlusions enrolled and treated in this investigational device study.

NCT ID: NCT03298659 Not yet recruiting - Clinical trials for Acute Myocardial Infarction

iFR Guided Multi-vessel Revascularization During Percutaneous Coronary Intervention for Acute Myocardial Infarction

iMODERN
Start date: November 1, 2017
Phase: N/A
Study type: Interventional

In patients with acute ST-elevation myocardial infarction (STEMI), 40-60% have multi-vessel disease with an increased cardiovascular morbidity and mortality. Although it is not recommended to revascularize noninfarct lesions during the acute intervention, recent investigations suggest the opposite and show improved outcome after direct revascularization of noninfarct lesions. It is undesirable to risk procedure-related complications by treating noninfarct lesions without impaired flow. It is currently unknown whether pressure guided revascularization of noninfarct lesions in the acute phase improves outcome compared to the current guidelines. The iMODERN trial aims to compare an iFR-guided intervention of noninfarct lesions during the acute intervention with a deferred stress perfusion CMR-guided strategy during the outpatient follow-up, to determine the optimal therapeutic approach for STEMI patients with multivessel lesions.

NCT ID: NCT03298282 Not yet recruiting - Clinical trials for Coronary Artery Disease

Integrated Coronary Imaging Registry

Start date: October 2017
Phase: N/A
Study type: Observational

The coronary images of selective angiography and optical coherence tomography with FFR(Fractional Flow Reserve) values of the intermediate lesions (50-70% stenosis) will be prospectively registered.