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Stroke clinical trials

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NCT ID: NCT03394339 Active, not recruiting - Stroke Clinical Trials

Meta-analysis of Fruit and Vegetable Sources and Cardiovascular Outcomes

Start date: April 1, 2017
Phase: N/A
Study type: Observational

Fruit and vegetables are a cornerstone of healthy dietary patterns and dietary guidelines worldwide. The supporting evidence, however, is largely derived from observational studies of protective associations with cardiovascular disease (CVD) in health-conscious populations or from randomized trials of the effect of specific fruit or vegetable derived nutrients on CVD risk factors. A growing body of literature has influenced a shift away from a focus on single nutrients to a focus on whole foods and dietary patterns. To what extent fruit and vegetables should contribute to dietary patterns for cardiovascular health and whether specific types of fruit or vegetables should be recommended is unclear. Although previous systematic reviews and meta-analyses have elucidated the association between the intake of total and some specific fruit and vegetables with cardiovascular outcomes, a comprehensive synthesis comparing the certainty of the evidence for the different types of fruit and vegetables in relation to a range of cardiovascular outcomes has yet to be completed. We propose to conduct a systematic review and meta-analysis of the available prospective cohort studies using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the association between different types of fruit and vegetables and different cardiovascular outcomes that include CVD, coronary heart disease [CHD], and stroke incidence and mortality.

NCT ID: NCT03392792 Not yet recruiting - Clinical trials for All Patients With Ischemic Cerebrovascular Stroke Aged =18 Years of Both Sex

Regisry of the Stroke Patients in Assiut University Hospital

Start date: December 30, 2018
Phase: N/A
Study type: Interventional

• Aim of the work To register all type of acute stroke admitted in Assiut university Hospital and assessment of their risk factor, morbidity and Mortality

NCT ID: NCT03392519 Recruiting - Chronic Stroke Clinical Trials

Brain Imaging Study of Brain Plasticity in Chronic Stroke Patients

Start date: August 18, 2015
Phase: N/A
Study type: Observational

In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.

NCT ID: NCT03392493 Recruiting - Stroke Clinical Trials

Robot-assisted Hand Rehabilitation for Patients With Stroke

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

Robotic therapy can deliver larger amounts of upper extremity movement practice for stroke rehabilitation. Although the treatment effects were supported in studies, there are still limitations in clinical intervention. The study will use the robot-assisted hand rehabilitation with a Gloreha device. Thirty patients with moderate motor deficits were recruited and randomized into 2 treatment groups, AB or BA (A = 12 times of robot-assisted hand rehabilitation, B = 12 times of standard therapy) for 12 weeks of treatment (Sixty minutes a time, twice a week), 1 month of break between conditions for washout period. The performance was assessed by a blinded assessor for five times (pre-test1, post-test 1, pre-test2, post-test 2, follow up at three month). The outcome measures Fugl-Meyer Assessment-Upper Limb section(FMA-UE),Box and block test(BBT), Maximal voluntary contraction(MVC) of extensor digitorum communis(EDC), Abductor pollicis brevis(APB), Flexor digitorum(FD), Dynanometer, Semmes-Weinstein hand monofilament (SWM), Revision of the Nottingham Sensory Assessment (EmNSA), Modified Barthel Index. Collected data will be analyzed with ANOVA test by SPSS version 20.0, and alpha level was set at 0.05. The hypothesis are robot-assisted hand rehabilitation with a Gloreha device has positive effects on sensory, motor, hand function, and ADL ability among patients with stroke.

NCT ID: NCT03391713 Not yet recruiting - Stroke, Acute Clinical Trials

The Effectiveness of Waiting Room Posters for Stroke Education

Start date: January 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effectiveness of posters in improving patient awareness and knowledge of the signs and symptoms of stroke. The control group study will be conducted in the first two weeks. Subsequently, the intervention arm will occur in the subsequent two weeks.

NCT ID: NCT03391102 Recruiting - Stroke Clinical Trials

Matão Preventing Stroke (MaPS): a Stroke Register Study

Start date: August 2015
Phase: N/A
Study type: Observational [Patient Registry]

Stroke is one of the most important cause of mortality and disability in Brazil. The city of Matão, located in São Paulo state, with a population around 80.000 inhabitants, has conditions to develop a community-based stroke study, which can answer important questions regarding epidemiological data over the time. Therefore, the purpose of this prospective community based study is to observe trends in stroke incidence, types and sub-types of stroke, risk factors, prognosis, 30 days and one year case-fatality during a follow-up of ten years. This study offers the opportunity to conduct an epidemiological study of high quality which can obtain data to formulate public politics to reduce the social and economic impact of stroke in Brazil.

NCT ID: NCT03390192 Recruiting - Stroke Clinical Trials

Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Stroke

Start date: January 13, 2015
Phase: N/A
Study type: Interventional

Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability. Recently, more challenging approaches, such as stimulation of two or more sites or use of dual modality have been studied in stroke patients. In this study, simultaneous stimulation using both inhibitory rTMS (1Hz) and anodal tDCS (dual-mode stimulation) over bilateral primary motor cortices (M1s) was investigated to compare its modulatory effects with single inhibitory rTMS stimulation in subacute stroke patients.

NCT ID: NCT03389529 Not yet recruiting - Clinical trials for Coronary Artery Disease

the Change of Cholesterol Efflux Capacity and Coronary Artery Disease in Real Clinical Practice

Start date: March 1, 2018
Phase: N/A
Study type: Observational

The purpose of this study is to investigate the change of cholesterol efflux capacity in patients with coronary artery disease treated with secondary prevention drugs, and the correlation with the prognosis.

NCT ID: NCT03387267 Recruiting - Stroke Clinical Trials

Videofluoroscopic Swallowing Study (VFSS)

Start date: October 24, 2017
Phase: N/A
Study type: Interventional

The study procedure of simultaneous VFSS and DDS measurement will be completed in one day and the subject will be followed within 2 business days after the study procedure to monitor for adverse events.

NCT ID: NCT03385928 Not yet recruiting - Clinical trials for Intracerebral Haemorrhage

STOP-AUST Ambulance: Stopping Haemorrhage With Tranexamic Acid cOmmenced Prehospital - AUSTralia in a Mobile Stroke Ambulance.

Start date: January 12, 2018
Phase: Phase 2
Study type: Interventional

The study will be prospective phase II randomised, double-blind, placebo-controlled, investigator-driven trial in acute intracerebral haemorrhage patients. The study has 2 arms with 1:1 randomisation to either intravenous Tranexamic acid or placebo and will test the hypothesis that ICH (intracranial haemorrhage) patients treated with intravenous tranexamic acid within 2 hours of symptom onset will have lower rates of haematoma growth than compared to placebo.