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Stroke clinical trials

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NCT ID: NCT03795948 Active, not recruiting - Stroke Clinical Trials

Patient Reported Outcomes in Stroke Care

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

The presented study is an explorative prospective study. First, it focusses on the longitudinal analysis of outcome quality in stroke treatment (12 months). Particularly, it addresses patient reported quality of life after inpatient stroke treatment and influencing factors. Second, it focusses on the feasibility and acceptance of a standard set of measures capturing outcome quality of medical care in stroke patients.

NCT ID: NCT03794947 Not yet recruiting - Fatigue Clinical Trials

Remote Ischaemic Conditioning for Fatigue After Stroke

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This is a pilot randomised control trial to assess the safety, compliance, and acceptability of delivering a 6-week programme of remote ischaemic conditioning (RIC) to stroke patients suffering with fatigue, and study feasibility. A minimum of 34 patients who have suffered an ischeamic or haemorrhagic stroke and who suffer from fatigue, will be recruited and randomised to receive a 6-week programme of either RIC or a sham intervention.

NCT ID: NCT03792126 Not yet recruiting - Stroke Clinical Trials

Implicit Learning in Stroke Study

Start date: February 2019
Phase: Phase 2
Study type: Interventional

This trial will compare an Implicit Learning Approach (ILA) to usual care, during the rehabilitation of mobility post stroke. It is a multicentre, assessor blind, cluster randomised controlled pilot trial, with embedded feasibility study. It also includes a nested qualitative evaluation, designed to explore the views of participants and therapists.

NCT ID: NCT03792061 Not yet recruiting - Stroke Clinical Trials

Enhancing Community Participation for Stroke Survivors With Cognitive Impairments

Start date: January 14, 2019
Phase: N/A
Study type: Interventional

Abstract Method: Participants with a diagnosis of stroke will be randomly assigned to the intervention group and the attention control group at a 1:1 ratio. Participants received 2 sessions per week for 12 to 15 sessions. Outcome measures including the Participation Measure- 3 Domains, 4 Dimensions (PM-3D4D), Canadian Occupational Performance Measure(COPM), Activity Measure for Post-Acute Care (AMPAC) Outpatient Short Forms, Wisconsin Card Sorting Task (WCST), and Participation Strategies Self Efficacy Scale (PS-SES) will be administered at baseline (T1), post-intervention (T2), 3-month follow-up (T3), 6-month follow-up (T4), and 12-month follow-up (T5).

NCT ID: NCT03791671 Not yet recruiting - Stroke Clinical Trials

Balance Training After Stroke - a Randomized, Controled Pilot Study

Start date: January 7, 2019
Phase: N/A
Study type: Interventional

This pilot study is part of a master's thesis. In the rehabilitation of stroke patients should be compared whether individual balance training has a greater effect than group balance training. The result is determined based on the walking speed.

NCT ID: NCT03790800 Not yet recruiting - Stroke, Acute Clinical Trials

Intensive Ambulance-delivered Blood Pressure Reduction in Hyper-Acute Stroke Trial

Start date: May 1, 2019
Phase: Phase 3
Study type: Interventional

A multicentre, ambulance-delivered, prospective, randomized, open-label, blinded endpoint (PROBE) study to assess the effects of pre-hospital blood pressure (BP) lowering initiated in ambulance setting on (i) hematoma volume at 24 hours in patients with confirmed intracerebral haemorrhage (ICH), and (ii) safety in patients with confirmed acute ischaemic stroke and other conditions that were initially suspected as acute stroke (i.e. stroke mimic)

NCT ID: NCT03789994 Not yet recruiting - Clinical trials for Post-stroke Depression

Affective Touching on Poststroke Depression

Start date: January 15, 2019
Phase: N/A
Study type: Interventional

This mixed-method study includes a randomised controlled trial and an exploratory qualitative study, and aims to examine the effects of caregiver-delivered affective touch on depressive symptoms, state of attachment security, self-esteem, and perceived family harmony among stroke survivors, and to explore the mediating effect of attachment security and how an intervention may affect depressive symptoms from stroke survivor's perspective. A total of 184 survivor-caregiver dyads will be recruited from various non-governmental organisations. The dyads will be randomly allocated to intervention (IG) and control (CG) groups, stratified by the survivor's attachment style. IG caregivers will be taught to deliver a 15-minute affective touch intervention to stroke survivors. To address the attention effect, CG caregivers will be asked to sit with the survivors during a 15-minute fine motor coordination exercise. Both activities, affective touching and fine motor exercise, will be performed for 12 weeks (3 times/week), and the outcomes mentioned earlier will be measured at baseline, 12 and 36 weeks after study entry.

NCT ID: NCT03789409 Not yet recruiting - Ischemic Stroke Clinical Trials

Intermittent Fasting Following Acute Ischemic Stroke

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Despite numerous kinds of evidence on functional health and CNS protection of intermittent fasting after injuries were found in many brain-, and spinal cord-damaged animal models, there has yet to be any clinical study of intermittent fasting after acute ischemic cerebral infarction. The aim of this study is to evaluate the neurological, functional and clinical efficacy of intermittent fasting in patients after acute ischemic stroke.

NCT ID: NCT03789357 Recruiting - Stroke Clinical Trials

Prevalence of Primary Aldosteronism in Patients With Stroke

Start date: May 1, 2018
Study type: Observational

Strokes leads to significant morbidity and mortality, and hypertension is the most important risk factor for strokes. It is estimated that up to 10% of patients with hypertension have the underlying, treatable condition of primary aldosteronism. Hence, we hypothesize that the prevalence of primary aldosteronism is high in patients with strokes, a complication of long-standing hypertension. Patients admitted with an acute stroke to the Acute Stroke Unit, Changi General Hospital, will be screened for Primary Aldosteronism three months post-stroke, and confirmatory tests will be done with saline-infusion test.

NCT ID: NCT03787693 Recruiting - Stroke Clinical Trials

Virtual Reality Augmented Gait Adaptation in Stroke Survivors

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

The major problem in stroke survivors that is being addressed in this research project is walking asymmetry, i.e., difference between the legs during walking (e.g. steps on the more affected side are longer than the other). A potential solution to this problem is using new technology like virtual reality during walking training to make stroke survivors have a better sense of their asymmetry. A second problem that we aim to address in this study is whether asymmetry is accurately felt by the stroke survivors and how we can address it. Our ongoing work on the effects of virtual reality on learning new walking tasks in stroke survivors indicates that virtual reality maybe particularly important for those with walking asymmetry. In this study, we plan to recruit stroke survivors who have such asymmetries during walking and have them learn a new walking task in virtual reality. We will also test the stroke survivors to determine if there is a relationship between how well they learn the new task with their ability to feel asymmetry accurately.