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Stroke clinical trials

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NCT ID: NCT05812846 Completed - Stroke Clinical Trials

Monitoring of the Ischemic Stroke Patient Through the Use of New Serum Biomarkers and MRI Imaging

Start date: December 4, 2018
Phase:
Study type: Observational

Aim of this study will be the evaluation (by ELISA quantification and quantitative RT-PCR) of circulating biomarkers of damage and regeneration in patients affected by ischemic stroke. The biomarker levels will be measured from the acute event (48h) and in subsequent 4 times (7 days, 30 days, 90 days, 180 days) following hospitalization, up to 6 months after the acute event. These data will then be correlated for all five times with the clinical scales normally used for patient evaluation and will also be associated with MRI-DTI measurements performed in the post-acute (30 days) and post-discharge (180 days) phase.

NCT ID: NCT05812794 Completed - Childhood Stroke Clinical Trials

TOlerability of Transcranial Direct Current Stimulation in Pediatric Stroke Survivors

TOPSS
Start date: June 30, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the tolerability of tDCS in childhood stroke survivors and to assess for improvement in arm function in patients receiving tDCS and occupational therapy

NCT ID: NCT05812638 Recruiting - Stroke Clinical Trials

Mental Imagery for Lower Limb Functions

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

Stroke is a neurological impairment occurs due to cardiovascular abnormality and cerebrovascular disease. The term 'stroke' is mostly used when there is sudden loss of function of the body due any abrupt changes.The rates of disability are increasing along with mortality and morbidity rates due to stroke. The poor motor performance of lower limb affects gait severely. The slow velocity and other gait deviations limit the stroke survivors' ability to perform ADL's and interfere with their quality of life. Hence, rehabilitation is obligatory for these patients to improve their quality of life

NCT ID: NCT05811819 Recruiting - Stroke Clinical Trials

Hand Training & Brain Changes

Start date: October 19, 2022
Phase: N/A
Study type: Interventional

10 participants with upper-limb impairment will be recruited from community sources. They will be invited to participate in a 15-day trial involving the IRegained device. The study will involve 2 assessment visits to McMaster, before and after the treatment, and 15 treatment visits. The data from the pilot study will be analyzed both quantitatively and qualitatively, as outcomes and explicit feedback from participants will be used to further optimize the device for future studies.

NCT ID: NCT05811806 Completed - Stroke Clinical Trials

Physiological Changes From Hand Movement Training

Start date: May 2, 2022
Phase: N/A
Study type: Interventional

11 participants with upper-limb impairment will be recruited from community sources. They will be invited to participate in a 15-day trial involving the IRegained device. The study will involve 2 assessment visits to Baycrest, before and after the treatment, and 15 treatment visits. The data from the pilot study will be analyzed both quantitatively and qualitatively, as outcomes and explicit feedback from participants will be used to further optimize the device for future studies.

NCT ID: NCT05811494 Recruiting - Stroke Clinical Trials

Effectiveness of Multiple Robotic Gait-Devices for Improving Walking Ability in Subacute Stroke Patients

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to know the effectiveness of different robotic devices for gait rehabilitation in stroke patients

NCT ID: NCT05810857 Not yet recruiting - Stroke Clinical Trials

Comparative Effects of Motor Relearning Programme Versus Mirror Therapy on Balance and Gait in Chronic Stroke Patients

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

To determine the effect of Motor Relearning Program versus Mirror Therapy for balance and gait in chronic ischemic stroke patients

NCT ID: NCT05810844 Not yet recruiting - Stroke Clinical Trials

Comparison Of Effects of MRP Vs NDT For Balance and Gait in Chronic Ischemic Stroke Patients RCT

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

To determine the comparison between effects of Motor Relearning Program (MRP) and Neuro-Development Treatment (NDT) on balance and gait in chronic ischemic stroke patients.

NCT ID: NCT05809973 Recruiting - Stroke, Acute Clinical Trials

The Oslo Study of Visual Impairment After Stroke (StrokeVIS)

StrokeVIS
Start date: November 15, 2021
Phase:
Study type: Observational

Longitudinal, prospective, single-center observational study of visual impairment after stroke. Population: Patients admitted with acute ischemic stroke at the Regional Stroke Unit at Oslo University Hospital who are assessed to not have more serious neurological deficits than to be eligible for a prospective observational study of visual impairment. National Institute of Health Stroke Scale (NIHSS) will be used for screening of the patients eligible for the study with cut off of NIHSS 20. Based on the number of patients admitted to our center to include 120 patients in the StrokeVIS study. The study aims are: 1. To determine the prevalence of visual impairment in stroke patients in the acute phase and after 3 months. 2. To compare visual impairment in those treated with EVT and those not. 3. To determine the sensitivity and specificity of the Vision Screening Assessment (VISA) tool for detection of visual impairment in stroke patients. 4. To assess possible association between brain MRI lesions and visual impairment in stroke patients in the acute phase. 6) To assess any cognitive deficits at 3-month follow-up that could impact visual function. Inclusion criteria: 1. Acute ischemic stroke and NIHSS < 20 2. Age ≥18 years. 3. Written informed consent of the patient or oral informed consent witnessed by a doctor. Exclusion criteria: 1. NIHSS < 20 2. No willingness and ability of the patient to participate in all baseline and follow-up examinations. Duration of study participation: 3 months.

NCT ID: NCT05809921 Completed - Clinical trials for Acute Ischemic Stroke Due to Medium-vessel-occlusion

Dual IntraVenous Thrombolysis Approach (DIVA) in Patients With Medium-vessel-occlusion Strokes: a Retrospective Study

DIVArétro
Start date: May 17, 2023
Phase:
Study type: Observational

The purpose of this study (Dual IV thrombolysis Approach (DIVA) study) is to assess a new medical strategy for Medium-vessel-occlusion (MeVO) strokes, based on a second IV thrombolysis with tenecteplase (TNK) for persistent intracranial occlusion on MRI 1-2 hours after standard alteplase infusion. The DIVA-study results were compared with a similar cohort of MeVO strokes patients treated with standard therapy (single IVT with alteplase) during the same timeframe in another stroke unit.