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Stroke clinical trials

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NCT ID: NCT03502408 Recruiting - Clinical trials for Stroke, Acute Cerebral Infarction

Perfusion Imaging Evaluation for Ischemic Stroke on 6-24 Hours Undergoing Endovascular Thrombectomy

PESET
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

This study aims to evaluate the hypothesis that thrombectomy devices plus medical management leads to superior clinical outcomes in acute ischemic stroke patients at 90 days as compared to medical management alone in appropriately selected subjects with the Target Mismatch Profile and an MCA (M1 and M2 segment) or ICA occlusion or BA who have endovascular thrombectomy initiated between 6-24 hours after last seen well.

NCT ID: NCT03501797 Recruiting - Stroke Clinical Trials

Choir Singing in Aphasia Rehabilitation

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

This study evaluates the verbal, cognitive, emotional, and neural efficacy of a choir singing intervention in chronic aphasic patients and their caregivers. Using a cross-over RCT design, half of the participants receive a 4-month singing intervention during the first half of the study and half of the participants during the second half of the study.

NCT ID: NCT03501186 Recruiting - Chronic Stroke Clinical Trials

Effects of Backward Gait on Sand on Improving the Gait Parameters of Patients With Chronic Stroke.

Start date: January 12, 2017
Phase: N/A
Study type: Interventional

Gait training in stroke is a complex process of motor learning although restoring patients ability to walk would not prepare the individual with the challenges faced in the real environment. The aim is not simply walking in controlled environment, but to achieve dynamic walking. Dynamic walking is the ability of an individual to adjust to the changing surfaces and terrains. thereby returning to achieve active participation in the community. Hence, recovery of walking ability is the primary goal when planning treatment for patients with stroke.

NCT ID: NCT03499574 Recruiting - Stroke, Acute Clinical Trials

Feasibility Study of Biofeedback in Dysphagia Therapy Post Stroke

Start date: January 26, 2018
Phase: N/A
Study type: Interventional

This study will investigate the feasibility of delivering swallowing therapy using surface electromyography as a means of biofeedback to patients with dysphagia in the acute stroke setting. It will investigate trends in efficacy by comparing biofeedback therapy to usual care. The results will inform future dosing and efficacy studies.

NCT ID: NCT03499210 Recruiting - Stroke Clinical Trials

Safety Evaluation of the ReWalk Restore Device in Subjects With Mobility Impairments Due to Stroke

Start date: March 29, 2018
Phase: N/A
Study type: Interventional

A multi-site, interventional, non-comparative, single-arm trial to evaluate the safety of the ReWalk Restore device in subjects with mobility impairments due to ischemic or hemorrhagic stroke.

NCT ID: NCT03492229 Recruiting - Stroke Clinical Trials

Cortical Priming to Optimize Gait Rehabilitation Post Stroke

Start date: January 1, 2014
Phase: N/A
Study type: Interventional

Over four million stroke survivors currently living in the United States are unable to walk independently in the community. To increase the effectiveness of gait rehabilitation, it is critical to develop therapies that are based on an understanding of brain adaptations that occur after stroke. This project will be the first step towards the development of a novel therapeutic approach using brain stimulation to increase walking capacity in stroke survivors and understand the neural mechanisms that are associated with impairment and functional recovery.

NCT ID: NCT03490552 Recruiting - Thrombosis Clinical Trials

RNA Sequencing Analysis in Large Vessel Occlusion Stroke DATA Bank

RNASA-LVOSB
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Introduction: the source of embolic stroke , in thrombotic embolism , is of unknown origin in 30-40% of cases. Fortunately , Mechanical thrombectomy provide a direct method to retrieve the stroke-incriminated clots from stroke patients for possibility of exo-autopsy analysis.

NCT ID: NCT03485820 Recruiting - Ischemic Stroke Clinical Trials

A Novel Transition Program to Reduce Disability After Stroke

COMPASS
Start date: January 18, 2018
Phase: N/A
Study type: Interventional

This study evaluates a program designed to help individuals transition home from inpatient rehabilitation following and ischemic stroke. Half of the participants will receive a stroke education program while the other half will receive an environmental modifications program.

NCT ID: NCT03485040 Recruiting - Stroke, Ischemic Clinical Trials

Stroke Motor Rehabilitation and Recovery Study

SMaHRT
Start date: June 9, 2017
Phase:
Study type: Observational

SMaHRT (Stroke Motor reHabilitation and Recovery sTudy) is a longitudinal study aimed at understanding the natural history of upper extremity motor recovery after ischemic stroke.

NCT ID: NCT03484351 Recruiting - Stroke Clinical Trials

The Fall Monty Activity Programme Feasibility Study

FallMAP
Start date: April 2018
Phase: N/A
Study type: Interventional

Between 45-73% of people who have had a stroke fall over in the months and years following their stroke. Falls not only lead to injuries such as broken hips, but they may also lead to fear of falling. As a consequence people can get fearful to walk, keep up their household tasks and their social activities such as visiting friends and family. Research has shown that exercises for strength and balance can help both older people and patients after stroke to get fitter and healthier and help to prevent them from having a fall. People also have less falls if they have learned about falls facts and home safety precautions. Research has further suggested that people have less fear of falling and less injuries from a fall if they have learned how to fall ('safe landing' strategies). Based on these research findings the researchers have developed a new falls prevention programme called the Fall Monty Activity Programme (FallMAP). This programme aims to aid in functional recovery and reduce falls by combining a mix of activities such as falls education, strength and balance exercises, and activities that teach people how to get up from the floor and how to fall safely. Especially because people with residual impairments following a stroke have an increased risk of a fall, the feasibility of this programme will be tested in a small group of people after stroke first. This study is a first step in establishing whether the different components of the FallMAP are acceptable and practical for both patients after stroke and staff who deliver the program. In particular, it is important to evaluate if it is feasible to provide the seven combined components as one comprehensive programme. Secondly, the question whether participating in the programme can positively influence the participants' fear of falling, quality of life, leg strength, balance and mobility will be explored. If this feasibility study suggests the programme can work in the clinical setting, then a definitive randomised controlled trial will be proposed in order to look at whether the full programme is effective at reducing falls in patients after stroke.