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Pain clinical trials

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NCT ID: NCT04544631 Completed - Pain Clinical Trials

VR for Pediatric Burn Dressing Changes

Start date: December 1, 2016
Phase: N/A
Study type: Interventional

This study evaluated a smart phone virtual reality (VR) to manage pediatric burn dressing pain. A randomized controlled trial was conducted among 90 patients (6-17 years). Active VR participants played the game, passive VR group were immersed in the same VR without interactions, and a standard care group served as the control. One researcher administered VR and observed pain while another researcher administered post-trial survey that measured child's perceived pain and VR experience. Nurses were asked to report the clinical utility.

NCT ID: NCT04543435 Completed - Pain Clinical Trials

Investigation of Pain Coping Methods and Related Factors in Postmenopausal Women

Start date: September 17, 2020
Phase:
Study type: Observational

Musculoskeletal pain (MSP) reflects of musculoskeletal conditions related to tissues such as tendons, muscles, ligaments, nerves, and other joint structures. Coping strategies with pain are used to manage the pain and its impacts. The present study aimed to compare active and passive coping strategies used and pain severity in postmenopausal women according to their demographic characteristics. Also, the relationship between pain and coping strategies in postmenopausal women with cMSP will be examined.

NCT ID: NCT04543227 Completed - Pain Clinical Trials

Opioid Laws and Pediatric Use

Start date: September 10, 2020
Phase:
Study type: Observational

The legitimate need for opioid medications for acute pain management in pediatric trauma patients is recognized, however, the high dose and duration of opioid drugs prescribed by medical providers has been associated with an increased risk of opioid abuse and chronic use by patients. The overarching goal of application is to assess opioid use and outcomes of pediatric patients treated for either burn injuries or knee arthroscopy procedures at a large academic pediatric medical center before and after Ohio opioid prescription rules for acute pain were implemented on August 21, 2017. Also, to evaluate patient use of opioids at 90-days post-treatment.

NCT ID: NCT04542707 Recruiting - Pain Clinical Trials

Brainwave Activity Response on Common Physical Therapy Intervention

Start date: August 20, 2020
Phase: N/A
Study type: Interventional

This study is designed to evaluate the if there is a predictable patterns in brainwave activity and to see how this changes with external physical therapy interventions such as manipulation, soft tissue massage, and exercise.

NCT ID: NCT04539353 Recruiting - Chronic Pain Clinical Trials

HRV and Pain Intensity

Start date: December 14, 2020
Phase:
Study type: Observational

The aim of this study is to explore the association between pain intensity and heart rate variability in patients with chronic pain.

NCT ID: NCT04532775 Not yet recruiting - Pain Clinical Trials

Efficacy Of Magnesium In Radicular Pain When Added To Local Anesthetics And Steroids In Transforaminal Epidural Injection

Start date: August 30, 2020
Phase: Phase 1
Study type: Interventional

investigators want to assess the efficacy of magnesium in radicular lower limb pain when it is added to local anesthetics and steroids in the transforaminal epidural injections.

NCT ID: NCT04530162 Withdrawn - Pain Clinical Trials

Prevention of Post Herpetic Neuralgia by Ultrasound Guided Single Nerve Block in the ED

Start date: October 1, 2021
Phase:
Study type: Observational

Herpes zoster causes significant morbidity on over 1 million Americans every year. Although the majority of herpes zoster pain will self-resolve within one week, a significant proportion of patients will develop postherpetic neuralgia (PHN), which is characterized by debilitating pain that persists more than three months after the initial symptoms. Nerve blocks have been previously studied as a method to control herpes zoster pain in outpatient pain clinics and inpatient settings. This study aims to investigate whether emergency department ultrasound guided nerve blocks can prevent PHN and effectively treat acute herpes zoster pain.

NCT ID: NCT04530149 Terminated - Pain Clinical Trials

Vital Capacity in Ultrasound Guided Serratus Plane Block in ED Patients With Multiple Rib Fractures

Start date: November 1, 2021
Phase: Phase 4
Study type: Interventional

I. Background: Patients with multiple rib fractures are challenging from both pulmonary and analgesia perspectives. Adequate pain management is essential in prevention of complications secondary to decreased inspiratory volume. Significant morbidity and mortality of rib fractures is secondary to severe pain that limits ribcage movement, decreases inspiratory volumes and causes inadequate cough. Decreased vital capacity predisposes patients to atelectasis, abnormal mucous clearance and pneumonia. The objective of this study is to assess the efficacy of the serratus anterior plane block (SAPB) in improvement of vital capacity in patients with multiple unilateral rib fractures when compared to conventional management with medications. Currently, evidence of efficacy of SAPB in managing pain secondary to multiple rib fractures is limited to case reports and series, none of which evaluate vital capacity. II. Significance: The findings of this study may indicate that SAPB is superior to pharmacological management in increasing vital capacity in patients with multiple unilateral rib fractures and suggest SAPB for first line therapy in patients with rib fractures. The findings may decrease the risk of pulmonary complications as well as the use of opiates in management of multiple rib fractures in the Emergency Department especially in patients with numerous comorbidities and contraindications to conventional treatment modalities. This study may support the need for training emergency medicine physicians in bedside SAPB in order to provide the optimal therapy for patient with multiple unilateral rib fractures. III. Study Objectives: The primary objectives are to evaluate whether ultrasound guided SAPB results in a greater improvement in percent predicted vital capacity compared to standard therapy with a sham injection. The investigators will also evaluate pain scores and the safety profile of the SAPB procedure compared to those receiving standard analgesia. IV. Hypothesis: The primary hypothesis is that SAPB is superior to sham injection in improving the percent of predicted vital capacity. The secondary hypothesis is that SAPB will have greater improvement in pain scores and have a superior safety profile compared to placebo injection.

NCT ID: NCT04526132 Completed - Pain Clinical Trials

A Phase Ⅲ Clinical Study Trial of Felbinac Trometamol Injection in China

Start date: April 25, 2021
Phase: Phase 3
Study type: Interventional

A multi-center, randomized, double-blind, placebo parallel controlled phase Ⅲ clinical trial on the efficacy and safety of felbinac trometamol Injection in the treatment of moderate and severe postoperative pain.main purpose is to evaluate the efficacy of Felbinac Trometamol Injection in the treatment of moderate and severe pain after surgery.Secondary purpose is to evaluation the safety of Felbinac Trometamol Injection in the treatment of moderate and severe pain after surgery.

NCT ID: NCT04526093 Recruiting - Depression Clinical Trials

Real-World Evidence in Patient-Reported Outcomes for Medical Cannabis (MC-RWE)

MC-RWE
Start date: July 15, 2020
Phase:
Study type: Observational

This prospective observational study aims to describe the effectiveness of MC on pain, epilepsy, sleep and /or anxiety/depression in a cohorts of patients authorized to use MC, using pre-defined, validated self assessment scales.