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Acute Stroke clinical trials

View clinical trials related to Acute Stroke.

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NCT ID: NCT03635749 Not yet recruiting - Clinical trials for Transient Ischemic Attack

Intensive Medical Therapy for High-risk Intracranial or Extracranial Arterial Stenosis

INSPIRES
Start date: August 30, 2018
Phase: Phase 3
Study type: Interventional

Large-artery stenosis plays an important role in the occurrence of ischemic stroke. The primary purpose of this study is to evaluate the efficacy and safety of intensive antiplatelet therapy versus standard antiplatelet therapy and early intensive statin therapy (80mg atorvastatin) versus delayed intensive statin therapy (40mg atorvastatin) and intensive antiplatelet combined with early intensive statin therapy (80mg atorvastatin) versus standard antiplatelet combined with delayed intensive statin therapy (40mg atorvastatin) in reducing the risk of stroke at 90 days in patients with acute and high-risk symptomatic extracranial or intracranial arterial stenosis.

NCT ID: NCT03622515 Not yet recruiting - Clinical trials for Transient Ischemic Attack

the Research of the Cerebral Protection Effects of Electroencephalogram (SedLine) During Carotid Endarterectomy

Start date: July 30, 2018
Phase: N/A
Study type: Interventional

Fragile brain is the most common phenomenon seen in the patients undergoing CEA. The patients with fragile brain have a high incidence of postoperative brain dysfunction. This study intends to apply EEG monitoring (Sedline) to CEA to investigate whether EEG monitoring can reduce the incidence of postoperative neurological complications in CEA patients and improve their prognosis. 220 patients with CEA were randomly divided into 2 groups. Group S [Sedline monitoring + Transcranial Doppler (TCD) + regional cerebral oxygen saturation (rS02),n=110] and group C [Bispectral index (BIS) + TCD +rSO2,n=110], recording intraoperative and postoperative conditions, neuropsychology scale assessment, blood examination and imaging examination. The incidence of postoperative neurological complications was compared between the two groups.

NCT ID: NCT03621917 Recruiting - Acute Stroke Clinical Trials

Evaluation of tPA Efficacy in Acute Stroke Patients With NIRS (Near-infrared Spectroscopy)

E-NESE
Start date: November 1, 2017
Phase:
Study type: Observational

Investigators aim to study efficiency of systemic thrombolytic therapy on acute ischemic stroke patients with near infrared spectroscopy.

NCT ID: NCT03571529 Recruiting - Acute Stroke Clinical Trials

Robotic Rehabilitation in Patients With Acute Stroke

Start date: April 6, 2018
Phase: N/A
Study type: Interventional

The advantage of the EMG-driven exoskeletons is that patient's own muscle power known as Residual Muscle Power is used to move the extremity while many other robotic devices work and drive impaired limb based on machine directed force. However, it is not clear which group of patients are suitable for EMG driven exoskeletons use and there has not been any established treatment protocol. The aims of the study are 1- to investigate the effectiveness of the EMG-driven exoskeleton for hand rehabilitation in patients with acute stroke. 2- to understand which group of the patients may give the best response to the EMG-driven technology and how should be the treatment protocol designed.

NCT ID: NCT03510312 Recruiting - Acute Stroke Clinical Trials

Long-term Prognosis in Stroke Patients

Start date: December 2011
Phase:
Study type: Observational [Patient Registry]

A single-center cohort of patients with acute ischemic stroke and transient ischemic attack who admitted to the Severance hospital of Yonsei university and their long-term outcomes.

NCT ID: NCT03481205 Not yet recruiting - Acute Stroke Clinical Trials

Ischemic Conditioning by Aircrews for Refractory Occlusions

ICARO
Start date: June 1, 2018
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to demonstrate the feasibility of performing remote limb ischemic conditioning (RLIC) using the Doctormate device, a special blood pressure device used to perform RLIC, on patients with acute ischemic stroke due to large vessel occlusion being transported to a thrombectomy capable center by the helicopter.

NCT ID: NCT03477188 Completed - Exercise Clinical Trials

The Effects of Somatosensory and Vestibular Rehabilitation Additional Conventional Therapy on Balance in Patients With Acute Stroke.

Start date: September 30, 2017
Phase: N/A
Study type: Interventional

This study was planned to evaluate the effects of somatosensory and vestibular rehabilitation additional conventional therapy on balance in patients with acute stroke.

NCT ID: NCT03472625 Recruiting - Acute Stroke Clinical Trials

The Incidence of Aphasia, Dysarthria and Dysphagia Following Stroke

Start date: March 14, 2018
Phase:
Study type: Observational

The objective of the study is to estimate the incidence and recovery of aphasia, dysarthria and dysphagia in an acute setting (first week) with the NIHSS sub-item scores for language and speech and a dysphagia screening. Furthermore, we will evaluate the severity of aphasia, dysarthria and dysphagia in an acute setting (first few days) with standardized measurements (ScreeLing, BNT, NSVO-Z, perceptual assessment, MASA/FOIS). To evaluate the effect of early IVT/EVT in patients with ischemic stroke on functional outcomes for language and speech via the NIHSS scale.

NCT ID: NCT03451903 Completed - Acute Stroke Clinical Trials

Which Factors Influence the Duration and the Success of Mechanical Thrombectomy During the Acute Phase of Cerebral Infarction?

REPAIR-FC
Start date: January 1, 2015
Phase:
Study type: Observational

This study aims to identify factors influencing the time span and success of reperfusion after a mechanical thrombectomy in the acute phase of cerebral infarction, and in particular the effect of intra-venous thrombolysis.

NCT ID: NCT03443596 Recruiting - Blood Pressure Clinical Trials

Blood Pressure Control in Acute Ischemic Stroke

BP-Stroke
Start date: December 2014
Phase: Phase 2/Phase 3
Study type: Interventional

Management of acutely elevated blood pressure during the early phase of ischemic stroke remains controversial. In patients treated with IV-tPA, the risk of ICH is closely related to the BP levels. However, intensive reduction of BP carries a theoretical risk of clinical deterioration by inducing cerebral hypoperfusion. Assessment of cerebral perfusion before and after BP reduction is one of the most scientific method to evaluate the safety (and potential benefits) of BP management in the acute phase of stroke. This project will impact practices and delivery of BP management during the acute phase of ischemic stroke. The findings would aid in designing phase 3 clinical trials will track clinical indicators, including the impact on functional outcomes as well as quality-of-life and cost-effectiveness.