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Stroke clinical trials

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NCT ID: NCT05801575 Recruiting - Stroke Clinical Trials

CHM Teabag Decrease Stroke Risk Among Hong Kong Elderly

Start date: February 2, 2023
Phase: N/A
Study type: Interventional

This stepped wedge cluster randomized controlled trial aims to examine the efficacy and safety of CHM teabag in decreasing stroke risk by machine-learning-based retinal image analysis in elderly population.

NCT ID: NCT05799326 Recruiting - Clinical trials for Acute Ischemic Stroke

Safety and Efficacy of Levofloxacin for Acute Ischemic Stroke

Start date: June 30, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of levofloxacin in treating acute ischemic stroke.

NCT ID: NCT05797792 Not yet recruiting - Stroke, Acute Clinical Trials

CHemical OptImization of Cerebral Embolectomy 2 (CHOICE 2).

CHOICE2
Start date: June 1, 2023
Phase: Phase 3
Study type: Interventional

Multi-center, randomized, parallel-group, superiority study to compare the efficacy of adjunct intra-arterial rt-PA versus not adjunct intra-arterial rt-PA in the improvement of the efficacy of mechanical thrombectomy in patients with large vessel occlusion acute ischemic stroke.

NCT ID: NCT05796843 Completed - Stroke Clinical Trials

360 Degrees Virtual Reality-based Mirror Therapy for Stroke Patients

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized controlled trial is to compare the effects of 360 degree virtual reality-based mirror therapy (360MT) to traditional mirror therapy (TMT) and conventional physical therapy (control group) on upper extremity function among stroke patients. The main questions it aims to answer are: - Would 360MT be more effective when treated for 4 weeks in outcome measure ments including: Fugl-Meyer Assessment for upper extremity (FMA-UE); manual function test (MFT); and box & block test (BBT)? - How would particants' experience be in terms of satisfactory and enjoyment during 360MT? The study will have three groups of participants who will be involved in different tasks: - 360MT group: will receive mirror therapy using a virtual reality device (HMD) and perform tasks with their paralyzed hand. Sessions will last 30 minutes, 3 times a week for 4 weeks. - TMT group: will receive mirror therapy using an acrylic mirror and perform finger, wrist, elbow exercises using their paralyzed limb. Sessions will last 30 minutes, 3 times a week for 4 weeks. - Control group: will receive conventional physical therapy consisting of exercises for the upper extremity, 60 minutes per day, 5 sessions a week, for 4 weeks.

NCT ID: NCT05795686 Recruiting - Stroke Clinical Trials

Evaluation of the Impact of the AVanCer Program Provided by the ARRPAC Day Center

Eval-ARRPAC
Start date: June 20, 2023
Phase: N/A
Study type: Interventional

In France, more than 150,000 strokes occur each year. Stroke is a major risk factor for dependency, representing the leading cause of acquired non-traumatic disability in adults. Head injuries, which are also very frequent, can leave similar neuropsychiatric sequelae. These events are brutal and their physical, psychological, emotional, social and financial consequences disrupt the lives of patients and their families. Thanks to improved access to thrombolysis and thrombectomy for the management of acute stroke, the prognosis has been profoundly improved. Nevertheless, the increase in post-stroke survival and the evolution of the type of after-effects require the development of support systems dedicated to these post-stroke patients. The same issues are raised for people who have suffered a head injury with similar consequences that require specialised care. Currently, health care is well structured for the acute phase and there is an improvement in the provision of care in specialised rehabilitation services, but the dedicated medico-social provision for people returning home remains insufficient despite the significant needs. The ARRPAC association (Accompaniment, Rehabilitation, Respite after Stroke and Cerebral Palsy) is setting up a new comprehensive medico-social support programme in Lyon (AVanCer programme, opening in June 2022) to improve the autonomy and adaptation capacities of patients and to relieve the social and psycho-affective burden of carers. This experimental day centre, which complements functional rehabilitation and recurrence prevention care, offers adults with brain injury sequelae and their carers therapeutic education programmes, adapted physical activity, social and cognitive remediation and therapeutic workshops, as well as a place for patients and their carers to exchange information and listen. To achieve its ambition, ARRPAC and the AVanCer programme must be integrated into the existing support offer, create partnerships with care structures and evaluate its added value to ensure its sustainability. In case of efficiency and demonstrated benefits for patients, carers and the health system, such a structure could be deployed in other territories. This study evaluates the implementation of the AVanCer programme in terms of its effect on the target audience, participants' experience and implementation according to the REAIM evaluative framework (Reach, Effectiveness, Adoption, Implementation, and Maintenance).

NCT ID: NCT05793827 Recruiting - Stroke Clinical Trials

Pilot Trial for Adults With Acquired Brain Injury

RCT
Start date: January 30, 2023
Phase: N/A
Study type: Interventional

This pilot study will compare a yoga program to a non-yoga exercise program in adults with brain injuries. The investigators will measure possible improvements in balance and heartrate. The investigators also plan to measure changes in brain function and link balance and/or heartrate improvements to changes in brain function. Ideally, this work will create a foundation for a larger-scale study.

NCT ID: NCT05793255 Completed - Stroke Clinical Trials

The Impact of Social Phone Calls on Adults Who Have Had a Stroke

Start date: March 23, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to see the impact of social visits, through weekly phone calls, on quality of life and health outcomes of depression, anxiety, loneliness, and self-rated health for adults who have experienced an ischemic or hemorrhagic stroke and to determine the benefit of these conversations on the student volunteer's perspective of adults who have survived a stroke

NCT ID: NCT05793177 Not yet recruiting - Stroke, Acute Clinical Trials

MONitoring Sedentary Behavior and Light Physical Activity in Patients With Stroke

MONSS
Start date: August 1, 2023
Phase: N/A
Study type: Interventional

This randomized control trial (RCT) aims to test the effect of a 12 weeks tailored behavioral intervention on stroke survivors living in the community and compare the results to a control group of stroke survivors participating in standard care. The intervention's purpose is to lower the time spend with sedentary behavior and raise the level of physical activity in stroke survivors throughout their everyday life. The intervention contains two motivational interviews with a focus on goal setting, action planning, motivation, fatigue management, and general information on life after stroke. The primary outcome for behavior change is objectively measured physical activity using an activity tracker (ActivPal4 Micro) and secondary glycohemoglobin and changes in quality of life.

NCT ID: NCT05792618 Completed - Stroke Clinical Trials

Stroke Patients and Family Longitudinal Study in Rural China

SaFaRI
Start date: September 1, 2022
Phase:
Study type: Observational

SaFaRI is a large prospective cohort study in Hebei Province, rural Northern China including 1,299 stroke patients and their spouses. Follow-up visits take place from baseline until the fifth year after the baseline survey, investigating the lifestyle and health behavior, disease history, medication and adherence to medication, health status and self-reported health, cognitive function, and medication cost. As additional measures, the investigators will collect information on hospitalization, recurrence, and vital status from county medical insurance system and death record system. Patients will also have a physical examination comprising of assessment of blood pressure, weight, height, waist circumference, neck circumference, grip strength and the "Timed Up and Go" test.

NCT ID: NCT05792605 Completed - Stroke Sequelae Clinical Trials

ATFL Evaluation With Ultrasound in Stroke Patients

ATFL
Start date: February 20, 2023
Phase:
Study type: Observational

ATFL thickness increases on the affected side of stroke patients and the homogeneous fibrillar structure is deteriorated.We aim to compare morphology of ATFL and Achilles tendon on the affected and unaffected sides using ultrasound in hemiplegic patients.