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Heart Failure clinical trials

View clinical trials related to Heart Failure.

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NCT ID: NCT03924479 Recruiting - Clinical trials for Heart Failure, Diastolic

Respiratory Muscle Function in Heart Failure

Start date: November 28, 2018
Phase: Phase 4
Study type: Interventional

This study is being done because investigators are trying to determine how respiratory muscle and lung function influence the exercise responses in heart failure and healthy participants. Further, the heart failure patients will participate in an intervention to improve their respiratory muscle function to determine if this improves exercise capacity.

NCT ID: NCT03924258 Not yet recruiting - Heart Failure Clinical Trials

Study of the Prevalence of Iron Deficiency in Patients With Heart Failure

CARENFER IC
Start date: May 15, 2019
Phase: N/A
Study type: Interventional

Despite its known prevalence in Heart Failure, a recent study conducted by Prof. Cacoub (unpublished) on the French national health insurance database showed that iron deficiency was a poorly diagnosed and poorly treated comorbidity. In chronic diseases including Heart Failure, Transferrin Saturation Factor is only performed in about 10% of cases while it is recommended for patients with Heart Failure (French Health High Authority 2011). The purpose of this study is to obtain current data on the prevalence of iron deficiency in France in patients with Heart Failure, applying the recommendations of European Society of Cardiology and French Health High Authority (determination of ferritinemia and Transferrin Saturation Factor).

NCT ID: NCT03924102 Not yet recruiting - Clinical trials for Acute Decompensated Heart Failure

Cardiac Perfusion and Metabolism With [11C] Acetate PET/CT is Associated With Hematopoietic System Activation in Acute Decompensated Heart Failure: An Imaging Sub-study

Start date: October 31, 2019
Phase: Phase 1
Study type: Interventional

The purpose of this sub-study is to use positron emission tomography and computed tomography imaging (PET/CT) with an investigational drug called [11C] acetate to see if inflammation in patients with acute decompensated heart failure (ADHF) can cause changes in blood flow and oxygen use in the heart. This study may help physicians better understand how to treat patients diagnosed with ADHF in the future.

NCT ID: NCT03923673 Not yet recruiting - Heart Failure Clinical Trials

Minimally Invasive Pericardiotomy as a New Treatment for Heart Failure

Start date: May 2019
Phase: N/A
Study type: Interventional

Researchers are studying the safety and efficacy of a minimally invasive treatment called a pericardiotomy, which creates a small opening in the sac that surrounds the heart. Researchers will test the short and long term effects of this procedure by monitoring subjects heart function and symptoms.

NCT ID: NCT03923413 Recruiting - Clinical trials for End Stage Heart Failure

Endothelial Function and Circulating Microparticle in Patients Under LVAD Support

MP-LVAD
Start date: May 1, 2017
Phase:
Study type: Observational

The aims of this project are 1) to evaluate whether circulating micraparticals (MPs) in patients with LVAD impair endothelial function and 2) to assess the procoagulative activity of circulating MPs in patients with LVAD in a prospective longitudinal study of patients undergoing LVAD implantation, 3) to analyze these parameters in the context of thromboembolic events.

NCT ID: NCT03919136 Recruiting - Heart Failure Clinical Trials

Wrist Worn Blood Pressure Measurement

Start date: August 1, 2018
Phase:
Study type: Observational

In this study, the investigators are testing the accuracy of a wrist-worn measurement device by comparing its blood pressure measurement to arterial line (A-line) blood pressure monitors. The device is similar in style and fit to popular activity bands, but it is unique in that it measures blood pressure.

NCT ID: NCT03917459 Not yet recruiting - Heart Failure Clinical Trials

COmparing arNi and Ace For Improving Erectile Dysfunction in mEN With reduCed Ejection Fraction Heart Failure

CONFIDENCE-HF
Start date: April 15, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the effect of LCZ696 vs. Enalapril on improvement in erectile function and ability in male patients with chronic heart failure with reduced ejection fraction and erectile dysfunction

NCT ID: NCT03914222 Not yet recruiting - Clinical trials for Congestive Heart Failure

Comparing PA Compliance During and After Decompensation in HFP

Start date: May 2019
Phase: N/A
Study type: Interventional

Pulmonary Artery Compliance measurements will be obtained with the Respirix device in patients with congestive heart failure decompensation. Echocardiogram, weight measurements, and BNP will also be gathered as independent measures of decompensation in the clinic. Pulmonary Artery Compliance measurements will be made daily during the hospital stay. Patients can continue using the device at home for the next 3 weeks. Each patient will serve as their own control and relative changes from their baseline will be recorded for each parameter.

NCT ID: NCT03913780 Completed - Heart Failure Clinical Trials

Impact of the Aerobic Exercise Versus Exercise of Force on the Hemodynamic, Lipidic, Anthropometric and Psychological Variables of Patients With Cardiac Failure

Start date: April 2016
Phase: N/A
Study type: Interventional

Introduction and objectives: At the global level, cardiovascular diseases are the leading cause of mortality. Currently, rehabilitation programs are shown as an effective treatment to mitigate the effects of heart failure. The main objective is to compare the effects of aerobic exercise and strength in patients with heart failure after a cardiovascular rehabilitation program. Methods and materials: Randomized controlled trial over a period of 3 years with patients with heart failure distributed in 3 groups (Aerobic exercise, aerobic exercise plus upper limb -MMSS- training, aerobic exercise plus training of lower limb -MMII-). Blood samples were taken to determine blood glucose levels and lipid profile. In addition, tests for aerobic capacity, maximum heart rate, anthropometry, depression, anxiety, clinical and hemodynamic parameters. The tests were performed before and after 24 training sessions, 60 min, 3 times a week for two months.

NCT ID: NCT03911349 Recruiting - Heart Failure Clinical Trials

Wrist Worn Blood Pressure Measurement

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

In this study, the investigators are testing the accuracy of a wrist-worn measurement device by comparing its blood pressure measurement to arterial line (A-line) blood pressure monitors. The device is similar in style and fit to popular activity bands, but it is unique in that it measures blood pressure.