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Healthy clinical trials

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NCT ID: NCT05693948 Completed - Healthy Clinical Trials

The Efficacy of Topical Serum X for Skin Brightening

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

This study is conducted to evaluate the effectiveness of topical serum X containing arbutin and glutathione for skin brightening. The study duration is 12 weeks and the skin assessment will be carried out at baseline, week 4, 8 and week 12.The main questions this study aims to answer are: 1. The skin brightening effect of the product on facial skin. 2. To observe any adverse effect occurrence with the usage of the product.

NCT ID: NCT05692869 Completed - Healthy Clinical Trials

A Study of Continuous Blood Pressure Monitoring in Healthy Participants

Start date: January 31, 2023
Phase: N/A
Study type: Interventional

The main purpose of this study in healthy participants is to find out whether the traditional ambulatory blood pressure monitor (ABPM) and newer wearable devices (EmbracePlus smartwatch device, Biobeat chest patch device, and Aktiia wrist device) will accurately pick up changes in blood pressure caused by 2 different medications (propranolol and pseudoephedrine). The study will last about 29 days excluding the screening period of 28 days.

NCT ID: NCT05691777 Completed - Healthy Clinical Trials

Study of Cortical Activation During Hand and Shoulder Movements in Healthy Subjects

CouNirs
Start date: June 25, 2020
Phase:
Study type: Observational

Characterization of cortical activation patterns during movements in healthy adults may help our understanding of how the injured brain works. Upper limb motor tasks are commonly used to assess impaired motor function and to predict recovery in individuals with neurological disorders such as stroke. This study aimed to explore cortical activation patterns associated with movements of the hand and shoulder using functional near-infrared spectroscopy (fNIRS). The investigators hypothesized that the activation pattern observed with fNIRS would differ for shoulder and hand movements. More specifically, the investigators hypothesized that the cerebral activation during hand movements would mainly involve the contralateral hemisphere, particularly the lateral part of primary motor cortex; whereas activation during shoulder movements would be more medial and more extensive than that of the hand.

NCT ID: NCT05691413 Completed - Healthy Clinical Trials

Safety and Efficacy of Facial Cleanser

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

This study is conducted to evaluate the safety and effectiveness of facial cleanser X containing combination of olive oil, virgin coconut oil, butylene glycol and hyaluronic acid on skin hydration and skin elasticity. The study duration is 5 weeks and the skin assessment will be carried out at baseline, week 3 and week 5.The main questions this study aims to answer are: 1. The effect of product on skin hydration. 2. The effect of product on skin elasticity. 3. To observe any adverse effect occurrence with the usage of the product.

NCT ID: NCT05688397 Completed - Healthy Clinical Trials

Evaluation of the Vaginal Colonization of Two New Lactobacillus Strains After Oral Administration in Healthy Volunteers

Start date: February 15, 2023
Phase: N/A
Study type: Interventional

Randomized study to determine whether the vaginally isolated strains of Lactobacillus gasseri and/or Lactobacillus crispatus can colonize the vagina when taken orally for 18 days. Secondary outcomes comprise evaluation of safety, tolerability, impact on vaginal microbiota and vaginal pH

NCT ID: NCT05685264 Completed - Healthy Clinical Trials

A Study to Learn How the Study Medicine (Ponsegromab) is Changed and Eliminated From Healthy Chinese Adults

Start date: January 18, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this clinical trial is to learn about the safety of the study medicine (ponsegromab) and how it undergoes change and elimination in healthy Chinese adults. This study is seeking male and female Chinese participants who are very healthy as confirmed after some medical tests. All participants in this study will receive Ponsegromab only once: - for half of the participants, ponsegromab will be given as a shot in the front of the thigh, abdomen, or outer area of the upper arm at the study clinic. - for another half of the participants, ponsegromab will be given as four shots in the front of the thigh, abdomen, or outer area of the upper arm at the study clinic. We will measure the amount of the study medicine in the blood of the participants after giving the shots. Later we will examine experiences of people receiving the study medicine. This will help us understand how the medicine is changed and eliminated from your body and to decide if the study medicine is safe. Participants will take part in this study for 22 weeks. During this time, they will stay at the study clinic for the first 8 days and will visit the study clinic about 8 times.

NCT ID: NCT05684640 Completed - Healthy Clinical Trials

A Single and Multiple Dose of Rodatristat Ethyl in Healthy Adult Subjects to Evaluate the Effect of Food and Safety

Start date: September 29, 2022
Phase: Phase 1
Study type: Interventional

This is a single and multiple dose food effect study of rodatristat ethyl in healthy subjects

NCT ID: NCT05680857 Completed - Healthy Clinical Trials

Efficacy and Safety of Products Containing Marine Collagen Peptide and Coenzyme Q10 for Skin Rejuvenation

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

This is a placebo-controlled study conducted to investigates the safety and efficacy of products containing marine collagen peptide and CoQ10 in enhancing skin rejuvenation of Malaysian women. The study duration is 28 days and the skin assessment will be carried out at baseline, Day 14 and Day 28.The main questions it aims to answer are: 1. The effect of product on skin hydration of women in Malaysia. 2. The effect of product on skin elasticity of women in Malaysia. 3. The effect of product on skin wrinkle of women in Malaysia. 4. The skin brightening effect of product on Malaysian women. 5. To observe any adverse effect occurrence with the consumption of the product.

NCT ID: NCT05674669 Completed - Healthy Clinical Trials

A Dose-Ranging Study of 50 µg to 100 µg LSD in Healthy Volunteers

Start date: October 20, 2015
Phase: Phase 1
Study type: Interventional

This study with low-dose LSD comprised 2 substudies in healthy subjects. Subjects who met all inclusion and no exclusion criteria provided written informed consent. Part 1 was an open-label dose-escalation study in hallucinogen non-naïve subjects with significant prior experience with hallucinogens, during which each subject received a single dose of LSD: 50, 75, or 100 µg. Part 2 was a double blind, placebo controlled, randomised, crossover study in hallucinogen naïve subjects with no prior experience with hallucinogens in the last 7 years, during which each subject was assigned to 1 of 8 cohorts and then randomly assigned to receive single doses of LSD 50 µg followed by 75 µg, or placebo followed by 75 µg, with dosing separated by at least 7 days. Subjects were followed up on the day after each dosing, and 1 week and 1 month after the last dose of study treatment. A total of 32 subjects were enrolled.

NCT ID: NCT05674136 Completed - Healthy Clinical Trials

Clinical Equivalence of Masimo INVSENSOR00061 to RD SET Neo

Start date: November 18, 2022
Phase: N/A
Study type: Interventional

This study is designed to compare the equivalence of the Masimo INVSENSOR00061 to RD SET Neo for SpO2 and performance of PR and RRp as the subjects undergo a controlled desaturation protocol. This type of study design is required to evaluate the performance of pulse oximeters based upon the ISO 80601-2-61 standard which is also adopted and referenced by the FDA.