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Stroke clinical trials

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NCT ID: NCT01126515 Completed - Stroke Clinical Trials

Functional and Anatomical Magnetic Resonance Imaging (MRI) of Chronic Brain Injury and Hyperbaric Oxygen (HBO2) Study Subjects

HYBOBI-MRI
Start date: July 2007
Phase:
Study type: Observational

The purpose of this study is to evaluate Brain MRI (Magnetic Resonance Imaging), and Brain CT (Computed Tomography) Angiogram data in subjects who participate in the "Hyperbaric Oxygen for Chronic Stable Brain Injury" (HYBOBI) study. Including information from MRI and CT studies provide information about whether hyperbaric oxygen improves brain function in subjects who have had a brain injury. Subjects will complete MR and CT scans twice during the study. The first MR and CT will be performed prior to the first hyperbaric session of the HYBOBI study, and the second will be performed within two weeks following the last hyperbaric session.

NCT ID: NCT01123382 Completed - Stroke Clinical Trials

Electrical Stimulation for Hemiplegic Shoulder Pain

Start date: January 2010
Phase: N/A
Study type: Interventional

Post-stroke shoulder pain is a major rehabilitation problem affecting moderate to severely impaired stroke survivors. Surface electrical stimulation (ES) of muscles surrounding the hemiparetic shoulder has been demonstrated to be beneficial, but despite the evidence for therapeutic benefit, the clinical implementation of surface ES for poststroke shoulder pain has been difficult. In order to address the limitations of surface ES, the investigative team pioneered the development of percutaneous intramuscular (IM) ES for the treatment of post-stroke shoulder pain. However, prior to acceptance by the clinical community, additional gaps in the scientific and clinical knowledge need to be addressed. This study begins to do so. The primary objective is to estimate the relative pain reduction associated with IM ES vs. "usual care." We hypothesize that the IM ES group will exhibit a larger effect size with respect to pain reduction compared to "usual care". A secondary objective is to estimate the effect on health related QOL of IM ES vs. "usual care." Demonstration of improvement in QOL will validate the clinical relevance of the intervention. We hypothesize that the IM ES group will exhibit greater improvement in health related QOL compared to "usual care".

NCT ID: NCT01123161 Terminated - Stroke, Acute Clinical Trials

The Intravascular Cooling in the Treatment of Stroke 2/3 Trial

ICTuS2/3
Start date: June 2010
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this trial is to determine whether the combination of thrombolysis and hypothermia is superior to thrombolysis alone for the treatment of acute ischemic stroke.

NCT ID: NCT01122394 Completed - Stroke Clinical Trials

Reducing Risk of Recurrence

RRR
Start date: January 2010
Phase: N/A
Study type: Interventional

Adults who have had a previous stroke or transient ischemic attack (TIA) remain at risk for having a second serious event, especially if they have uncontrolled blood pressure or cholesterol. However, many patients have difficulty following treatment recommendations for lowering blood pressure and cholesterol. The purpose of this research project is to evaluate the effect of 2 booster sessions of an educational counseling intervention on how well adults who have already participated in a 6-month clinical trial had a stroke or transient ischemic attack (TIA) are able to follow a treatment plan and control their blood pressure and cholesterol levels. We will also examine how effective this intervention is in improving adherence to diet, medication, and physical activity recommendations for adults who have had a prior stroke or TIA.

NCT ID: NCT01120301 Completed - Clinical trials for Acute Ischemic Stroke

Efficacy and Safety Trial of Transcranial Laser Therapy Within 24 Hours From Stroke Onset (NEST-3)

NEST-3
Start date: September 2010
Phase: Phase 3
Study type: Interventional

The purpose of this pivotal study is to demonstrate safety and efficacy of transcranial laser therapy (TLT) with the NeuroThera® Laser System in the treatment of subjects diagnosed with acute ischemic stroke. The initiation of the TLT procedure must be feasible for each subject between 4.5 and 24 hours of stroke onset.

NCT ID: NCT01117194 Recruiting - Stroke Clinical Trials

Effect on Shoulder Training Using Rehabilitation Robot for Stroke Patients

Start date: January 2010
Phase: Phase 1
Study type: Interventional

The purpose is to study the effect of rehabilitation robot on shoulder training for stroke patients.

NCT ID: NCT01116544 Completed - Stroke Clinical Trials

Treatment of Chronic Stroke With AMES + EMG Biofeedback

AMES
Start date: September 21, 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if individuals who had a stroke more than one year before entering the study and who remain unable to open their affected hand are better able to sense and move their affected arm after 10-15 weeks of treatment with a new robotic therapy device (the AMES device) and EMG biofeedback.

NCT ID: NCT01116466 Completed - Stroke Clinical Trials

Clinical Study to Evaluate the Implantation of the ActiGait Drop Foot Stimulator System

Start date: August 2009
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the efficacy and safety of surgical procedure involving ActiGait - implantable drop foot stimulator.

NCT ID: NCT01115660 Completed - Ischemic Stroke Clinical Trials

Stroke Education Intervention Trial - Pilot

AVAIL II
Start date: January 2010
Phase: N/A
Study type: Interventional

The objectives of the trial of a medication-coach program for patients with stroke or transient ischemic attack are to pilot test the study design, the intervention components and the data collection forms and refine them for a larger trial whose goal will be to improve long-term adherence to stroke prevention medications.

NCT ID: NCT01115348 Active, not recruiting - Stroke Clinical Trials

SALGOT; Stroke Arm Longitudinal Study at the University of GOThenburg

SALGOT
Start date: March 2009
Phase: N/A
Study type: Observational

Stroke is the most common cause for motor disability in the grown-up population in the Western world. In Sweden > 80 % are above 65 years of age at onset (1).Areas in the brain, controlling the movement in the upper extremity (UE) are often damaged at a stroke, which leads to impaired function. This impairment of the UE often leads to limitations in activities of daily living and reductions in the level of social activities; therefore, interventions that will improve function are needed to reduce the consequences for the person living with stroke. The time course of recovery of the UE is not clear and therefore the optimal timing of the intervention for the person and its content (ways of intervention) uncertain. The investigators have developed objective assessments of motor performance with new technology (kinematic analysis and virtual reality with haptics). Since having an impaired UE often results in reduced capacity in daily living and social activities, this might lead to decreased participation. To complement the traditional focus on body function, there is a need for assessments of the person's activity level and participation, as well as self-perceived function. The results from this study will lay the ground for an intervention study focusing on improved function in the upper extremity.