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Hypertension clinical trials

View clinical trials related to Hypertension.

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NCT ID: NCT03885843 Not yet recruiting - Clinical trials for Cardiovascular Diseases

Sympathetic Mapping/ Ablation of Renal Nerves Trial (SMART) HTN-OFF MED Study

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

To evaluate the efficacy and safety of selected renal sympathetic denervation using SyMapCath I™ Catheter and SYMPIONEER S1™ Stimulator/Generator in patients with hypertension in the absence of antihypertensive medications, or till the negative result was given by urinary antihypertensive drugs detection of high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) after at least two weeks of drug elution period. Then Office systolic blood pressure (SBP) is still ≥ 150mmHg, < 180mmHg, diastolic blood pressure (DBP) ≥ 90mmHg, and 24-hour mean SBP of ambulatory blood pressure measurement (ABPM) is ≥130mmHg, or day-time mean SBP ≥135mmHg, or night-time mean SBP ≥120mmHg, and all SBP of ABMP record <170mmHg. After then the patient will be included when the results of bilateral renal angiography meet the requirements of renal nerve stimulation, mapping and denervation conditions.

NCT ID: NCT03884465 Not yet recruiting - Clinical trials for Pulmonary Arterial Hypertension

Hemodynamic Evaluation of Dose-response and Safety of Dry Powder Inhalation of Treprostinil

Start date: May 30, 2019
Phase: Phase 2
Study type: Interventional

Acute and chronic hemodynamic dose-response and safety evaluation of LIQ861 in PAH subjects.

NCT ID: NCT03883048 Recruiting - Bronchiectasis Clinical Trials

Analysis of the Severity and Prognosis of Pulmonary Hypertension Associated With Bronchiectasis.

Start date: June 1, 2018
Study type: Observational

Through analysis of demographic factors (gender, age, smoking history, body mass index), clinical indicators (signs and symptoms), sputum culture results (pseudomonas aeruginosa), Brain Natriuretic Peptide and imaging (scope and type of Bronchiectasis), pulmonary function index, inflammatory cytokines and inflammasome of patients, some factors will be found which maybe be related to severity and prognosis of Pulmonary Hypertension Associated With Bronchiectasis.

NCT ID: NCT03881657 Completed - Obesity Clinical Trials

Reverse Colocated Integrated Care Intervention Among Persons With Severe Persistent Mental Illness at US-Mexico Border

Start date: November 24, 2015
Phase: N/A
Study type: Interventional

This study evaluated whether patients with severe and persistent mental illness (SPMI) who received coordinated co-located behavioral health and primary care services were more likely to improve health outcomes after 12 months compared to SPMI patients who receive only behavioral health services from the local mental health authority (LMHA) Tropical Texas Behavioral Health (TTBH).The study employed a randomized control trial (RCT) design where intervention participants receiving integrated behavioral health were compared to control participants receiving the usual care provided within an LMHA for SPMI patients. Patients were placed in each group using a randomized number process. Demographic and health outcome data were collected from intervention and control participants at baseline. Health outcome data was subsequently collected at 6-month and 12-month follow-up points.

NCT ID: NCT03878290 Recruiting - Obesity Clinical Trials

RiSE to Prevent Cardiovascular Disease in African Americans

Start date: August 3, 2017
Phase: N/A
Study type: Interventional

The purpose of this pilot study is to evaluate an innovative 8-wk stress reduction program called Resilience, Stress and Ethnicity (RiSE) program designed to reduce chronic stress associated with perceived discrimination among African Americans. African Americans residing in the Maywood community between the ages of 25 and 75 with at least one cardiovascular disease risk factor such as being overweight, having high blood pressure, or diabetes will be enrolled. The following specific aims will be addressed: Aim 1: Determine the feasibility and acceptability of the program as a strategy to reduce chronic stress in African Americans within the Maywood and surrounding community. Aim 2: Examine the extent to which training in RiSE (1) improves psychological well being, (2) decreases inflammatory burden, and (3) reduces cardiovascular risk in African Americans Participants will be randomized to either the RiSE program or the control (no intervention group). Participants will provide blood and saliva samples as well as complete written questionnaires asking them questions about their health, well-being, and early life at the start of the study, half way through the study (at 4 weeks), at the completion of the intervention (8 weeks) and 3 months after the completion of the intervention).

NCT ID: NCT03877692 Recruiting - Clinical trials for Chronic Hypertension in Obstetric Context

Acute Control of Chronic Hypertension

Start date: February 18, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this study is to understand if administration of a personalized dose of the anti-hypertensive medication, labetalol, based on patient's history of preexisting hypertension, will be more effective at controlling severe hypertension during pregnancy, compared to the current standard dosing.

NCT ID: NCT03876509 Recruiting - Clinical trials for Pulmonary Hypertension

Non-invasive Diagnosis of Pulmonary Hypertension by Impedance Cardiography

Start date: July 4, 2018
Study type: Observational

The goal of the study is to prospectively evaluate Impedance Cardiography as a tool to detect pulmonary hypertension. According to our hypothesis Impedance Cardiography is a valuable method to differentiate patients without pulmonary hypertension from patients with pulmonary hypertension. The main objective is to determine the sensitivity and specificity in comparison to the gold standard right heart catheterization.

NCT ID: NCT03876418 Not yet recruiting - Clinical trials for Intra-Abdominal Hypertension

Surveillance, Prevention and Treatment of Intra-abdominal Hypertension and Abdominal Compartment Syndrome

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

This study evaluates the efficacy of intensive surveillance, prevention and treatment of intra-abdominal hypertension in ICU patients. In the first two months patients will be screened and undergo usual care. In the following 10-months patients will have more intensive screening and active measures towards prevention and treatment according to best practices.

NCT ID: NCT03875768 Not yet recruiting - Hypertension Clinical Trials

Dash Cloud Digital Trial

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

This trial will examine the effects of the intervention on changes in dietary quality and blood pressure among men and women with high blood pressure, using the new blood pressure guidelines for non-pharmacological treatment. The primary outcome is 6-month change in DASH (Dietary Approaches to Stop Hypertension) adherence, as measured by 24-hour recalls. DASH adherence will be measured at 12-months post-randomization. Secondary outcomes include changes in blood pressure and other physiological outcomes (e.g. weight, lipids, glucose).

NCT ID: NCT03874754 Not yet recruiting - Hypertension Clinical Trials

Tailored Home-Based Exercise Program for Multiple Chronic Conditions

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

A home-based, tailored, technology-enhanced home-based exercise program (iHBE) using a combination of the integrated mobile technologies (wearable device and phone application) and tailored home-based exercise will be pilot tested. Participants will choose one of the four home-based exercise options [National Institute of Aging (NIA) Go4Life (an exercise and physical activity campaign from the NIA), Iyengar-style yoga, walking, and modified Otago exercise] based on participants' preference and goals. The integrated mobile technologies system will allow the investigators to extract heart rate data directly from the wearable device to the research server. This data will be used to provide appropriate and personalized feedback on physical performance. The survey and notification to the participants on the smartphone.