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Stroke clinical trials

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NCT ID: NCT02628847 Terminated - Stroke Clinical Trials

Sildenafil and Stroke Recovery

Start date: March 2012
Phase: Phase 1
Study type: Interventional

This is a small, pilot randomized clinical trial of administering sildenafil citrate to individuals within 10 days of ischemic stroke who have motor impairment and who are undergoing inpatient rehabilitation compared to placebo. The primary outcome is motor recovery at one and three months.

NCT ID: NCT02586415 Terminated - Cerebral Infarction Clinical Trials

Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3

DEFUSE 3
Start date: April 2016
Phase: N/A
Study type: Interventional

This is a study to evaluate the hypothesis that FDA cleared thrombectomy devices plus medical management leads to superior clinical outcomes in acute ischemic stroke patients at 90 days when compared to medical management alone in appropriately selected subjects with the Target mismatch profile and an MCA (M1 segment) or ICA occlusion who can be randomized and have endovascular treatment initiated between 6-16 hours after last seen well.

NCT ID: NCT02550509 Terminated - Stroke Clinical Trials

Changes in Echogenicity and Muscle Stiffness in Elastography After Botulinum Toxin Injection a Spastic Muscle

Start date: November 2013
Phase: N/A
Study type: Interventional

Muscle alterations and modifications passive biomechanical properties that occur on a spastic muscle contribute to functional disorders involved in spasticity. Botulinum toxin (TB) A is the reference treatment of the focused spasticity, and muscle source structural and biomechanical changes, very little studied in humans, especially since it is not one possibility of easily and reliably paraclinical assessment injections consequences.

NCT ID: NCT02544386 Terminated - Stroke Clinical Trials

Impact of Hemiplegia Due to Stroke on the Microarchitecture of the Bone

Start date: June 2009
Phase: N/A
Study type: Observational

In hemiplegic, there is very little data on the impact of neurological deficit on the microarchitecture independent of bone mineral density and composition of the bone marrow. Rare studies have shown the relationship between some micro-architectural parameters and severity of neurological deficit. There is no study in humans on the evolution of the parameters of the microarchitecture assessed by 3D micro-tomography in the early phase of the installation of neurological deficits after stroke, in terms of a bearing bone, tibia, that a non-load bearing bones, radius.

NCT ID: NCT02472288 Terminated - Urinary Retention Clinical Trials

Electroacupuncture on Post-stroke Urinary Retention

Start date: April 2015
Phase: N/A
Study type: Interventional

This study aimed to evaluate the effectiveness of adjuvant electroacupuncture therapy for the post-stroke patients with urinary retention under conventional treatments, compared with sham electroacupuncture.

NCT ID: NCT02461355 Terminated - Stroke Clinical Trials

Transcranial Direct Current Stimulation for Post-Stroke Aphasia

Start date: June 2015
Phase: N/A
Study type: Interventional

This is a randomized, crossover design trial that will compare how anodal transcranial direct current stimulation (tDCS) versus sham tDCS administered during multiple sessions of scripting therapy affects the acquisition and retention of trained scripts.

NCT ID: NCT02422940 Terminated - Clinical trials for Post-ischemic Stroke

An Extension Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine Extended-Release Tablets for the Treatment of Chronic Post-Ischemic Stroke Walking Deficits in Subjects Who Participated in the DALF-PS-1016 Study

MILESTONE?
Start date: April 2015
Phase: Phase 3
Study type: Interventional

This is an extension study to evaluate the long-term safety, tolerability, and efficacy of two dose strengths of dalfampridine-ER twice daily tablets when administered for at least 12 months to subjects with chronic post-ischemic stroke walking deficits who have completed the controlled, double-blind Study DALF-PS-1016.

NCT ID: NCT02416791 Terminated - Stroke Clinical Trials

Robotic Therapy and Transcranial Direct Current Stimulation in Patients With Stroke

ROTS
Start date: June 2015
Phase: N/A
Study type: Interventional

Stroke is the second cause of death worldwide and represented the first cause of death in Brazil between 2006 and 2010. Most patients survive, and there is a need to develop cost-effective rehabilitation strategies to decrease the burden of disability from stroke. This study addresses this important issue, by combining two different interventions in the early phase post-stroke: robotic therapy associated or not with transcranial direct current stimulation (tDCS), as adjuvant interventions to conventional physical therapy, for motor upper limb rehabilitation.

NCT ID: NCT02362984 Terminated - Clinical trials for Acute Ischemic Stroke

DLBS1033 for the Treatment of Acute Ischemic Stroke

Start date: October 2014
Phase: Phase 3
Study type: Interventional

This is a prospective, randomized, double-blind, and controlled clinical study to investigate the effects of DLBS1033 in conjunction with standard therapy compared to standard therapy alone in acute ischemic stroke patients.

NCT ID: NCT02317055 Terminated - Stroke Clinical Trials

Magnetic Resonance Imaging Evaluation of the Tissular Oxygen Saturation in Brain

GADOXY
Start date: June 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to measure the tissular oxygen saturation in brain by magnetic resonance imaging on subjects and to correlate the results with near infrared spectroscopy measurements.