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Stroke clinical trials

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NCT ID: NCT03580642 Recruiting - Stroke Clinical Trials

Decision Support System for Stroke Survivors

Start date: April 27, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the usability of the system and its accordance with the users' needs. This evaluation will consider the effectiveness and the efficiency of the system, as well as stroke survivors' satisfaction. The effectiveness and the efficiency of the system will be measured by: - The relationship between the control of stroke survivors' daily activities and their risk of having a secondary stroke, - The decrease of the need for caregivers, - And consequently an improvement in stroke survivors' self-management.

NCT ID: NCT03579992 Active, not recruiting - Stroke Clinical Trials

Myoelectric Computer Interface to Reduce Muscle Co-activation After Stroke

Start date: July 2014
Phase: N/A
Study type: Interventional

This study examines whether in-lab training with a myoelectric-computer interface (MyCI) can reduce abnormal muscle co-activation after stroke.

NCT ID: NCT03578822 Not yet recruiting - Clinical trials for Acute Ischaemic Stroke

Thrombolysis With rhPro-UK in 4.5-6 Hours After Acute Ischemic Stroke in a Double-blinded,Controlled Trial

Start date: July 2018
Phase: Phase 3
Study type: Interventional

This is a randomized,controlled, double-blinded, phase 3 clinical study to evaluate the efficacy and safety of recombinant human urokinase(rhPro-UK) versus basic treatment for patients with acute ischaemic stroke in 4.5-6 hours after stroke onset.

NCT ID: NCT03578536 Not yet recruiting - Stroke Clinical Trials

Effect of Constraint-Induced Gaming Therapy in an Acute Care Setting

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Current protocols for therapy on a rehabilitation unit call for intensive rehabilitation composed of high intensity, long duration therapy. Evidence from brain healing and animal research, along with motor learning principles suggest that a treatment program composed of short duration therapy sessions distributed throughout the day may provide better rehabilitation outcomes for stroke patients. Such a program can be implemented using constraint-induced therapy in which the Veteran is provided with opportunities to use the affected limb while participating in a video game and completing complementary tasks in therapy. Additionally, rehabilitation outcomes may improve if Veterans are provided with regular opportunities to participate in gaming therapy at home after discharge from the hospital rather than having to travel to a clinic or receive limited or no follow-up in rural areas. This project will develop a therapeutic model that promotes use of the impaired arm and hand. Researchers often call this type of therapy "constraint induced therapy". In this study, participants focus on using the impaired limb rather than the unaffected limb. Study participants will only be able to play the game using the impaired limb. A small group of patients will participate in a question and answer session about preferences for activities which make up transfer tasks. Patients will also receive automated reminders to use the impaired arm throughout the day. Twelve (12) Veterans will be recruited annually from the inpatient Stroke Specialty Program. Six (6) patients will be assigned to the Treatment group and receive the intervention. The remaining six (6) will receive the current standard of care. Outcome measures will include motor function tests that evaluate upper extremity function.

NCT ID: NCT03578250 Recruiting - Stroke Clinical Trials

Error Augmentation Training Post Stroke

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Post-stroke individuals continue to suffer from significant motor impairments years after the stroke. Motor recovery is usually limited to the first 6 month after the stroke, in which the majority of improvements occur at the first three months. Error augmentation (EA) training using a robotic apparatus was suggested to enhance motor recovery by exploiting the adaptation mechanisms within the intact cerebellum in individuals who sustained cortical stroke. The aim of this study is to investigate whether error augmentation training for the upper extremity may enhance motor recovery in individuals that sustained cortical stroke. Fifty post-stroke individuals will be randomaly assigned into either EA training (study group- SG) or robotic training in null field environment (control group- CG). Both groups will carry out the same treatment protocol on the robotic device in addition to the standard rehabilitation protocol of the rehabilitation center. Treatment protocol will be consisted of about six training sessions on the robotic device, taken twice or three times a week for two to three weeks. Each training session will be composed of 20-30 minutes upper extremity training with or without EA force field. Motor performance will be evaluated before and after the treatment protocol by the Fugl-Meyer Assessment scale.

NCT ID: NCT03578107 Not yet recruiting - Ischemic Stroke Clinical Trials

Improve Acute Reperfusion Treatment Quality for Stroke in China, IMPROVE: Stroke Care in China

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

In order to bridge the great gaps, Chinese Stroke Association (CSA) and American Heart Association (AHA) sought to develop, conduct, and assess a multifaceted quality improvement intervention to increase the adherent rate of IV tPA and ET and improve 3-month clinical outcomes for these patients through our cluster-randomized stepped-wedge IMPROVE: Stroke in China trial.

NCT ID: NCT03577847 Recruiting - Stroke Clinical Trials

Rural CT Examination and Thrombolytic Treatment for Stroke

Start date: November 20, 2017
Study type: Observational [Patient Registry]

To counteract long term sequelae from stroke you need ultrarapid diagnosis and treatment, high quality multidiciplinary in-hospital care and optimal long term rehabilitation. In this study, the investigators are moving the essential first diagnosis and treatment out into the community close to where the patient lives thus shortening the all important time from debut of symptoms to thrombolytic treatment improving the prognosis of stroke patients.

NCT ID: NCT03577444 Not yet recruiting - Stroke Clinical Trials

Role of Genetic Polymorphism in Neuroplasticity Involved in Dysphagia Recovery

Start date: July 1, 2018
Study type: Observational

The purpose of this study is to assess the association of genetic polymorphism such as the Brain-derived Neurotrophic factor (BDNF), in neurogenic dysphagia in those with brain lesion.

NCT ID: NCT03577353 Completed - Stroke Clinical Trials

Dual-task Training Using Virtual Reality

Start date: October 30, 2013
Phase: N/A
Study type: Interventional

The purpose of the study was to investigate the feasibility of using a virtual reality- based dual task training of upper extremity tracking while treadmill-walking, to improve walking and balance performance in post stroke survivors

NCT ID: NCT03577002 Not yet recruiting - Cancer Clinical Trials

Team-based Versus Primary Care Clinician-led Advance Care Planning in Practice-based Research Networks

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This project compares two models of the Serious Illness Care Program (SICP) in primary care: clinician-focused SICP and team-based SICP. Discussion and planning for serious illness care can help patients identify what is most important to them and assure they receive care that best matches their goals and values, such as spending more time at home or not being in pain.