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Stroke clinical trials

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NCT ID: NCT02915484 Terminated - Stroke Clinical Trials

Transcranial Direct Current Stimulation (tDCS) in Chronic Post-Stroke Apathy

TDCS-PSA
Start date: June 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to test the efficacy and safety of tDCS (Transcranial Direct Current Stimulation) on apathy in stroke patients.

NCT ID: NCT02688413 Terminated - Stroke Clinical Trials

Study Evaluating the MindMotionPRO for Early Post-stroke Upper-limb Rehabilitation

MOVE-Rehab
Start date: August 2016
Phase: N/A
Study type: Interventional

Randomised controlled multi-centered study using MindMotionPRO, an immersive virtual reality based system for upper limb motor rehabilitation in early post-stroke patients. The study aims to evaluate the ability of MindMotionPRO technology to increase the rehabilitation dose. Effectiveness will be evaluated by validated rehabilitation performance scales. Cost-effectiveness will be assessed by the resource utilization.

NCT ID: NCT02680496 Terminated - Stroke Clinical Trials

Energy Consumption and Cardiorespiratory Load During Walking With and Without Robot-Assistance

Start date: February 2016
Phase: N/A
Study type: Interventional

The primary objective of the study is to investigate the energy consumption, cardiorespiratory load and perceived exertion, and how these parameters change, during walking with robot-assistance compared to walking on a treadmill and walking overground in stroke patients. A secondary objective is to investigate whether these changes or differences in energy consumption, cardiorespiratory load and perceived exertion during walking with and without robot-assistance in stroke patients are related to changes or differences spatiotemporal gait characteristics.

NCT ID: NCT02628847 Terminated - Stroke Clinical Trials

Sildenafil and Stroke Recovery

Start date: March 2012
Phase: Phase 1
Study type: Interventional

This is a small, pilot randomized clinical trial of administering sildenafil citrate to individuals within 10 days of ischemic stroke who have motor impairment and who are undergoing inpatient rehabilitation compared to placebo. The primary outcome is motor recovery at one and three months.

NCT ID: NCT02586415 Terminated - Cerebral Infarction Clinical Trials

Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3

DEFUSE 3
Start date: April 2016
Phase: N/A
Study type: Interventional

This is a study to evaluate the hypothesis that FDA cleared thrombectomy devices plus medical management leads to superior clinical outcomes in acute ischemic stroke patients at 90 days when compared to medical management alone in appropriately selected subjects with the Target mismatch profile and an MCA (M1 segment) or ICA occlusion who can be randomized and have endovascular treatment initiated between 6-16 hours after last seen well.

NCT ID: NCT02550509 Terminated - Stroke Clinical Trials

Changes in Echogenicity and Muscle Stiffness in Elastography After Botulinum Toxin Injection a Spastic Muscle

Start date: November 2013
Phase: N/A
Study type: Interventional

Muscle alterations and modifications passive biomechanical properties that occur on a spastic muscle contribute to functional disorders involved in spasticity. Botulinum toxin (TB) A is the reference treatment of the focused spasticity, and muscle source structural and biomechanical changes, very little studied in humans, especially since it is not one possibility of easily and reliably paraclinical assessment injections consequences.

NCT ID: NCT02544386 Terminated - Stroke Clinical Trials

Impact of Hemiplegia Due to Stroke on the Microarchitecture of the Bone

Start date: June 2009
Phase: N/A
Study type: Observational

In hemiplegic, there is very little data on the impact of neurological deficit on the microarchitecture independent of bone mineral density and composition of the bone marrow. Rare studies have shown the relationship between some micro-architectural parameters and severity of neurological deficit. There is no study in humans on the evolution of the parameters of the microarchitecture assessed by 3D micro-tomography in the early phase of the installation of neurological deficits after stroke, in terms of a bearing bone, tibia, that a non-load bearing bones, radius.

NCT ID: NCT02472288 Terminated - Urinary Retention Clinical Trials

Electroacupuncture on Post-stroke Urinary Retention

Start date: April 2015
Phase: N/A
Study type: Interventional

This study aimed to evaluate the effectiveness of adjuvant electroacupuncture therapy for the post-stroke patients with urinary retention under conventional treatments, compared with sham electroacupuncture.

NCT ID: NCT02461355 Terminated - Stroke Clinical Trials

Transcranial Direct Current Stimulation for Post-Stroke Aphasia

Start date: June 2015
Phase: N/A
Study type: Interventional

This is a randomized, crossover design trial that will compare how anodal transcranial direct current stimulation (tDCS) versus sham tDCS administered during multiple sessions of scripting therapy affects the acquisition and retention of trained scripts.

NCT ID: NCT02422940 Terminated - Clinical trials for Post-ischemic Stroke

An Extension Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine Extended-Release Tablets for the Treatment of Chronic Post-Ischemic Stroke Walking Deficits in Subjects Who Participated in the DALF-PS-1016 Study

MILESTONE?
Start date: April 2015
Phase: Phase 3
Study type: Interventional

This is an extension study to evaluate the long-term safety, tolerability, and efficacy of two dose strengths of dalfampridine-ER twice daily tablets when administered for at least 12 months to subjects with chronic post-ischemic stroke walking deficits who have completed the controlled, double-blind Study DALF-PS-1016.