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Ischemic Stroke clinical trials

View clinical trials related to Ischemic Stroke.

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NCT ID: NCT03710902 Recruiting - Hypertension Clinical Trials

Empowerment and Mobile Technology in the Control of Cardiovascular Risk Factors in Patients With Ischemic Stroke

Start date: October 17, 2018
Phase: N/A
Study type: Interventional

The CARDIOSTROKE is a randomized trial comparing mobile-device assisted control of hypertension together with screening of occult atrial fibrillation to standard care in patients with recent ischemic stroke or transient ischemic attack.

NCT ID: NCT03685006 Recruiting - Inflammation Clinical Trials

Atherosclerosis and Acute Ischemic Stroke Study

Start date: January 1, 2009
Study type: Observational [Patient Registry]

A significant proportion of strokes are thromboembolic in nature, arising from atherosclerotic plaque at the carotid bifurcation. It is now wellknown that inflammation plays a key role in atherogenesis and plaque destabilization. However the identification and characterization of the different inflammatory factors, as well as their relative importance, have not been clarified. This main aim of this study is to identify new risk markers for atherosclerosis and to characterize more precise methods for detection of the unstable carotid plaque with increased stroke-risk.

NCT ID: NCT03673241 Not yet recruiting - Ischemic Stroke Clinical Trials

Study of the Guardian System on Motor Recovery and Impact on Length of Stay in Ischemic Stroke Patients

Start date: October 30, 2018
Phase: N/A
Study type: Interventional

This is a non-blinded randomized study that will investigate whether the use of a novel, non-invasive perfusion enhancement system (The Guardian System) impacts motor recovery and hospital length of stay in acute ischemic stroke patients.

NCT ID: NCT03668132 Completed - Ischemic Stroke Clinical Trials

Language Functional Reorganization in Subcortical Infarction Patients

Start date: January 19, 2016
Study type: Observational

Post stroke aphasia (PSA) is one of the most frequently happened deficiency of stoke, affecting speaking,comprehension, writing and reading of language. Generally, PSA is commonly seen in cortical damage, but in recent years it has been found that subcortical injury is also an important cause of PSA, which is called subcortical aphasia. Using fMRI technology, the investigators aim to investigate the language function of patients with subcortical cerebral infarction at different stages of recovery , and explored the mechanism of post-injury language reorganization in the brain. The investigators recruited 60 first-episode acute cerebral infarction patients with one-side lesion in subcortical white matter (40 with left injury and 20with right injury) and 20 health volunteers. All participants are right-handed, and screened with MMSE, HAMD and HAMA to exclude cases of psychosis, post-stroke dementia and depression. Each participant was arranged to have three test sessions at different stages after the infarction (T1:within 3 days after onset of the stroke ; T2:28 ±3days after onset; T3: 90±3days after onset), with fMRI and Western aphasia battery (WAB) in each session. The purpose of this study is to explore the pathogenesis of subcortical aphasia, and to understand the dynamic reorganization of language network during the recovery of language function.

NCT ID: NCT03653312 Recruiting - Ischemic Stroke Clinical Trials

Neuromuscular Electrical Stimulation in Acute Ischemic Stroke

Start date: August 27, 2018
Phase: N/A
Study type: Interventional

The purpose of the study is to examine the added effect of NeuroMuscular Electric Stimulation (NMES) as an exercise therapy tool in the acute phase of ischemic stroke in order to increase the patient's functionality. Further, to induce and measure neuroplasticity in the central nervous system during rehabilitation training. This randomized controlled trial includes 50 patients allocated to either control or intervention. The inclusion, test, training and re-test will be provided during the first 14 days after ictus, starting day 1 after ictus and a follow-up at day 90. The exercise training with external NMES is done with the patient every weekday for 27 minutes. The neural plasticity test will be performed using Transcranial Magnetic Stimulation (TMS).

NCT ID: NCT03629652 Recruiting - Ischemic Stroke Clinical Trials

Head-dOwn Position for ischEmic Stroke With Middle Cerebral Artery (HOPES)

Start date: August 6, 2018
Phase: N/A
Study type: Interventional

The study is designed to explore the efficacy and safety of head-down position in patients with acute ischemic stroke。

NCT ID: NCT03629275 Not yet recruiting - Ischemic Stroke Clinical Trials

Investigation of Neural Stem Cells in Ischemic Stroke

Start date: August 2018
Phase: Phase 2
Study type: Interventional

A study of stereotactic, intracerebral injection of CTX0E03 neural stem cells into patients with moderate to moderately severe disability as a result of an ischemic stroke.

NCT ID: NCT03608904 Recruiting - Ischemic Stroke Clinical Trials

Stroke Recovery and Music or No Music

Start date: July 21, 2017
Phase: N/A
Study type: Interventional

The primary outcome of this study is to determine the quantitative increase in connectivity, as measured by fMRI brain and calculated as a percent increase from baseline in patients with ischemic stroke. Eligible patients will receive a listening session of music or spoken word listening, 30 days to 5 years following ischemic stroke. Assessments will include modified Rankin Scale, National Institute of Health Stroke Scale, functional Magnetic Resonance Imaging, motor function tests, and neuropsychological evaluations. Assessments occur at baseline, day 45, and day 90 after starting listening sessions.

NCT ID: NCT03602326 Completed - Ischemic Stroke Clinical Trials

Neurodevelopmental Therapy-Bobath Approach in The Early Term of Stroke; Safe and Effective

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Early term rehabilitation initiated after stroke should be based on motor learning principles and neural plasticity. To achieve motor learning and neural plasticity, exercises consisting of intense and repetitive training should be given according to the patients' functional level. The neurodevelopmental treatment-Bobath (NDT_B) approach is based on motor learning principles. In literature, studies that show the early term effects of NDT-B on functional recovery are inadequate. The aim of this study was to investigate the effects NDT-B applied in the early term of stroke, on postural control, functional movement, balance and activities of daily living.

NCT ID: NCT03596502 Active, not recruiting - Atrial Fibrillation Clinical Trials

Direct Oral Anticoagulants in Patients With Atrial Fibrillation (DOACs vs Warfarin)

Start date: February 1, 2018
Study type: Observational

The purpose of this study is to assess safety and effectiveness of direct oral anticoagulants (DOACs) and warfarin for stroke prevention in patients with non-valvular atrial fibrillation (AF). The comparison of DOACs versus oral vitamin K antagonists, in particular warfarin, is of interest. The investigators will carry out separate population-based, matched cohort studies, using health administrative databases in seven Canadian provinces. New users of oral anticoagulants (DOACs or warfarin) for stroke prevention in non-valvular AF will be eligible to enter the cohorts. Follow-up will continue until a hospitalization or emergency department visit for a stroke. The results from the separate sites will be combined by meta-analysis to provide an overall assessment of the safety and effectiveness of the different anticoagulation regimens in stroke prevention in AF. We hypothesize that DOACs and warfarin will have similar safety and effectiveness profiles.