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Stroke clinical trials

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NCT ID: NCT03622606 Not yet recruiting - Stroke Clinical Trials

Development and Validation of a Language Screening Test in Acute Right Hemispheric Strokes

R-LAST
Start date: September 2018
Phase: N/A
Study type: Interventional

This is a bi-centric study whose main objective is the validation of a rapid screening test for language disorders in the acute phase of right hemisphere stroke. Primary objective The main objective is the validation of a rapid language disorder screening tool that will be used in the acute phase of right hemispheric stroke. Secondary objectives Secondary objectives are: - Characterize the "atypical crossed aphasia" since the acute phase of stroke with a large cohort of patients , which, to our knowledge, has never been done. - Re-evaluate the number of patients with acute language disorder in right hemisphere stroke. - Validate the use of R-LAST by different categories of carers

NCT ID: NCT03622515 Not yet recruiting - Clinical trials for Transient Ischemic Attack

the Research of the Cerebral Protection Effects of Electroencephalogram (SedLine) During Carotid Endarterectomy

Start date: July 30, 2018
Phase: N/A
Study type: Interventional

Fragile brain is the most common phenomenon seen in the patients undergoing CEA. The patients with fragile brain have a high incidence of postoperative brain dysfunction. This study intends to apply EEG monitoring (Sedline) to CEA to investigate whether EEG monitoring can reduce the incidence of postoperative neurological complications in CEA patients and improve their prognosis. 220 patients with CEA were randomly divided into 2 groups. Group S [Sedline monitoring + Transcranial Doppler (TCD) + regional cerebral oxygen saturation (rS02),n=110] and group C [Bispectral index (BIS) + TCD +rSO2,n=110], recording intraoperative and postoperative conditions, neuropsychology scale assessment, blood examination and imaging examination. The incidence of postoperative neurological complications was compared between the two groups.

NCT ID: NCT03622411 Not yet recruiting - Stroke Clinical Trials

Tablet-based Aphasia Therapy in the Chronic Phase

Start date: September 3, 2018
Phase: N/A
Study type: Interventional

Aphasia is one of the most common and disabling disorders following stroke, in many cases resolving in long-term deficits. There is evidence that intensive aphasia therapy is effective for language recovery, even in the chronic phase post-stroke. However, as many patients are left with residual language disorders and intensive aphasia rehabilitation is difficult to achieve, the investigators are exploring tablet-based therapies to further facilitate language recovery in a cost-effective manner.

NCT ID: NCT03621917 Recruiting - Acute Stroke Clinical Trials

Evaluation of tPA Efficacy in Acute Stroke Patients With NIRS (Near-infrared Spectroscopy)

E-NESE
Start date: November 1, 2017
Phase:
Study type: Observational

Investigators aim to study efficiency of systemic thrombolytic therapy on acute ischemic stroke patients with near infrared spectroscopy.

NCT ID: NCT03621826 Enrolling by invitation - Sickle Cell Disease Clinical Trials

Evaluating Barriers to Stroke Screening and Prevention in Children With Sickle Cell Disease

DISPLACE
Start date: February 12, 2018
Phase:
Study type: Observational

DISPLACE is a three part, multi-center U.S. based study to evaluate the barriers to stroke screening and prevention in children with sickle cell anemia (SCA). In the United States, TCD (Transcranial Doppler ultrasound) is a proven method of screening children with SCA for stroke. However, many children are not getting the screening they need. This study will examine the issues that hinder and help children get the screening at 28 different hospitals and sickle cell centers to improve care for all children with sickle cell anemia. The investigators will then plan a study (part 3) aimed to improve stroke screening and prevention in sickle cell anemia.

NCT ID: NCT03620370 Not yet recruiting - Stroke, Acute Clinical Trials

Normobaric Hyperoxia Combined With Reperfusion for Acute Ischemic Stroke

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

NBO is a nonpharmacological measure of neuroprotection. The purpose of our study is to evaluate the safety and efficiency of NBO(Normobaric hyperoxia) in the acute ischemic stroke patients who received endovascular treatment. Looking for more clinical evidence for the ischemic stroke patients who will be treated with NBO in the future.

NCT ID: NCT03619772 Recruiting - Stroke Clinical Trials

EMG Training for Altering Activation Patterns After Stroke

Start date: June 28, 2018
Phase: N/A
Study type: Interventional

Evaluation of a new EMG controlled game to improve hand function in chronic stroke survivors.

NCT ID: NCT03619642 Completed - Stroke Clinical Trials

Reliability, Validity and Clinical Utility of a Robotic Assessment for Proprioception

Start date: December 15, 2017
Phase: N/A
Study type: Interventional

The aim of this case-controlled observational cross-sectional study is to investigate the test-retest reliability, validity and clinical utility of a rapid robotic assessment of finger proprioception using a passive gauge position matching tasks in MS and stroke subjects. Session 1 Informed consent Descriptive measures Session 2 Clinical testing Robotic assessment (3x) Session 3 Clinical testing Robotic assessment (3x)

NCT ID: NCT03618732 Completed - Stroke Clinical Trials

A Randomized Controlled Trial of Bilateral Movement-based Computer Games Training to Improve Motor Function of Upper Limb and Quality of Life in Sub-acute Stroke Patient

Start date: August 3, 2015
Phase: N/A
Study type: Interventional

This study aims at investigating whether bilateral movement-based training with computer games could augment motor function of paretic upper limb and improve quality of life in sub-acute stroke patients.

NCT ID: NCT03618290 Not yet recruiting - Stroke, Acute Clinical Trials

Plasma Free Fatty Acids Profile As A Diagnostic Tool For Acute Ischemic Stroke

Start date: August 30, 2018
Phase:
Study type: Observational

The purpose of the research is to use plasma free fatty acid profiling as a biomarker for ischemic stroke. The plasma free acid profile will be specifically and significantly changed in early stages upon stroke onset, and correlate with the stroke volume and progression determined by imaging techniques.