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Hypertension clinical trials

View clinical trials related to Hypertension.

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NCT ID: NCT05937685 Recruiting - Stroke Clinical Trials

Reducing Blood Pressure in Patients With High Cardiovascular Risk in the Safety-Net

BP-REACH
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

BP-REACH is a study of a team-based (pharmacist and health coach) program for lowering blood pressure for people with a prior stroke or heart attack in the Los Angeles Department of Health Services public healthcare system. The goal of this clinical trial is to test if this team based program is better at helping people reduce their blood pressure than usual care for people with prior heart attack or stroke. The main questions it aims to answer are: - Do people in the REACH BP program have lower blood pressure at 12 months compared to those getting usual care? - Do people in the REACH BP program have better Life's Essential 8 scores and patient experience compared to those getting usual care?

NCT ID: NCT05935865 Recruiting - Clinical trials for Pulmonary Hypertension

Monitoring of the Influence of Approved PH-therapies RV-PA Coupling

Start date: February 13, 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about the acute (days) changes in right ventricular functions caused by initiation of pharmacological therapies in patients with precapillary pulmonary hypertension. The main question it aims to answer is: • Course of afterload and intrinsic contractility throughout the hospital stay Participants will be equipped with a device for continuous monitoring and recording of the right ventricular pressure signal.

NCT ID: NCT05935605 Recruiting - Clinical trials for Pulmonary Hypertension

Pulmonary Hypertension in Left Heart Disease

Start date: July 20, 2023
Phase:
Study type: Observational

The goal is to compare patients with and without varying severity of pulmonary vascular disease based upon hemodynamic signatures, echocardiographic measures, and lung ultrasound, in tandem with expired gas metabolic testing and blood sampling.

NCT ID: NCT05934526 Recruiting - Clinical trials for Pulmonary Arterial Hypertension

Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)

Start date: December 28, 2023
Phase: Phase 3
Study type: Interventional

The primary objective of the study is to determine the effect of seralutinib on improving exercise capacity in subjects with WHO Group 1 PAH who are FC II or III. The secondary objective for this trial is to determine time to clinical worsening.

NCT ID: NCT05934383 Not yet recruiting - Hypertension Clinical Trials

Safety and Efficacy of Ultrasound Renal Denervation in Kidney Transplantation Patients With Uncontrolled Hypertension

RESTART
Start date: September 2023
Phase: N/A
Study type: Interventional

This prospective, single-arm, interventional study is designed to assess the short-term and long-term safety and efficacy of bilateral ultrasound renal sympathetic denervation (RDN) of the native kidneys in renal transplant patients with uncontrolled hypertension. Objectives: - To assess the short-term and long-term changes in ambulatory and office blood pressure (BP) following native kidney RDN in renal transplant patients - To assess the long-term safety of native kidney RDN in renal transplant patients - To assess the short-term and long-term change in antihypertensive drug prescriptions following native kidney RDN in renal transplant patients - To assess the short-term and long-term change in adherence to antihypertensive drugs following native kidney RDN in renal transplant patients

NCT ID: NCT05931224 Completed - Clinical trials for Essential Hypertension

Clinical Trial to Evaluate the Efficacy and Safety of D064 and D702 Combination Therapy

Start date: June 28, 2023
Phase: Phase 3
Study type: Interventional

Clinical Trial to Evaluate the Efficacy and Safety of D064 and D702 Combination Therapy

NCT ID: NCT05931003 Recruiting - Hypertension Clinical Trials

Reconstruction of the Carotid Bifurcation in Patients With Arterial Hypertension of 2-3 Degrees

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Carotid endarterectomy (CEA) is a well-established procedure for preventing ischemic brain damage. Stenosis of the precerebral vessels are often combined with arterial hypertension. In recent decades, many works have appeared that indicate that the course of arterial hypertension (AH) changes after CEA. However, it remains unknown how this is related to the choice of surgical tactics.

NCT ID: NCT05930028 Recruiting - Clinical trials for Essential Hypertension

A Study to Evaluate the Efficacy and Safety of BR1017A and BR1017B Combination Therapy in Essential Hypertension Patients With Primary Hypercholesterolemia

Start date: July 13, 2023
Phase: Phase 3
Study type: Interventional

The objective of this clinical study is to evaluate the efficacy and safety by comparing BR1017A+BR1017B treatment group to BR1017A treatment group and BR1017B treatment group respectively at Week 8 in essential hypertension patients with primary hypercholesterolemia

NCT ID: NCT05929170 Active, not recruiting - Hypertension Clinical Trials

Comparison of Extremely Obese Patients Undergoing Gastric Sleeve Surgery

Start date: April 1, 2021
Phase:
Study type: Observational

By the comparison of the preoperative and postoperative data of approximately 160 patients undergoing gastric sleeve surgery, we try to draw conclusions about the effectiveness of gastric sleeve surgery, expected complication rate.

NCT ID: NCT05928702 Recruiting - Clinical trials for Arterial Hypertension

Temperature-elevating Armbaths for Arterial Hypertension

Start date: June 23, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized controlled trial is to learn about the effect of a hydrotherapeutic approach - a temperature-elevating armbath - in people with arterial hypertention. The main question[s] it aims to answer are: - Can this kind of hydrotherapy lower the blood pressure and therefore be an additional approach to medical treatment in arterial hypertension? - Besides blood pressure regulation, does this intervention affect sleep quality when being performed at night time or does it affect overall quality of life? Participants will be advised to perform a temperature-elevating armbath once a day for 30 minutes on at least 5 days per week over 8 weeks. The comparison group will continue treatment as usual, like continue their medication. 24h blood pressure measurements will be performed at the beginning, after 8 weeks and after 6 months in both groups. The main goal is to evaluate whether the intervention group shows lower blood pressure levels after a certain time of treatment. After 6 months (end of trial) the control group will be offered to learn the temperature elevating armbath as well.