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Stroke clinical trials

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NCT ID: NCT03246256 Recruiting - Stroke Clinical Trials

Information Recall on Informed Consent to Intravenous Thrombolysis in Patients With Acute Ischaemic Stroke.

Start date: December 21, 2016
Phase: N/A
Study type: Observational

The aim of the study is to investigate the ability to recall information given during informed consent on intravenous thrombolysis in patients with acute ischaemic stroke.

NCT ID: NCT03246217 Recruiting - Stroke Clinical Trials

Therapeutic Instrumental Music Performance With Sensory-Enhanced Motor Imagery in Chronic Post-Stroke Rehabilitation

Start date: July 20, 2017
Phase: N/A
Study type: Interventional

Research has shown that music engages the brain bilaterally throughout cortical and subcortical regions, accessing extended sensorimotor, cognitive and affective networks. This research explores the hypothesis that use of these shared neural networks allows neurologic music therapy interventions targeting upper extremity motor control to promote plasticity and functional improvements in persons recovering from a cerebrovascular accident. The potential therapeutic benefits of these interventions on attentional processes and affective responding will also be examined.

NCT ID: NCT03246139 Recruiting - Stroke Clinical Trials

Action Observation, Imagery and Execution for Stroke Rehabilitation

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

The specific study aims will be: 1. To investigate the short- and long-term treatment effects of action observation, imagery, and execution therapy (AOIE) compared with an action observation therapy (AO) group and a customary rehabilitation group as controls on different aspects of outcomes in patients with stroke. 2. To examine the neural mechanisms and changes in cortical neural activity after the interventions in stroke patients. 3. To examine the correlations between AOIE-induced brain activation changes and the clinical efficacy of AOIE. 4. To identify who are the possible good responders to the therapy based on baseline motor function and motor imagery ability of the participants.

NCT ID: NCT03244215 Recruiting - Clinical trials for Transient Ischemic Attack

The Recurrence Study

Start date: February 17, 2016
Phase: N/A
Study type: Interventional

The primarily goal of the research is to better understand progression of disease in patients who present with an acute stroke to the Hamad General Hospital (HGH) stroke and Transient Ischemic Attack (TIA) clinic. The investigators are specifically interested in patients who have diabetes and have a stroke. The patients enrolled into the research will have detailed clinical evaluation and their imaging studies (MRI and Doppler) will be reviewed. After informed consent, subjects will be examined in the stroke Ward /TIA clinic upon recruitment, and later at less than 48 hours of recruitment (blood extraction and urine samples) and for follow up visits at 1 month+/-7 days (clinical evaluation and to extract blood and urine samples), at 3 months (telephonic conversation only) and at 1 year (clinical and repeat MRI brain). During the initial visit at the ward the investigators will collect serum and plasma for proteomic and metabolomic studies. These will be repeated at less than 48 hours and at 1 month+/-7 days. Investigators will test the effects of risk factors such as diabetes/stroke on the endothelial procoagulant and inflammatory state at onset and evaluate if best medical control leads to improvement in such markers.The repeated studies will determine if better management and presence of certain blood biomarkers can predict or translate to slower progression of disease and correlate it with clinical status.

NCT ID: NCT03231384 Recruiting - Ischemic Stroke Clinical Trials

Rt-PA Thrombolytic Therapy in Combination With Remote Ischemic Conditioning for Acute Ischemic Stroke

Start date: July 30, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the safety and feasibility of remote limb ischemic conditioning(RIC) in acute ischemic stroke patients who received r-tPA thrombolytic therapy.

NCT ID: NCT03231293 Recruiting - Hypertension Clinical Trials

Fimasartan Blood Pressure Lowering After Acute Stroke

FABULOUS
Start date: July 28, 2016
Phase: N/A
Study type: Observational

This study evaluates the effectiveness of fimasartan-based antihypertensive treatment and prognosis in post-acute phase of ischemic stroke or transient ischemic attack patients. All participants will receive fimasartan, and the investigators will follow them up for 6 months.

NCT ID: NCT03230695 Recruiting - Stroke Clinical Trials

Robotic Therapy and Brain Stimulation in the Early Phase After Stroke

Start date: July 2017
Phase: N/A
Study type: Interventional

Stroke is the second cause of death worldwide and the majority of the survivors remain with motor impairments. Inhibition of the motor cortex of the unaffected hemisphere has emerged as a potential intervention to enhance effects of other rehabilitation strategies on improvement of motor performance of the paretic upper limb. In this proof-of-concept study we will evaluate the effects of inhibition of the motor cortex of the unaffected hemisphere associated with robotic therapy on improvement of motor performance of the paretic upper limb in the early phase post-stroke.

NCT ID: NCT03229902 Recruiting - Stroke Sequelae Clinical Trials

Mantra Meditation in Subjects That Have Chronically Impaired Attention After Stroke

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

There is an evidence gap on whether meditation may improve behaviorally measured attention after stroke, but preliminary research is promising. This study is the first-ever investigation of whether mantra meditation may improve chronic, severe impairment in attention after stroke.

NCT ID: NCT03223571 Recruiting - Stroke Clinical Trials

Brain Plasticity Mapping Post-stroke

MAPPY
Start date: July 30, 2017
Phase: N/A
Study type: Observational

The investigators believe that the initial cerebral connectivity as well as its evolution immediate post-stroke could be correlated to the amount of motor recovery. Therefore a cohort of 21 people early post-stroke, and 6 weeks post standard routine rehabilitation will be analyzed. Clinical, kinematic and imaging (MRI) data will be compared with 12 healthy controls. Kinematic movement information has been collected within the fMRI. By integrating multi-modal clinical, kinematic and MRI, the study aims to identify biomarkers of recovery to improve patient specific evaluation post-stroke in order to adapt rehabilitation protocols accordingly and to improve functional gain.

NCT ID: NCT03219346 Recruiting - Stroke Clinical Trials

The Effectiveness of Oral Health in Improving Dysphagia of Patients After Stroke of Swallowing Function and Oral Health Quality of Life

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

The prevalence of chewing dysphagia in the domestic rehabilitation department ward was about 53.61%.Nasal tube retention of about 31%, due to nasogastric tube feeding, often overlooked oral hygiene, easy to cause respiratory tract infection. At the same time, oral hygiene will also affect the effectiveness of swallowing treatment, is worthy of attention to health problems.