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Stroke clinical trials

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NCT ID: NCT05809596 Recruiting - Stroke Clinical Trials

HEAL-LAA Clinical Trial

HEAL-LAA
Start date: October 3, 2023
Phase: N/A
Study type: Interventional

The primary objective of this study is to collect real-world data on WATCHMAN FLX™ Pro Left Atrial Appendage Closure (LAAC) Device in patients with non-valvular atrial fibrillation.

NCT ID: NCT05809401 Recruiting - Stroke Clinical Trials

Pragmatic Assessment and Treatment for the Health System

PATHS
Start date: November 13, 2019
Phase: N/A
Study type: Interventional

The project goal is to promote a feasible and effective approach to communicative disorders in neurological and psychiatric populations, focused on the pragmatics of language. Pragmatics allows speakers to use and interpret language in context and to engage in successful communication. Pragmatic language disorder is widespread in clinical conditions and causes reduced social interactions and lower quality of life for both patients and their family. Yet it is seldom considered in assessment and rehabilitation.

NCT ID: NCT05809037 Recruiting - Stroke, Ischemic Clinical Trials

Evaluation of Noninvasive Vagus Nerve Stimulation on Functional Status in Ischemic Stroke

Start date: March 27, 2023
Phase: N/A
Study type: Interventional

In this study, the effectiveness of vagus nerve stimulation in patients with right and left hemiparesis will be compared with each other and with the sham application.

NCT ID: NCT05807269 Recruiting - Stroke Clinical Trials

Prevention and Rehabilitation of Stroke in Uganda

Start date: November 1, 2023
Phase:
Study type: Observational [Patient Registry]

Stroke is increasing in low-income countries in Africa, and knowledge is lacking on risk factors and how to prevent stroke as well as how to best use the resources for rehabilitation after stroke which are very limited. Knowledge generation within this area is therefore urgently needed. This collaboration between the research group HELD (Health and Everyday Life among people with neurological Disorders), Karolinska Institutet (KI) and the research surveillant site Africa Medical and Behavioral Sciences Organization (AMBSO) population health surveillance (PHS), will create substantial research opportunities to develop and improve prevention and rehabilitation for stroke, which is in line with the sustainable development goals to reduce the prevalence and mortality rates due to NCDs. AMBSO is collecting data from 17 000 households on many potential risk factors for stroke. Questions about stroke primary and secondary prevention of stroke and impact of stroke or need of rehabilitation could be added to the existing questionnaires such as the validated Ugandan version of the Stroke Impact Scale. This is intended to fulfill the aim of the network which is to increase the knowledge of occurrence and consequences of NCDs with a specific focus on stroke, which will be valuable for the development of preventive healthcare policy documents and guidelines for appropriate prevention strategies and rehabilitation interventions. Research questions in relation to NCDs with focus on stroke prevention and rehabilitation: - How many cases (prevalence) are reported in the targeted study sites and what is the mortality rate (incidence) that can specifically relate to stroke? - How does stroke and other NCDs affect and impact the quality of life for persons living in Uganda? - Which factors impact the recovery process after stroke? - What sort of rehabilitation is needed in the study areas for persons affected by stroke? In addition, risk factors of stroke such as diabetes and hypertension will be mapped.

NCT ID: NCT05807230 Completed - Stroke Clinical Trials

Three-level Network Rehabilitation Model

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The objective of this clinical trial was to compare the effects of different interventions on the recovery of stroke patients. The main question it aims to answer are: whether the intervention mode of integrated Chinese and western medicine is more valuable to implement. Researchers randomly assigned 90 patients to either group A or Group B, 45 in each group. Group A adopted the conventional three-level rehabilitation model; Group B adopted the three-level network rehabilitation model under the medical alliance for rehabilitation treatment with combination of Chinese and Western medicine. Fugl-Meyer motor score was used to assess the patient's motor ability, Berg balance scale was used to assess the patient's balance ability, National Institute of Health stroke scale was used to assess the patient's neurological function, and modified Barthel index was used to assess the patient's ability of daily living.

NCT ID: NCT05806658 Recruiting - Stroke Clinical Trials

A Theory-driven Visual Arts-based Intervention for Community-dwelling Stroke Survivors

Start date: September 18, 2023
Phase: N/A
Study type: Interventional

Stroke leads to psychosocial issues for community-dwelling stroke survivors in their recovery journey. Previous studies showed the benefits of visual arts-based interventions in enhancing self-efficacy and psychosocial functions. However, the interventions were not well designed with a theoretical framework. This study will evaluate the effectiveness of a theory-driven visual arts-based intervention on community-dwelling stroke survivors' psychosocial outcomes. A two-arm randomised controlled trial will be conducted to test the effects of this intervention and assess its feasibility in the community.

NCT ID: NCT05805748 Completed - Stroke Clinical Trials

Serious Game Therapy in Neglect Patients

Start date: September 6, 2017
Phase: N/A
Study type: Interventional

The growing field of new technologies offers new perspectives for neurorehabilitation. Serious games are a promising solution in the rehabilitation of cognitive impairments, and they may be useful in the rehabilitation of unilateral spatial neglect. Investigators developed a rehabilitation program for visual exploration training with a serious game and investigated its efficiency. Twelve patients with unilateral spatial neglect after a right hemispheric stroke were recruited. Six patients assigned to a group received both serious game training and conventional rehabilitation, and after only conventional rehabilitation; and six patients assigned to another group received first conventional rehabilitation and then serious game training and conventional rehabilitation. The investigators compared the two groups after rehabilitation.

NCT ID: NCT05805644 Not yet recruiting - Stroke, Acute Clinical Trials

Robot Mediated Therapy-Upper Limb Outcomes in Stroke

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

This study aims to determine the clinical outcomes of stroke patients who are provided with adjunctive robot-mediated task specific therapy(RMTT) and robot-mediated impairment training (RMIT) as compared to those who are provided with adjunctive RMIT.

NCT ID: NCT05804006 Recruiting - Stroke, Acute Clinical Trials

High-Intensity Interval Training in the Early Subacute Stroke With a Semi-recumbent Bike

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

Although High-intensity interval training (HIIT) exercise has emerged in recent years as a powerful time-efficient alternative to moderate-intensity continuous cardiovascular exercise training (MICT) to enhance neuroplasticity, motor, and cognitive functions, its feasibility remains to be determined early after stroke. Our study aims to investigate the feasibility of the HIIT program and its effects on functional abilities, cognitive function, and quality of life in early post-stroke.

NCT ID: NCT05801744 Recruiting - Stroke Clinical Trials

Operant Conditioning of Reflex Pathways to Improve Walking in Individuals Post-stroke

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the changes in reflex pathways in the paretic ankle plantarflexors in individuals with post-stroke hemiparesis using operant conditioning. We are recruiting 5 individuals with chronic post-stroke hemiparesis with foot drop in the affected leg to participate in the reflex training procedure. The study involves 40 visits with a total study duration of about 4 months.