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Stroke clinical trials

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NCT ID: NCT03625804 Completed - Stroke Clinical Trials

The Cortical Motor Effects of PNS and AO on Motor Training in Chronic Stroke

Start date: June 23, 2014
Phase: N/A
Study type: Interventional

This study aimed to investigate if peripheral nerve stimulation (PNS) paired with action observation (AO) would augment motor training in promoting corticomotor excitability for the paretic hand in people with stroke. Twenty subjects in chronic stage of stroke were exposed to 3 different interventions involving one-hour PNS or sham PNS paired with 30 minutes of AO or sham AO, all followed by 30 minutes of finger abduction training in 3 separate sessions.

NCT ID: NCT03623841 Recruiting - Stroke Clinical Trials

Training With Exergame and Treadmill on Executive Function and Dual-task Performance

Start date: November 9, 2018
Phase: N/A
Study type: Interventional

This study aimed to investigate the effects of dual-task training with exergame and treadmill on executive function and dual-task performance in individuals with PD and stroke and discuss the correlation between the change values of executive function and dual-task performance after training. Besides, investigate cortical activation after training.

NCT ID: NCT03622879 Recruiting - Stroke Clinical Trials

Mirror Therapy With Cutaneous Electrical Sensory Stimulation on Lower Limb Motor Functions in Stroke

Start date: July 2, 2018
Phase: N/A
Study type: Interventional

This study aims to evaluate the effectiveness of concurrent mirror therapy (MT) and transcutaneous electrical nerve stimulation (TENS) in augmenting the efficacy of the lower limb task-oriented training in people with stroke. It is hypothesize that MT combined with TENS would be superior to sham-mirror therapy with TENS, or MT with placebo-TENS, or control training only in improving lower limb motor functions and walking ability in people with stroke when combined with the lower limb task-oriented training.

NCT ID: NCT03622606 Active, not recruiting - Stroke Clinical Trials

Development and Validation of a Language Screening Test in Acute Right Hemispheric Strokes

R-LAST
Start date: September 25, 2018
Phase: N/A
Study type: Interventional

This is a bi-centric study whose main objective is the validation of a rapid screening test for language disorders in the acute phase of right hemisphere stroke. Primary objective The main objective is the validation of a rapid language disorder screening tool that will be used in the acute phase of right hemispheric stroke. Secondary objectives Secondary objectives are: - Characterize the "atypical crossed aphasia" since the acute phase of stroke with a large cohort of patients , which, to our knowledge, has never been done. - Re-evaluate the number of patients with acute language disorder in right hemisphere stroke. - Validate the use of R-LAST by different categories of carers

NCT ID: NCT03622515 Recruiting - Clinical trials for Postoperative Delirium

the Research of the Cerebral Protection Effects of Electroencephalogram (SedLine) During Carotid Endarterectomy

Start date: August 10, 2018
Phase: N/A
Study type: Interventional

Fragile brain is the most common phenomenon seen in the patients undergoing CEA. The patients with fragile brain have a high incidence of postoperative brain dysfunction. This study intends to apply EEG monitoring (Sedline) to CEA to investigate whether EEG monitoring can reduce the incidence of postoperative neurological complications in CEA patients and improve their prognosis. 220 patients with CEA were randomly divided into 2 groups. Group S [Sedline monitoring + Transcranial Doppler (TCD) + regional cerebral oxygen saturation (rS02),n=110] and group C [Bispectral index (BIS)/Sedline monitoring + TCD +rSO2,n=110], recording intraoperative and postoperative conditions, neuropsychology scale assessment, blood examination and imaging examination. The incidence of postoperative neurological complications was compared between the two groups.

NCT ID: NCT03622411 Completed - Stroke Clinical Trials

Tablet-based Aphasia Therapy in the Chronic Phase

Start date: September 7, 2018
Phase: N/A
Study type: Interventional

Aphasia is one of the most common and disabling disorders following stroke, in many cases resolving in long-term deficits. There is evidence that intensive aphasia therapy is effective for language recovery, even in the chronic phase post-stroke. However, as many patients are left with residual language disorders and intensive aphasia rehabilitation is difficult to achieve, the investigators are exploring tablet-based therapies to further facilitate language recovery in a cost-effective manner.

NCT ID: NCT03621917 Completed - Stroke, Ischemic Clinical Trials

Evaluation of the Effectiveness of Thrombolytic Therapy in Acute Ischemic Stroke Patients Using NIRS

E-NESE
Start date: November 1, 2017
Phase:
Study type: Observational

Investigators aim to study effectiveness of systemic thrombolytic therapy on acute ischemic stroke patients with near infrared spectroscopy.

NCT ID: NCT03621826 Completed - Sickle Cell Disease Clinical Trials

Evaluating Barriers to Stroke Screening and Prevention in Children With Sickle Cell Disease

DISPLACE
Start date: February 12, 2018
Phase:
Study type: Observational

DISPLACE is a three part, multi-center U.S. based study to evaluate the barriers to stroke screening and prevention in children with sickle cell anemia (SCA). In the United States, TCD (Transcranial Doppler ultrasound) is a proven method of screening children with SCA for stroke. However, many children are not getting the screening they need. This study will examine the issues that hinder and help children get the screening at 28 different hospitals and sickle cell centers to improve care for all children with sickle cell anemia. The investigators will then plan a study (part 3) aimed to improve stroke screening and prevention in sickle cell anemia.

NCT ID: NCT03620370 Completed - Stroke, Acute Clinical Trials

Normobaric Hyperoxia Combined With Reperfusion for Acute Ischemic Stroke

Start date: August 12, 2018
Phase: N/A
Study type: Interventional

NBO is a nonpharmacological measure of neuroprotection. The purpose of our study is to evaluate the safety and efficiency of NBO(Normobaric hyperoxia) in the acute ischemic stroke patients who received endovascular treatment. Looking for more clinical evidence for the ischemic stroke patients who will be treated with NBO in the future.

NCT ID: NCT03619772 Active, not recruiting - Stroke Clinical Trials

EMG Training for Altering Activation Patterns After Stroke

Start date: June 28, 2018
Phase: N/A
Study type: Interventional

Evaluation of a new EMG controlled game to improve hand function in chronic stroke survivors.