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Acute Ischemic Stroke clinical trials

View clinical trials related to Acute Ischemic Stroke.

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NCT ID: NCT03955835 Recruiting - Clinical trials for Acute Ischemic Stroke

Acandis Credo Intracranial Stent for Unsuccessful Recanalization After Thrombectomy (ACUTE)

ACUTE
Start date: May 2019
Phase: N/A
Study type: Interventional

Study objective is to evaluate the efficacy and safety of acute permanent stenting of symptomatic intracranial stenosis following unsuccessful recanalization by thrombectomy in acute ischemic stroke with large vessel occlusion using the self-expandable Credo® stent together with the NeuroSpeed® PTA balloon catheter.

NCT ID: NCT03927001 Recruiting - Clinical trials for Acute Ischemic Stroke

The Vesalio NeVa Stent Retriever Study for Treatment of Large Vessel Occlusion Strokes

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

A prospective, open label, single-arm 90-day study designed to assess the safety, performance and efficacy of thrombus removal in subjects presenting with acute ischemic stroke with the NeVa stent retrievers.

NCT ID: NCT03926988 Recruiting - Clinical trials for Acute Ischemic Stroke

The Vesalio NeVa Stent Retriever Registry Study for Treatment of Large Vessel Occlusion Strokes

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

A prospective, open label, 90-day study designed to assess the safety, performance and efficacy of thrombus removal in subjects presenting with acute ischemic stroke with the NeVa stent retrievers.

NCT ID: NCT03915834 Not yet recruiting - Clinical trials for Acute Ischemic Stroke

Biomarkers to Predict Hemorrhage and Outcomes After Endovascular Treatment in Patients With Acute Large Vessel Occlusion

Start date: April 16, 2019
Phase:
Study type: Observational [Patient Registry]

The main aim of the biomarkers to predict Hemorrhagic transformation(HT) after endovascular treatment in Acute Ischemic Stroke Patients. The study has three main parts. During the first part, the investigators propose to conduct an enrollment of patients after thrombectomy in acute Ischemic Stroke and healthy controls. Serum biomarkers levels were analyzed (before and after) endovascular treatment patients and controls respectively. During the second part, HT was evaluated and classified on cranial computed tomography and/or MRI post- treatment and was considered as symptomatic HT (sHT) if associated with neurological deterioration. During the third part, the investigators aim to demonstrate the level of biomarkers can significant predict HT and outcomes in stroke patients undergoing revascularization.

NCT ID: NCT03876457 Not yet recruiting - Clinical trials for Acute Ischemic Stroke

SELECT 2: A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

SELECT 2 evaluates the efficacy and safety of endovascular thrombectomy compared to medical management alone in acute ischemic stroke patients due to a large vessel occlusion in the distal ICA and MCA M1 who have large core on either CT (ASPECTS: 3-5) or advanced perfusion imaging ([rCBF<30%] on CTP or [ADC <620] on MRI: 50-100cc) or both and are treated within 0-24 hours from last known well.

NCT ID: NCT03868007 Not yet recruiting - Clinical trials for Acute Coronary Syndrome

Protective Effects of RIC in Elderly With Acute Ischemic Stroke Complicating Acute Coronary Syndrome

RIC-ACS
Start date: March 10, 2019
Phase: N/A
Study type: Interventional

Remote ischemic conditioning (RIC) is a noninvasive strategy in which one or more cycles of brief and transient limb ischemia confers protection against prolonged and severe ischemia in distant organs.This study aimed to investigate whether RIC is safe and effective in patients with AIS complicating ACS

NCT ID: NCT03844594 Not yet recruiting - Clinical trials for Acute Ischemic Stroke

Eptifibatide in Endovascular Treatment of Acute Ischemic Stroke (EPOCH)

Start date: April 1, 2019
Phase: Phase 3
Study type: Interventional

The study is a single-arm, open-label, multicenter clinical trial.The primary purpose of this trial is to evaluate the incidence of symptomatic intracranial hemorrhage in patients with acute ischemic stroke within 48 hours after the use of Eptifibatide injection. Patients with acute ischemic stroke treated with intravascular thrombolytic therapy, mechanical thrombolysis, angioplasty and so on were treated with Eptifibatide injection on the first day, followed by the second day, the third day, the discharge day and the 90 days.

NCT ID: NCT03825419 Recruiting - Clinical trials for Acute Ischemic Stroke

Detection of Muscle Loss in Acute Stroke Patients Who Need Enteral Nutrition (MASS)

MASS
Start date: January 23, 2019
Phase:
Study type: Observational

The degree of muscle loss over the course of inpatient stay will be evaluated in patients with a diagnosis of acute ischemic stroke admitted to Neurocritical Care Units and necessitating enteral nutrition.

NCT ID: NCT03824496 Recruiting - Clinical trials for Acute Ischemic Stroke

Head Pulse for Ischemic Stroke Detection

EPISODE
Start date: August 1, 2017
Phase:
Study type: Observational

Accurate diagnosis of stroke due to large vessel occlusion (LVO) is an essential step in providing acute stroke care to a community. The gold-standard for diagnosis LVO is brain imaging, which is impractical in the pre-hospital setting. A non-invasive method to detect LVO is needed. Using highly sensitive accelerometers, one can measure the "HeadPulse"- tiny forces exerted on the skull from the cardiac contraction. This study tests the hypothesis that LVO alters the HeadPulse characteristically. Analysis of these data along with the subjects vascular status (LVO vs. non-LVO as measured by CT angiography) will be used to create a model that can predict LVO status in suspect stroke subjects.

NCT ID: NCT03820882 Not yet recruiting - Clinical trials for Acute Ischemic Stroke

Stent Retriever for Thrombectomy Revascularisation of Large Vessel Occlusions in Acute Ischemic Stroke(Catfish)

Start date: February 10, 2019
Phase: N/A
Study type: Interventional

The study is a prospective, multi-center, stratified randomized, single-blind, parallel assignment, active control, non-inferiority trial. Patients are randomized 1 : 1 to either stent retriever(Catfish) or Solitaire for endovascular therapy for acute ischemic stroke. The study aims to evaluate the benefit and safety of stent retriever(Catfish) for acute ischemic stroke therapy, as compared to Solitaire FR.