Clinical Trials Logo

Ischemic Stroke clinical trials

View clinical trials related to Ischemic Stroke.

Filter by:

NCT ID: NCT03921827 Recruiting - Ischemic Stroke Clinical Trials

External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis

Start date: January 8, 2019
Phase: N/A
Study type: Interventional

Intracranial stenosis is prevalent among Asians and constitute a common cause of cerebral ischemia. While the best medical therapy carries stroke recurrence rates in access of 10% per year, intracranial stenting was associated with unacceptable peri-procedural ischemic events. Cerebral ischemic events are strongly related to the severity of intracranial stenosis, being high in patients with severe intracranial stenosis with poor vasodilatory reserve. Enhanced External Counter-Pulsation (EECP) therapy is known to improve myocardial perfusion by facilitating the development of collateral blood vessels in the heart. The investigators hypothesize that EECP therapy may be useful in patients with severe stenosis of intracranial internal carotid (ICA) or middle cerebral artery (MCA).

NCT ID: NCT03919370 Not yet recruiting - Ischemic Stroke Clinical Trials

Detection of Cerebral Ischemia With Artificial Intelligence.

TROT
Start date: May 8, 2019
Phase:
Study type: Observational

In patients undergoing planned surgery for carotid tromendarterendectomy, a non-invasive device that registers heart rate variability is attached. furthermore a non-invasive device that monitors cerebral oxygenation- near infrared spectroscopy is also attached. At times when surgeons clamps the carotid artery, there will be a moment with controlled cerebral ischemia. This will be registered by the devices. The information obtained will be used to teach artificial intelligence what patterns are related to cerebral ischemia. the same procedure will be performed in patients undergoing ocklusive cerebral trombectomy, so the artificial intelligence will learn to recognize cerebral reperfusion.

NCT ID: NCT03916133 Recruiting - Ischemic Stroke Clinical Trials

Analysis of Selective Cerebrovascular Distribution With FDCT in the Angiosuite

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the clinical feasibility of the angiographic Flat Detector CT perfusion imaging (6s PBV) technique. The investigators will examine the specific vessel distribution of patients with steno-occlusive disease, treated with a surgical extracranial-intracranial bypass and assess the cerebral perfusion during test occlusion upon a neurovascular treatment and in intracranial tumor patients referred for potential pre-operative embolization. This study encompasses three scientific objectives: 1. What is the selective contribution of an individual bypass artery to the brain perfusion? 2. Is a selective intra-arterial angiographic perfusion examination useful in the decision-making of performing pre-operative embolization of intracranial tumors? 3. What is the usefulness of performing additive 6s PBV images compared to classical 2D angiography and/or clinical neurological evaluation in case of test occlusion in the evaluation of possible mother vessel occlusion in treatment of complex neurovascular diseases?

NCT ID: NCT03915431 Not yet recruiting - Ischemic Stroke Clinical Trials

A Study of NCS-01 in Patients With Acute Ischemic Stroke

Start date: August 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This is an initial Phase1/2 dose-finding, double-blind, placebo-controlled, multi-center study to evaluate the safety and tolerability of NCS-01 in patients with acute ischemic stroke. All patients will be randomized within 24 hours of stroke onset. This study will be conducted in 2 stages.

NCT ID: NCT03910166 Not yet recruiting - Ischemic Stroke Clinical Trials

AcoArt VI / Vertebral Artery Ostium Stenosis in China

Start date: October 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether DEB is more effective than common PTA balloon using under in long-term vessel patency and inhibiting restenosis in Vertebral Artery Ostium Stenosis

NCT ID: NCT03906305 Active, not recruiting - Ischemic Stroke Clinical Trials

Dry Needling and Bobath Treatment Clinical Effects Focused on Stroke Patients

Start date: November 26, 2018
Phase: N/A
Study type: Interventional

The investigators aim to determine if dry needling technique in a non myofascial trigger point area generate the same spasticity, function and pain answers as carrying it out in a myofascial trigger point area. In the same way, the investigators aim to prove how much the effect lasts with an only intervention.

NCT ID: NCT03897478 Not yet recruiting - Stroke Clinical Trials

Biomarkers of Acute Stroke in Clinic

BASIC
Start date: April 1, 2019
Phase:
Study type: Observational

The proposed study will investigate the clinical use of the ISCDX test that may differentiate between diverse stroke etiologies as listed below: Aim 1: Differentiate between cardioembolic and large artery atherosclerotic ischemic strokes, when hemorrhagic stroke is ruled out, as defined by TOAST classification of subtypes of acute ischemic stroke. Aim 2: In cases of ischemic strokes of unknown or "cryptogenic" etiology, determine the ability of biomarker blood tests to predict etiology between cardioembolic and large artery atherosclerotic.

NCT ID: NCT03890380 Recruiting - Ischemic Stroke Clinical Trials

Safety and Performance Evaluation of the Magneto Wire

Start date: March 18, 2019
Phase: N/A
Study type: Interventional

A prospective, open label single arm feasibility study to evaluate the safety and performance of the Magneto Wire in patients diagnosed with acute ischemic stroke and planned for thrombectomy procedure.

NCT ID: NCT03884530 Not yet recruiting - Ischemic Stroke Clinical Trials

Ticagrelol Versus Aspirin in Ischemic Stroke

Start date: April 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

There is a debate whether ticagrelor is superior to aspirin in treating patients with ischemic stroke or not, most of the studies examine the effect of both drugs within 24 hours of acute stroke some find that there is no difference between ticagrelor and aspirin, others find that ticagrelor is superior to aspirin. At this study the investigators aim at evaluating the role of loading ticagrelor received within 9 hours of acute ischemic stroke in improving neurological outcome of stroke. And evaluating the risk of hemorrhagic and non- hemorrhagic complications associated with the use of ticagrelor180 ml oral loading dose within 9 hours acute ischemic stroke

NCT ID: NCT03874702 Enrolling by invitation - Stroke Clinical Trials

Automated Diagnosis of Stroke in Computed Tomography With the Use of Artificial Intelligence

Start date: June 1, 2019
Phase:
Study type: Observational [Patient Registry]

The use of the systems of machine learning for the quantification, location and diagnosis of ischemic stroke in non-contrasted head computed tomography, is a method with high efficacy, accessible and susceptible for standardization, for the assistance in the clinical decision making in the absence of specialized health personnel for the attention of this disease.