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Heart Failure clinical trials

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NCT ID: NCT03713333 Not yet recruiting - Hypertension Clinical Trials

Implementing Digital Health in a Learning Health System

ASE-INNOVATE
Start date: October 20, 2018
Phase: N/A
Study type: Interventional

The need for new models of integrated care that can improve the efficiency of healthcare and reduce the costs are key priorities for health systems across the United States. Treatment costs for patients with at least one chronic medical or cardiovascular condition make up over 4-trillion dollars in spending on healthcare, with estimations of a population prevalence of 100-million affected individuals within the next decade. Therefore, the management of chronic conditions requires innovative and new implementation methods that improve outcomes, reduce costs, and increase healthcare efficiencies. Digital health, the use of mobile computing and communication technologies as an integral new models of care is seen as one potential solution. Despite the potential applications, there is limited data to support that new technologies improve healthcare outcomes. To do so requires; 1) robust methods to determine the impact of new technologies on healthcare outcomes and costs; and 2) evaluative mechanisms for how new devices are integrated into patient care. In this regard, the proposed clinical trial aims to advance the investigator's knowledge and to demonstrate the pragmatic utilization of new technologies within a learning healthcare system providing services to high-risk patient populations.

NCT ID: NCT03710057 Completed - Clinical trials for Chronic Heart Failure

Effect of Ivabradine in Lowering Heart Rate and Quality of Life in Chronic Heart Failure Patients

Start date: December 1, 2016
Phase:
Study type: Observational

Elevated Heart rate (HR) (≥ 70 bpm) is one of the contributing factors in increasing the burden of hospitalization among Heart Failure patient. Ivabradine is a novel, selective and specific in inhibiting a Funny current in sinoatrial node Node and approved as an alternative therapy for Chronic Heart Failure (CHF) patients. CHF patients when treated with Ivabradine reported 39%, and 30% reduction in mortality and hospitalization rate respectively. Patient were treated with Ivabradine 5mg twice daily to determine its effect in lowering Heart rate and the Quality of Life (QOL) in Chronic Heart Failure patients

NCT ID: NCT03709160 Recruiting - Heart Failure Clinical Trials

Oral dIuretics in Very Intensive Treatment, an Early Intervention in Outpatients With Heart Failure

DIVINE
Start date: October 15, 2018
Phase: Phase 4
Study type: Interventional

In the present study, consecutive patients, older than 18 years, of both genders will be included. The diagnosis of reduced Heart Failure (HfrEF) according to: Clinical pattern, laboratories and Cardiac imaging (ESC criteria). Treatment will be assigned in two groups: Bumetanide and another group will be received Indapamide. Each group received maximum tolerated dose for seven days with Clinical and labs evaluations will be every 48 hrs. (Face-to-face and/or telephone visits). Serum and urinary labs, EKG´s, Echo will be evaluated. Daily in-home register will made. Final points were: Mortality, Urinary failure, Clinical Impairment, Hospital admissions, Oedema. (MUCHO). All patients will be followed for 30 days.

NCT ID: NCT03707275 Not yet recruiting - Heart Failure Clinical Trials

Personalized Voice Activated Wellness Assistants for Patients With Heart Failure

Start date: October 2018
Phase: N/A
Study type: Interventional

The Alexa+ Study will compare the use of the Amazon Echo Dot with Alexa voice technology in patients with chronic heart failure to those receiving standard of care heart failure management on changes in health and patient-centered outcomes.

NCT ID: NCT03705312 Not yet recruiting - Heart Failure Clinical Trials

MitraClip for the Treatment of Moderate Functional Mitral Regurgitation: EVOLVE-MR

EVOLVE-MR
Start date: October 2018
Phase: N/A
Study type: Interventional

This study evaluates the addition of transcatheter mitral valve repair with the MitraClip device to medical treatment in patients with heart failure and moderate functional mitral regurgitation to determine the impact of left ventricular remodelling and patients' functional capacity.

NCT ID: NCT03704220 Enrolling by invitation - Heart Failure Clinical Trials

Anti-thrombotic Monotherapy With the HeartMate 3 LVAS

Start date: August 16, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to obtain a single-center safety and feasibility data on patients managed with a single anti-thrombotic therapy and the incidence of thrombotic adverse events associated with HeartMate 3 LVAS therapy.

NCT ID: NCT03702062 Not yet recruiting - Heart Failure Clinical Trials

Dynamic Heart Failure Prediction With Real-time Functional Status Data in the Ambulatory Setting

Start date: May 2019
Phase: N/A
Study type: Interventional

Heart failure is the number one cause of hospital readmission in those over 65 years of age and the current standard-of-care of weight self-monitoring is inadequate to predict exacerbation. This project aims to improve the monitoring of heart failure disease progression through the use of real-time, up-to-date data obtained both from a smart phone-based tool and from the electronic health record. The goal is to develop a low-risk, clinically validated method to estimate dynamic heart failure risk to enable the provision of earlier, more effective outpatient interventions that decrease hospitalization.

NCT ID: NCT03701880 Active, not recruiting - Clinical trials for Heart Failure With Reduced Ejection Fraction

Early Use of Ivabradine in Heart Failure

Ivabradine
Start date: September 16, 2018
Phase: N/A
Study type: Interventional

The aim of the work is to Evaluate the efficacy, quality of life and safety of early addition of ivabradine to B-blocker in reduced EF heart failure patients after acute decompensation compared to the standard treatment.

NCT ID: NCT03701854 Completed - Clinical trials for Heart Failure Patients

Physical Impairments in Heart Failure Patients With Pacemakers

Start date: January 1, 2017
Phase:
Study type: Observational

Despite major breakthroughs that have recently been made in pacemakers implanted in heart failure (HF) patients, it is clear that functional impairments and symptoms often remain. However, only limited studies have investigated exercise capacity, muscle strength, pulmonary function, dyspnea, and fatigue in pacemaker implanted HF patients. Therefore, investigators aimed to compare the aforementioned outcomes in patients and healthy controls.

NCT ID: NCT03697980 Not yet recruiting - Clinical trials for Chronic Heart Failure

Apogee, Addendum to the Destination Therapy Post Approval Study (DT PAS)

Start date: October 22, 2018
Phase:
Study type: Observational [Patient Registry]

Medtronic is sponsoring the Apogee study to further enhance scientific understanding of the implant procedure, optimized blood pressure management, and anticoagulation/ antiplatelet therapy in patients receiving a Medtronic HeartWare™ Ventricular Assist Device (HVAD™) for destination therapy. The Apogee study is conducted within Medtronic's Product Surveillance Platform.