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Arterial Hypertension clinical trials

View clinical trials related to Arterial Hypertension.

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NCT ID: NCT03512106 Not yet recruiting - Clinical trials for Arterial Hypertension

The Efficacy of the Acupuncture in the Treatment of Systemic Arterial Hypertension

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

There are few studies in the treatment of hypertension employing acupuncture as a blood pressure regulating technique. The Ministry of Health synthesized the inclusion of integrative and complementary practices within the Unique Health System, such as acupuncture. Our objective is to verify the effect of the acupuncture session on hypertensive patients, measured through ambulatory blood pressure monitoring (ABPM). In this way two groups of patients will be selected in a randomized clinical trial. In the first group, Chinese traditional acupuncture will be applied and in the second group the acupuncture sham will be applied.

NCT ID: NCT03504124 Not yet recruiting - Clinical trials for Arterial Hypertension

Multicomponent Intervention to Improve Hypertension Control in Central America

Start date: November 2018
Phase: Phase 3
Study type: Interventional

The investigators propose to assess the needs, barriers, and knowledge gaps of hypertension control programs in the national health care systems of the Central America 4 region LMIC (CA-4: Guatemala, Honduras, El Salvador, and Nicaragua); to conduct a cluster randomized trial to test the effect of a multilevel and multicomponent intervention program leveraging an existing subnational primary healthcare system in Guatemala, on blood pressure (BP) control among hypertensive patients; and to evaluate the adaptability, feasibility, fidelity, and sustainability of implementing the program in the primary health care systems of the CA-4 region. The comprehensive intervention, which includes protocol-based treatment using a standard BP management algorithm, team-based collaborative care, BP audit and feedback, home BP monitoring, and health coaching on antihypertensive medication adherence and lifestyle modification, will last for 18 months. This implementation research study presents high public health impact because it will generate urgently needed data on effective, practical, and sustainable intervention strategies aimed at reducing BP related disease burden in Central America and other low- and middle-income countries.

NCT ID: NCT03294070 Not yet recruiting - Clinical trials for Arterial Hypertension

Fimasartan Plus Amlodipine on Hemodynamic Parameters and Arterial Stiffness in Patients With Hypertension

Start date: September 2017
Phase: Phase 4
Study type: Interventional

24-week open clinical trial to assess tolerability and effect on pressure, hemodynamic parameters and arterial rigidity of the combined treatment based on Fimasartan 60 mg and amlodipine besylate 5 mg given once daily in patients with arterial hypertension in stages 2-3

NCT ID: NCT03282942 Not yet recruiting - Clinical trials for Arterial Hypertension

Cardiovascular Effects of Aerobic and Strength Training in Hypertensive Middle-aged Individuals

Start date: June 2, 2018
Phase: N/A
Study type: Interventional

Systemic arterial hypertension (SAH) is characterized by elevated and sustained blood pressure levels, related to several risk factors. Modifying lifestyle to combat risk factors associated with cardiovascular disease is critical, as such factors are related alteration of endothelial vasodilator response leading to progressive loss of its protective function. However, endothelial dysfunction related to hypertension is not only related to the decrease in the bioavailability of endothelium relaxants, but also to the time of presence of hypertension, increased production of vessel contraction factors and oxidative stress related to the disease. In this way, physical training presents as a non-drug strategy capable of directly and indirectly influencing the pathophysiology of hypertension. In this way the objective of the present work will be to evaluate the acute and chronic effect of aerobic exercise and strength on blood pressure, blood markers of vasodilation and vascular endothelial vasoconstriction, as well as the repercussion on flow-mediated dilatation and oxidative stress markers, In middle-aged hypertensive individuals before and after 12 weeks of training. Study hypothesis: The expected results of the research are that the endothelial response of biochemical markers of vasodilation and vasoconstriction will change positively after aerobic and strength training and the responses will be similar when compared between groups. There will be an improvement in the antioxidant capacity in both groups and the magnitude of the hypotensive effect will be greater in the aerobic group when compared to control and strength.

NCT ID: NCT03243045 Recruiting - Clinical trials for Arterial Hypertension

Systemic Microvascular Function in Patients With Resistant Hypertension After Renal Sympathetic Denervation

Start date: March 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

It has been proposed that the modulation of the activity of the sympathetic nervous system, through renal sympathetic denervation, besides reducing blood pressure, would promote an improvement in vascular reactivity and consequent improvement of macro and microcirculation. The present study aimed to investigate the influence of the renal sympathetic denervation on the skin microvascular function of patients presenting with resistant arterial hypertension.

NCT ID: NCT03160989 Completed - Clinical trials for Arterial Hypertension

Acute and Chronic Responses to Blood Pressure After Exercise

Start date: May 2016
Phase: N/A
Study type: Interventional

The study will evaluate the variability of blood pressure in postmenopausal and hypertensive women after only one session and after training of ten weeks of combined physical exercises (aerobic and resisted).

NCT ID: NCT03094702 Completed - Clinical trials for Arterial Hypertension

SPRINT Trial Type Blood Pressure Measurements in Patients After Kidney Transplantation

Start date: January 1, 2017
Phase: N/A
Study type: Observational

The SPRINT study used a blood pressure measurement procedure that differs from earlier studies in arterial hypertension. SPRINT type readings are lower than regular office measurements. The extent of the disagreement between SPRINT and office measurements may differ in distinct patient groups. This difference is not yet known for patients after renal transplantation. However, it is important to know the difference in order to apply SPRINT findings to transplant recipients.

NCT ID: NCT03049709 Completed - Diabetes Mellitus Clinical Trials

Non-invasive Validation of Non-invasive Central Blood Pressure Measurements Using Oscillometric Pulse Wave Analysis

MEASURE-cBP2
Start date: May 1, 2015
Phase: N/A
Study type: Observational

There is growing evidence that central blood pressure is a better predictor of hypertensive end-organ damage and cardiovascular outcome than routine brachial readings. The investigators aimed to evaluate the accuracy of a novel device for the non-invasive determination of central blood pressure based on automated oscillometric radial pulse wave analysis.

NCT ID: NCT03047538 Recruiting - Blood Pressure Clinical Trials

Fixed Combination for Lipid and Blood Pressure Control

FILIP
Start date: September 1, 2017
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare the effect of fixed and free combination of atorvastatin/perindopril/amlodipine on blood pressure and lipid levels.

NCT ID: NCT03046264 Completed - Clinical trials for Coronary Heart Disease

Invasive Validation of Non-invasive Central Blood Pressure Measurements Using Oscillometric Pulse Wave Analysis

MEASURE-cBP1
Start date: September 1, 2013
Phase: N/A
Study type: Observational

There is growing evidence that central blood pressure is a better predictor of hypertensive end-organ damage and cardiovascular outcome than routine brachial readings. The investigators aimed to evaluate the accuracy of a novel device for the non-invasive determination of central blood pressure based on automated oscillometric radial pulse wave analysis.