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Stroke clinical trials

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NCT ID: NCT04154969 Recruiting - Stroke Clinical Trials

The Effect of Vestibulo-ocular Reflex Improving Exercise on Gait and Balance Among Post Stroke Sub Acute Patients

Start date: November 10, 2019
Phase: N/A
Study type: Interventional

This study evaluate the effect of Vestibular rehabilitation program as part of physical therapy during rehabilitation post stroke. half of participants will receive vestibular exercise as part of the physiotherpy session, while the other half will receive a conservative physiotherapy session.

NCT ID: NCT04154514 Recruiting - Chronic Stroke Clinical Trials

A Potential Wearable for Post-stroke Rehabilitation

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Participants are seeking to unleash the full therapeutic potential of a newly developed, customizable and potentially commericializable 10-channel Functional Electrical Stimulation (FES) to rehabilitate the gait of chronic stroke survivors. Each subject will undergo 18-sessions (~1 month) FES training. Participants will utilize the theory of muscle synergies from motor neurosciences, which are defined as neural modules of motor control that coordinate the spatiotemporal activation patterns of multiple muscles, to guide our personal selections of muscles for FES. It is hypothesized that chronic stroke survivors will learn from FES stimulations, over several daily sessions, both by suppressing the original abnormal muscle synergies and by employing the normal muscle synergies as specified in the FES. It is also expected that the walk synergies of the paretic side of chronic stroke survivors should be more similar to healthy muscle synergies at the two post-training time points than before training.

NCT ID: NCT04152616 Recruiting - Stroke Sequelae Clinical Trials

Mechanisms of Balance Disorders in a Seated Position Following a Stroke

HEMISEAT
Start date: September 2020
Phase: N/A
Study type: Interventional

One of the causes of disability in stroke patients is postural disturbances that result in postural asymmetry in the standing position, characterized during an evaluation on a force platform by a greater displacement of the center of pressure towards the lesion side and thus by a greater percentage of weight on the lower limb (Weight -Bearing Asymmetry (WBA)). Today, the mechanisms of balance disorders in standing position are better understood. Indeed, in addition to sensory and motor deficits, spatial cognitive disorders also contribute to these postural disturbances, particularly in right brain damage stroke. This would be the reason why patients with right brain damage have a more precarious and time-consuming balance to re-educate than patients with lesions located in the left hemisphere. Postural disturbances can also result in a disturbance of balance in the sitting position, which is a poor prognosis for the acquisition of transfers, standing and walking. To date, seated postural disturbances are not perfectly described with many differences in the explanatory mechanisms found in the literature. Thus, some people notice a more pronounced asymmetry on the medio-lateral plane while others find a more pronounced imbalance at the antero-posterior plane. Sitting posture disorders benefit from few instrumental measurement tools outside clinical measurement scales. A very wide variety of evaluation methods by instrumental measurements are proposed and not validated. Sensor pad, which are usually used to adjust the bases of pressure ulcer patients, may be useful in quantifying the postural balance. But since the involvement of the head and trunk in the sitting posture is well documented in the literature, the addition of an evaluation of the position of the trunk and head seems essential. To our knowledge, no author has proposed to quantify sitting balance disorders by combining a measure of support asymmetry by taking into account the posture of the trunk with that of the head.

NCT ID: NCT04150835 Recruiting - Clinical trials for Acute Ischemic Stroke

Xingnaojing for Mild-to-severe Acute Ischemic Stroke

XMAS-2
Start date: March 19, 2020
Phase: Phase 4
Study type: Interventional

The main purpose of this trial is to determine whether Xingnaojing, intravenously administered within 24 hours of symptom onset, improves the daily living ability of acute ischemic stroke at 90 days.

NCT ID: NCT04143763 Recruiting - Stroke Clinical Trials

Mobile Message Intervention for Stroke Caregivers' Psychological Support

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

The proposed trial aims to test the feasibility of ecological momentary intervention on stroke caregivers' psychological distress.

NCT ID: NCT04142151 Recruiting - Ischemic Stroke Clinical Trials

Double Randomized and Placebo Controlled Trail of Sanchitongshu Combined Antiplatelet Drug to Prevent Ischemic Stroke

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

This clinical trail will evaluate the effect of Sanchitongshu combined with antiplatelet drugs (Aspirin or Clopidogrel) in the treatment of high-risk ischemic stroke patients in adults. Half of participants will receive SanchiTongshu and one of antiplatelet drugs (Aspirin or Clopidogrel) in combination, while the other half will receive a placebo and one of antiplatelet drugs (Aspirin or Clopidogrel).

NCT ID: NCT04141774 Recruiting - Stroke Clinical Trials

Stroke Rehabilitation Using Brain-Computer Interface (BCI) Technology

Start date: September 27, 2018
Phase: N/A
Study type: Interventional

The purpose of this research is to determine if functional muscle stimulation, directed by electroencephalogram (EEG) output, can increase the extent of stroke recovery on behavioral measures and induce brain plasticity as measured by functional magnetic resonance imaging (fMRI). Participants will include stroke patients with upper-limb hemiparesis and can expect to be on study for approximately 4 months.

NCT ID: NCT04135677 Recruiting - Stroke Clinical Trials

Clinical Outcomes Between Anticoagulation and DAPT Therapy in AF Patients Successfully Undergoing LAAO

Start date: November 11, 2022
Phase: Phase 4
Study type: Interventional

The objective of this study is to assess the efficacy and safety different dosage of rivaroxaban application versus dual antiplatelet therapy after successful closure of left atrial appendage using the LAMBRE device.

NCT ID: NCT04130503 Recruiting - Clinical trials for Obstructive Sleep Apnea

The Recovery in Stroke Using PAP Study

RISE-UP
Start date: September 1, 2019
Phase: N/A
Study type: Interventional

The proposed study is a randomized controlled trial among an anicipated 180 participants with acute ischemic stroke and mod/severe OSA diagnosed by ambulatory polysomnography (PSG) comparing PAP treatment with usual care concerning the primary outcome of functional recovery.

NCT ID: NCT04129203 Recruiting - Stroke, Acute Clinical Trials

Versi Retriever Approving Trial in Japan

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

This is Versi Retriever mechanical thrombectomy device approving study in Japan. Multi center, single arm, prospective registry trial. Physicians control trial, conducted my N Sakai, Kobe City Medical Center General Hospital.