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Filter by:The purpose of this study is to understand if ARV-471 affects how a medicine called, dabigatran etexilate, gets absorbed or processed into the body in healthy adults. All participants in this study will receive one dose of dabigatran etexilate alone by mouth in Period 1. In Period 2, everyone will receive one dose of dabigatran etexilate by mouth approximately 90 minutes after receiving one dose of ARV-471 by mouth. The levels of dabigatran in Period 1 will be compared to the levels of dabigatran in Period 2. This will help us to determine if and how ARV-471 affects dabigatran gets absorbed into the body differently in healthy adults. All participants will stay at the study clinic for approximately 8 days and 7 nights.
The purpose of this study is to document the utility of the Vivio System in quantifying LVDP in healthy volunteers.
The goal of this study is to assess the safety and tolerability of single and multiple ascending doses of XEN-101
This study will investigate the test-retest reliability of transcranial magnetic stimulation (TMS) -evoked potentials (TEPs) as measured by electroencephalography (EEG), using three different TMS protocols over five different brain regions in healthy volunteers. The goal is to compare the test-retest reliability of single pulse, inhibitory and excitatory TMS protocols as well as two distinct targeting approaches. The main questions to answer are: 1. This study will investigate whether the test-retest reliability of TEPs differ across TMS protocols. 2. This study will investigate whether the test-retest reliability of TEPs differ between individualized and non-individualized targeting approaches.
The main purpose of this study is to evaluate the safety and immunogenicity of three dosage levels (low, medium, high) of the bivalent combination respiratory syncytial virus (RSV)/human metapneumovirus (hMPV) virus-like particle (VLP) candidate vaccine (IVX-A12), compared to placebo, when administered as a single-dose regimen in healthy older adults 60 to 75 years of age.
The aim of this randomized controlled study, which included pre-test, posttest and perseverance test, was to determine the effect of game-based learning on nursing students' knowledge levels about blood transfusion, to determine the permanence level of learning and satisfaction with the training method. The fundamental question it aims to answer is: •Does the blood transfusion training given to nursing students by the board game playing method have an effect on the level of knowledge, the permanence of the information and satisfaction with the training method? Participants will participate in an educational activity related to blood transfusion. The researchers will compare whether the blood transfusion training given to nursing students with the board game playing method is effective or not with the text-reading method.
The goal of this randomized controlled including pretest, posttest and persistence test study is to examine the effect of creative drama method on student nurses' knowledge and skill levels related to postmortem care, learning permanence and satisfaction with the training method. The main question it aims to answer are: •Is the postmortem care training given to nursing students with the creative drama method effective on the level of knowledge and skills, the permanence of knowledge and skills and satisfaction with the training method? Participants will participate in an educational activity related to postmortem care. Researchers will compare it with the classical education method to see if postmortem care training given to nursing students with the creative drama method is effective.
The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 765423 in healthy male subjects following intravenous administration of single rising doses.
The goal of this clinical trial is to evaluate the effect of Product X on facial skin of middle-aged women in Malaysia. The main questions it aims to answer are: 1. The effect of Product X on skin hydration of middle-aged women in Malaysia. 2. The effect of Product X on skin elasticity of middle-aged women in Malaysia. 3. The effect of Product X on skin wrinkle of middle-aged women in Malaysia. 4. To observe any adverse effect occurrence with the use of Product X. Participants will used Product X for 8 week and the skin assessment will be carried out at baseline, week 2, 4 and week 8.
This study is the first clinical study with PF-07328948. The safety, tolerability, and plasma pharmacokinetics and pharmacodynamics of PF-07328948 after administration of escalating, single, oral doses will be evaluated.