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Hypertension clinical trials

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NCT ID: NCT03794583 Enrolling by invitation - Clinical trials for Chronic Obstructive Pulmonary Disease

Inhaled Treprostinil in Patients With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)

PERFECTOLE
Start date: December 21, 2018
Phase: Phase 3
Study type: Interventional

This open-label study will evaluate the safety of continued therapy with inhaled treprostinil in subjects who have completed Study RIN-PH-304. This study hypothesizes that long-term safety findings will be similar to those observed in the randomized, placebo-controlled, double-blind, adaptive study 'A Phase 3, Randomized, Placebo-controlled, Double-blind, Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Patients with Pulmonary Hypertension due to Chronic Obstructive Pulmonary Disease (PH-COPD)(RIN-PH-304).

NCT ID: NCT03794531 Enrolling by invitation - Obesity Clinical Trials

Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico

PROSPECT
Start date: December 17, 2018
Phase:
Study type: Observational

The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing cardiovascular-related disparities in Puerto Rico. To this end, investigators will establish 'PROSPECT: Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic disease Trends', an island-wide, longitudinal population cohort of 2,000 adults (30-75 years) in PR recruited with a multi-frame sampling of probabilistic plus community approaches, and assessed in a network of several partner clinics across the island. The study will collect comprehensive data on multiple psychosocial, dietary, and food-related factors, CVD biological markers, and medical record data, with follow-up at 2-years, and will assess variations by urban-rural area and by timing before-after Maria.

NCT ID: NCT03783650 Enrolling by invitation - Clinical trials for Pediatric Hypertension

Boosting Primary Care Awareness and Treatment of Childhood Hypertension

BP-CATCH
Start date: September 1, 2018
Phase: N/A
Study type: Interventional

The proposed research, building on an ongoing AHRQ-funded research project to prevent pediatric diagnostic errors in primary care (R01HS023608) and using a prospective, cluster-randomized, stepped wedge design, will investigate whether 1) a quality improvement collaborative (QIC) intervention without subspecialist involvement, 2) a QIC with subspecialists and primary care physicians (PCPs) mutually engaged, and/or 3) a hub and spoke co-diagnosis, co-management model where PCPs diagnose and manage pediatric hypertension (HTN) with a supporting subspecialist advisor, reduce errors in pediatric HTN diagnosis and management compared to each other and usual care.

NCT ID: NCT03762577 Enrolling by invitation - Clinical trials for Pulmonary Hypertension

Effects of Ground-based Walking Training in Pulmonary Hypertension

Start date: September 12, 2018
Phase: N/A
Study type: Interventional

Pulmonary Hypertension (PH) is a hemodynamic and physiopathological condition that is defined as an increase in pulmonary artery pressure ≥25 mmHg when measured at resting with symptoms such as dyspnea, fatigue, chest pain, and syncope. PH characterized by decreased exercise capacity, quality of life, peripheral muscle strength, balance, and physical inactivity. It is recommended that patients with PH should be included in cardiopulmonary rehabilitation programs in addition to medical treatment. Ground-based walking training is a safe and effective method for COPD patients. In the literature, there are no studies evaluating the effects of ground-based walking training in PH patients. The aim of this project is to determine the effect of ground-based walking training on physical activity, exercise capacity, balance, peripheral muscle strength and quality of life in patients with PH.

NCT ID: NCT03742544 Enrolling by invitation - Hypertension Clinical Trials

Post Marketing Surveillance of Telostop TAB (Telmisartan/Rosuvastatin) for Evaluating the Safety and Efficacy

Start date: June 23, 2015
Phase:
Study type: Observational

Post-marketing surveillance of Telostop TAB (Telmisartan/Rosuvastatin)

NCT ID: NCT03729323 Enrolling by invitation - Clinical trials for Type 2 Diabetes Mellitus

Motivational Interviewing in the Control of Arterial Hypertension and Type 2 Diabetes Mellitus

Start date: April 11, 2018
Phase: N/A
Study type: Interventional

The goal of this study is to evaluate the effectiveness of Nursing Consultation based on the assumptions and techniques of Motivational Interviewing for the control of Type 2 diabetes mellitus with associated diagnosis of Systemic Arterial Hypertension in primary healthcare.

NCT ID: NCT03719703 Enrolling by invitation - Hypertension Clinical Trials

Health in Childhood Following Assisted Reproductive Technology

HiCART
Start date: November 2018
Phase:
Study type: Observational [Patient Registry]

The purpose of this trial is to investigate the metabolic and cardiovascular health in children aged 6-8 years born after in-vitro fertilization with frozen embryo transfer

NCT ID: NCT03707561 Enrolling by invitation - Clinical trials for Pulmonary Hypertension

RUS-registry of PH

Start date: January 2016
Phase:
Study type: Observational [Patient Registry]

Russian National Registry of Patients With Pulmonary Arterial Hypertension (PAH) and Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a multicenter, observational study of the clinical course and disease management of PAH and CTEPH patients. designed to gather demographic, clinical and prognostic data of routine medical care in prospective manner for newly initiated treatment since Jan 2016. The internet-based registry (www.medibase.pro) fulfills high quality standards through several measures (planned minimum centre contribution of at least 10 patients per year, automated plausibility checks of data at entry, queries, monitoring with source data verification in >50% of participating centers). All consecutive patients diagnosed with World Health Organization Pulmonary Hypertension Groups (WHO Group I) PAH according to specific hemodynamic criteria will be enrolled in participating centers after signing the informed consents. Participating patients will be followed for a minimum of five years from the time of enrollment. It can be applied, among further purposes, for quality assurance: individual centers can confidentially compare their results with the combined outcome of the other centers. It is expected that the registry contributes to optimization of specific drug therapy for PAH and Pulmonary Hypertension (PH).

NCT ID: NCT03683186 Enrolling by invitation - Hypertension Clinical Trials

A Study Evaluating the Long-Term Safety and Efficacy of Ralinepag in Subjects With PAH Via an Open-Label Extension

Start date: September 2018
Phase: Phase 3
Study type: Interventional

Study APD811-303, ADVANCE EXTENSION, is an open-label extension (OLE) study for participants with WHO Group 1 PAH who have participated in another Phase 2 or Phase 3 study of ralinepag.

NCT ID: NCT03677609 Enrolling by invitation - Hypertension Clinical Trials

Stanford Clinics Physician Mindset Training

Start date: January 4, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to test the efficacy of a novel intervention for physicians to increase awareness about interacting with patients with pre- diabetes, diabetes, and hypertension. The investigators will measure health outcomes in patients as well as patient and physician satisfaction at Stanford Corporate clinics. The doctor-patient relationship has been shown to positively impact not only patient satisfaction, but also patients' physiological health outcomes. Thus, the investigators hypothesize that improving the patient-provider relationship would increase physician efficacy in regards to communicating and mitigating long-term risks to patients at risk for or suffering from chronic illness. The present study develops and tests a mindset intervention for physicians aimed at helping physicians prioritize connecting with their patients both in addition to and in comparison with a communication skills training for physicians.