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Stroke clinical trials

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NCT ID: NCT06196229 Recruiting - Stroke Clinical Trials

Effects of Action Observation Therapy Based on Virtual Reality for Upper Extremity Rehabilitation in Stroke

Start date: November 25, 2023
Phase: N/A
Study type: Interventional

This study aims to conduct a randomized controlled trial (RCT) assessing the effectiveness of combining Action Observation (AO) with Virtual Reality (VR) in improving upper limb function for stroke patients compared to AO therapy alone. Individuals who meet the inclusion criteria will be assigned by lottery into one of two groups: Group A will receive only AO therapy, watching daily actions and then executing them, while Group B will receive both AO and VR therapy, using VR glasses to complete tasks. The Box and Block Test for manual dexterity, the Timed Test, the Modified Ashworth Scale for spasticity, the Rankin Scale for symptom severity, and the Fugl-Meyer Assessment for motor, balance, sensation, and joint function will all be used in the evaluation, both before and after the intervention. Every participant will go through 18 sessions totaling 60

NCT ID: NCT06196047 Recruiting - Ischemic Stroke Clinical Trials

Ticagrelor Versus Cilostazol in Minor Ischemic Stroke or TIA

Start date: December 1, 2021
Phase: Phase 3
Study type: Interventional

Along with the current clinical trial, the efficacy and safety of ticagrelor and aspirin administered within the first 24 hours of first-ever ischemic stroke compared to cilostazol and aspirin were assessed through NIHSS, mRS, and possible adverse effects.

NCT ID: NCT06195969 Recruiting - Stroke Clinical Trials

Instant Message-guided Hypertension Management Intervention Among Stroke Survivors

Start date: November 13, 2023
Phase: N/A
Study type: Interventional

This pilot and feasibility study aims to develop an automated instant message-delivered intervention (i.e., EMI) for hypertension management in stroke survivors, and to investigate the feasibility and effectiveness of the intervention.

NCT ID: NCT06195501 Recruiting - Clinical trials for Ischemic Stroke, Acute

Dysphagia After Transesophageal Echocardiography in Acute Stroke - Follow Up Trial

TEDRAS2
Start date: May 1, 2023
Phase:
Study type: Observational [Patient Registry]

The aim of the prospective observational TEDRAS - Follow-up Trial is to investigate the limitations of the initial TEDRAS - Trial in patients with acute Dysphagia is a common consequence from ischemic stroke and it correlates with an increased risk of pulmonary complications such as aspiration pneumonia and an increased mortality risk. TEDRAS-Trial (Transesophageal Echocardiography: Dysphagia Risk in the Acute Phase After Stroke; ClinTrial.gov identifier NCT04302883) was the first randomized and controlled trial to address the question of the extent to which TEE increases dysphagia risk in acute stroke patients. The results of the study confirmed the hypothesis that dysphagia severity worsens after TEE in the intervention group. The aim of the prospective observational TEDRAS - Follow-up Trial is to investigate the limitations of the initial TEDRAS - Trial in patients with acute ischemic stroke.

NCT ID: NCT06195007 Recruiting - Acute Stroke Clinical Trials

Motivational Interviewing for Stroke

Start date: August 1, 2024
Phase: N/A
Study type: Interventional

Motivational interviewing (MI) is a style of communication designed to elicit a person's own reasons for change to drive commitment toward a goal. The goal of this study is to assess the effect of trainee-led MI on patients diagnosed with acute stroke or TIA attributable to modifiable risk factors in comparison to conventional post-stroke counseling, based on patient outcomes, and meaning of work and sense of fulfillment for trainees.

NCT ID: NCT06194968 Recruiting - Clinical trials for Acute Ischemic Stroke

Treatment of Acute Ischemic StroKe With Intravenous UroKinase Real-world Research: a Multicenter, Prospective Study

Start date: December 30, 2023
Phase:
Study type: Observational

The purpose of this study is to to compare the safety and effectiveness of IV urokinase with IV alteplase in the treatment of AIS in patients up to 6 hours from symptom onset.

NCT ID: NCT06192953 Recruiting - Stroke (CVA) or TIA Clinical Trials

Early Functional Proprioceptive Stimulation Post-stroke

StimProF
Start date: May 6, 2024
Phase: N/A
Study type: Interventional

The main objective of our study is to evaluate the impact of the use of Functional Proprioceptive Stimulation (FPS) on the recovery of the postural and motor functional capacities of the patient in the subacute phase of a stroke. The hypothesis is that the use of FPS has a positive impact on the recovery of the patient's functional abilities, as well as on the duration of treatment until the sit/stand transfers are completed. To evaluate this potential effect,there will be a randomization with two groups : one will have 5 sessions a week for 6 weeks maximum of SPF and the other groupe will have the same sessions but with the device stettled but not activated.

NCT ID: NCT06192485 Enrolling by invitation - Stroke Clinical Trials

Proactive and Reactive Balance Training Effects on Balance and Functional Performance Among Chronic Stroke Survivors

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The study is an RCT study, comparing the proactive and reactive balance training among stroke survivors, the participants will be chronic stroke patients aged between 50- 75 years old, and the participants will receive a balance training program for 8 weeks 3 sessions in the week, the participants will randomly be allocated in two groups proactive group and the reactive group, at the end of the study will compare the different effects between proactive and reactive balance training

NCT ID: NCT06192342 Recruiting - Stroke Clinical Trials

Ventilatory Parameters in Acute Neurological Injury

Start date: May 1, 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to test the association between baseline ventilatory parameters (in particular mechanical power (MP), mechanical power normalized to predicted body weight (MP/PBW) and driving pressure (DP) with the baseline neurological status (assessed through the Glasgow coma score) in adults patients under mechanical ventilation with acute neurological injury secondary to stroke, brain trauma or subarachnoid hemorrhage. The main question[s]it aims to answer are: 1. In patients with acute neurological injury under mechanical ventilation, is there a correlation between the acute neurological injury, assessed using the Glasgow scale on admission, and baseline ventilatory parameters? 2. In patients with acute neurological injury under mechanical ventilation, are the baseline ventilatory parameters altered at baseline?

NCT ID: NCT06191549 Not yet recruiting - Clinical trials for Cerebral Vascular Accident

Brain Stimulation Enhance Post-stroke Walking Survivors and Healthy Adults

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

Recent studies showed that a non-invasive, low-intensity brain stimulation called transcranial direct current stimulation (tDCS) can effectively increase motor neuron excitability in the brain and therefore promotes functional recovery after stroke. Thus, the overall purpose of this research project is to examine the effect of brain stimulation on motor skill learning in stroke survivors.